Fragility fractures in fragile people : epidemiology of the age quake
Osteoporosis-related fracture is already today a major public health problem and the number of hip fractures is expected to double to 2030. Sweden has one of the highest hip fracture incidences worldwide. This may be explained by several factors: e.g. age, genetic, climatologic, geographic and a rel...
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ftumeauniv:oai:DiVA.org:umu-22729 2023-10-09T21:54:38+02:00 Fragility fractures in fragile people : epidemiology of the age quake Bergström, Ulrica 2009 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22729 eng eng Ortopedi Umeå : Institutionen för kirurgi och perioperativ vetenskap Umeå University medical dissertations, 0346-6612 1249 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22729 urn:isbn:978-91-7264-739-8 info:eu-repo/semantics/openAccess Fragility fractures elderly epidemiology age quake population based Vitamin D Surgery Kirurgi Doctoral thesis, comprehensive summary info:eu-repo/semantics/doctoralThesis text 2009 ftumeauniv 2023-09-22T13:46:55Z Osteoporosis-related fracture is already today a major public health problem and the number of hip fractures is expected to double to 2030. Sweden has one of the highest hip fracture incidences worldwide. This may be explained by several factors: e.g. age, genetic, climatologic, geographic and a relative vitamin D deficiency, secondary to the limited sunlight exposure especially during winter months. Intrinsic and extrinsic factors contribute to a fracture, although a prior low energy fracture is one of the strongest predictors for a subsequent one and this should be a target for secondary fracture prevention in an orthopaedic setting. Since 1993 all injured patients admitted to the emergency floor and all in-hospital fractures at Umeå University Hospital, Sweden, were registered according to the Injury Data Base, former EHLASS. There were 31,173 fracture events (one or more fractures at the same time), of which 13,931 were in patients’ ≥ 50 years old. The fracture database was co analyzed with the Northern Sweden Health and Disease Study cohort in a nested case-control study for investigations of associations between osteoporotic fracture and serum markers, lifestyle data, nutrition etc. We found that there were differences in fracture pattern depending on age and sex. Both injury mechanism and fracture site were strongly dependent of age. The most severe fragility fracture, hip fracture, had a decreasing incidence. However, the incidence curve was right-shifting leading to an increase, both in numbers and in incidence of hip fractures among the oldest female. To identify people at high risk for fractures, re-fracture patients are useful. No less than 21% of the fracture patients had suffered more than one fracture event, accounting for 38% of all fracture events. The total risk ratio for a subsequent fracture was 2.2 (2.1-2.3 95% CI). In males the highest risk for re fracture was in the age cohort 70-79 years (RR 2.7, 2.3-3.2 95% CI), in females > 90 years (RR 3.9, 3.2-4.8 95% CI). Another possible risk ... Doctoral or Postdoctoral Thesis Northern Sweden Umeå University: Publications (DiVA) |
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Umeå University: Publications (DiVA) |
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language |
English |
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Fragility fractures elderly epidemiology age quake population based Vitamin D Surgery Kirurgi |
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Fragility fractures elderly epidemiology age quake population based Vitamin D Surgery Kirurgi Bergström, Ulrica Fragility fractures in fragile people : epidemiology of the age quake |
topic_facet |
Fragility fractures elderly epidemiology age quake population based Vitamin D Surgery Kirurgi |
description |
Osteoporosis-related fracture is already today a major public health problem and the number of hip fractures is expected to double to 2030. Sweden has one of the highest hip fracture incidences worldwide. This may be explained by several factors: e.g. age, genetic, climatologic, geographic and a relative vitamin D deficiency, secondary to the limited sunlight exposure especially during winter months. Intrinsic and extrinsic factors contribute to a fracture, although a prior low energy fracture is one of the strongest predictors for a subsequent one and this should be a target for secondary fracture prevention in an orthopaedic setting. Since 1993 all injured patients admitted to the emergency floor and all in-hospital fractures at Umeå University Hospital, Sweden, were registered according to the Injury Data Base, former EHLASS. There were 31,173 fracture events (one or more fractures at the same time), of which 13,931 were in patients’ ≥ 50 years old. The fracture database was co analyzed with the Northern Sweden Health and Disease Study cohort in a nested case-control study for investigations of associations between osteoporotic fracture and serum markers, lifestyle data, nutrition etc. We found that there were differences in fracture pattern depending on age and sex. Both injury mechanism and fracture site were strongly dependent of age. The most severe fragility fracture, hip fracture, had a decreasing incidence. However, the incidence curve was right-shifting leading to an increase, both in numbers and in incidence of hip fractures among the oldest female. To identify people at high risk for fractures, re-fracture patients are useful. No less than 21% of the fracture patients had suffered more than one fracture event, accounting for 38% of all fracture events. The total risk ratio for a subsequent fracture was 2.2 (2.1-2.3 95% CI). In males the highest risk for re fracture was in the age cohort 70-79 years (RR 2.7, 2.3-3.2 95% CI), in females > 90 years (RR 3.9, 3.2-4.8 95% CI). Another possible risk ... |
format |
Doctoral or Postdoctoral Thesis |
author |
Bergström, Ulrica |
author_facet |
Bergström, Ulrica |
author_sort |
Bergström, Ulrica |
title |
Fragility fractures in fragile people : epidemiology of the age quake |
title_short |
Fragility fractures in fragile people : epidemiology of the age quake |
title_full |
Fragility fractures in fragile people : epidemiology of the age quake |
title_fullStr |
Fragility fractures in fragile people : epidemiology of the age quake |
title_full_unstemmed |
Fragility fractures in fragile people : epidemiology of the age quake |
title_sort |
fragility fractures in fragile people : epidemiology of the age quake |
publisher |
Ortopedi |
publishDate |
2009 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22729 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
Umeå University medical dissertations, 0346-6612 1249 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22729 urn:isbn:978-91-7264-739-8 |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1779318309881118720 |