Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden
OBJECTIVES: Previous studies on mortality and the incidence of cancer among workers at primary aluminum smelters have produced conclusive results indicating an elevated risk of bladder cancer. An increased risk of lung cancer has also been reported several times. The objective of this study was to e...
Published in: | Scandinavian Journal of Work, Environment & Health |
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Onkologi
2008
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ftumeauniv:oai:DiVA.org:umu-24844 2023-10-09T21:54:36+02:00 Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden Björ, Ove Damber, Lena Edström, Clarence Nilsson, Tohr 2008 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-24844 https://doi.org/10.5271/sjweh.1293 eng eng Onkologi Yrkes- och miljömedicin Scandinavian Journal of Work, Environment and Health, 0355-3140, 2008, 34:6, s. 463-470 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-24844 doi:10.5271/sjweh.1293 PMID 19137208 Scopus 2-s2.0-61549093442 info:eu-repo/semantics/openAccess Cancer and Oncology Cancer och onkologi Occupational Health and Environmental Health Arbetsmedicin och miljömedicin Article in journal info:eu-repo/semantics/article text 2008 ftumeauniv https://doi.org/10.5271/sjweh.1293 2023-09-22T13:57:39Z OBJECTIVES: Previous studies on mortality and the incidence of cancer among workers at primary aluminum smelters have produced conclusive results indicating an elevated risk of bladder cancer. An increased risk of lung cancer has also been reported several times. The objective of this study was to examine mortality and the incidence of cancer at a Swedish aluminum smelter when different neighboring reference populations were used to evaluate any relationships to the length of employment. METHODS: A historical cohort--comprised of 2264 male nonoffice workers employed from 1942 on and tracked up to the year 2000--was examined. With the use of three reference populations for mortality and four for cancer incidence, standardized mortality and incidence ratios were calculated, together with hazard ratios derived from Cox regression models. RESULTS: This study showed an excess risk of mortality due to chronic obstructive lung disease, mental disorders, and diseases of the digestive system among the short-term workers. An elevated risk of cancer was found for the lungs, central nervous system, and esophagus. The highest lung cancer risk was observed for the workers employed for > or = 10 years in the factory when they were compared with the reference group from northern Sweden (standardized incidence ratio 1.99, 95% confidence ratio 1.21-3.07). CONCLUSIONS: The results support previous studies that demonstrated an excess risk of lung cancer, but, in contrast to the results of most studies, cancer of the central nervous system was also elevated. This study did not, however, verify an association between this type of exposure and cancer of the urinary organs. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) Scandinavian Journal of Work, Environment & Health 34 6 463 470 |
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Open Polar |
collection |
Umeå University: Publications (DiVA) |
op_collection_id |
ftumeauniv |
language |
English |
topic |
Cancer and Oncology Cancer och onkologi Occupational Health and Environmental Health Arbetsmedicin och miljömedicin |
spellingShingle |
Cancer and Oncology Cancer och onkologi Occupational Health and Environmental Health Arbetsmedicin och miljömedicin Björ, Ove Damber, Lena Edström, Clarence Nilsson, Tohr Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
topic_facet |
Cancer and Oncology Cancer och onkologi Occupational Health and Environmental Health Arbetsmedicin och miljömedicin |
description |
OBJECTIVES: Previous studies on mortality and the incidence of cancer among workers at primary aluminum smelters have produced conclusive results indicating an elevated risk of bladder cancer. An increased risk of lung cancer has also been reported several times. The objective of this study was to examine mortality and the incidence of cancer at a Swedish aluminum smelter when different neighboring reference populations were used to evaluate any relationships to the length of employment. METHODS: A historical cohort--comprised of 2264 male nonoffice workers employed from 1942 on and tracked up to the year 2000--was examined. With the use of three reference populations for mortality and four for cancer incidence, standardized mortality and incidence ratios were calculated, together with hazard ratios derived from Cox regression models. RESULTS: This study showed an excess risk of mortality due to chronic obstructive lung disease, mental disorders, and diseases of the digestive system among the short-term workers. An elevated risk of cancer was found for the lungs, central nervous system, and esophagus. The highest lung cancer risk was observed for the workers employed for > or = 10 years in the factory when they were compared with the reference group from northern Sweden (standardized incidence ratio 1.99, 95% confidence ratio 1.21-3.07). CONCLUSIONS: The results support previous studies that demonstrated an excess risk of lung cancer, but, in contrast to the results of most studies, cancer of the central nervous system was also elevated. This study did not, however, verify an association between this type of exposure and cancer of the urinary organs. |
format |
Article in Journal/Newspaper |
author |
Björ, Ove Damber, Lena Edström, Clarence Nilsson, Tohr |
author_facet |
Björ, Ove Damber, Lena Edström, Clarence Nilsson, Tohr |
author_sort |
Björ, Ove |
title |
Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
title_short |
Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
title_full |
Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
title_fullStr |
Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
title_full_unstemmed |
Long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden |
title_sort |
long-term follow-up study of mortality and the incidence of cancer in a cohort of workers at a primary aluminum smelter in sweden |
publisher |
Onkologi |
publishDate |
2008 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-24844 https://doi.org/10.5271/sjweh.1293 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
Scandinavian Journal of Work, Environment and Health, 0355-3140, 2008, 34:6, s. 463-470 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-24844 doi:10.5271/sjweh.1293 PMID 19137208 Scopus 2-s2.0-61549093442 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.5271/sjweh.1293 |
container_title |
Scandinavian Journal of Work, Environment & Health |
container_volume |
34 |
container_issue |
6 |
container_start_page |
463 |
op_container_end_page |
470 |
_version_ |
1779318230334046208 |