Risk markers and incidence of atrial fibrillation in northern Sweden
Background: Atrial fibrillation (AF) is the most common clinically significant arrythmia with a prevalence of approximately 3% in the general population. Less is known about the incidence of AF. In order to reduce the incidence of AF, it is of essence to identify modifiable risk factors for the dise...
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Umeå universitet, Institutionen för folkhälsa och klinisk medicin
2023
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ftumeauniv:oai:DiVA.org:umu-207051 2024-04-28T08:29:14+00:00 Risk markers and incidence of atrial fibrillation in northern Sweden Riskmarkörer och incidens av förmaksflimmer i norra Sverige Johansson, Cecilia 2023 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-207051 eng eng UmeÃ¥ universitet, Institutionen för folkhälsa och klinisk medicin UmeÃ¥ : UmeÃ¥ University UmeÃ¥ University medical dissertations, 0346-6612 2223 orcid:0000-0001-9972-5893 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-207051 urn:isbn:978-91-7855-977-0 urn:isbn:978-91-7855-978-7 info:eu-repo/semantics/openAccess Atrial fibrillation atrial flutter incidence provoking factors types of atiral fibrillation stroke risk alcohol consumption problem drinking weight height weight change normal blood pressure high normal blood pressure Förmaksflimmer förmaksfladder incidens provocerande faktorer typer av förmaksflimmer strokerisk alkoholkonsumtion alkoholproblem vikt längd viktförändring normalt blodtryck högt normalt blodtryck Other Clinical Medicine Annan klinisk medicin Doctoral thesis, comprehensive summary info:eu-repo/semantics/doctoralThesis text 2023 ftumeauniv 2024-04-09T23:38:33Z Background: Atrial fibrillation (AF) is the most common clinically significant arrythmia with a prevalence of approximately 3% in the general population. Less is known about the incidence of AF. In order to reduce the incidence of AF, it is of essence to identify modifiable risk factors for the disease. Aims: The aims of this thesis were (1) to estimate the incidence of AF and to assess the prevalence of provoking factors and risk factors for stroke and systemic embolism at the time of AF diagnosis, (2) to study the association between alcohol consumption and risk of AF, (3) to study the association between weight, height, weight change, and risk of AF, and (4) to study the association between normal or high normal blood pressure (BP), compared to optimal BP, and risk of AF. Methods: To determine the incidence of AF and the prevalence of provoking factors and risk factors for stroke and systemic embolism at AF diagnosis, an observational study was performed between January 1, 2011, and December 31, 2012, in the municipalities of SkellefteÃ¥ and Norsjö, Västerbotten, Sweden. Diagnosis registries were searched for cases of incident AF. All AF diagnoses were verified by electrocardiogram. Data regarding provoking factors, type of AF and presence of risk factors for stroke and systemic embolism (as assessed by the CHA2DS2-VASc score) was obtained from medical records. Incidence was calculated by dividing the number of incident AF cases by the time at risk for the population. The association between alcohol consumption, weight, height, weight change, normal BP, high normal BP, and risk of AF was investigated in a population-based cohort study of participants of the Västerbotten Intervention Programme (VIP). Residents of Västerbotten County aged 30, 40, 50 and 60 years who had participated in the VIP health examinations between January 1, 1988, and September 5, 2014, were included. Individuals who had been diagnosed with AF before participating in the VIP were excluded. Study participants were followed until a ... Doctoral or Postdoctoral Thesis Norra Sverige Northern Sweden Umeå University: Publications (DiVA) |
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Umeå University: Publications (DiVA) |
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ftumeauniv |
language |
English |
topic |
Atrial fibrillation atrial flutter incidence provoking factors types of atiral fibrillation stroke risk alcohol consumption problem drinking weight height weight change normal blood pressure high normal blood pressure Förmaksflimmer förmaksfladder incidens provocerande faktorer typer av förmaksflimmer strokerisk alkoholkonsumtion alkoholproblem vikt längd viktförändring normalt blodtryck högt normalt blodtryck Other Clinical Medicine Annan klinisk medicin |
spellingShingle |
Atrial fibrillation atrial flutter incidence provoking factors types of atiral fibrillation stroke risk alcohol consumption problem drinking weight height weight change normal blood pressure high normal blood pressure Förmaksflimmer förmaksfladder incidens provocerande faktorer typer av förmaksflimmer strokerisk alkoholkonsumtion alkoholproblem vikt längd viktförändring normalt blodtryck högt normalt blodtryck Other Clinical Medicine Annan klinisk medicin Johansson, Cecilia Risk markers and incidence of atrial fibrillation in northern Sweden |
topic_facet |
Atrial fibrillation atrial flutter incidence provoking factors types of atiral fibrillation stroke risk alcohol consumption problem drinking weight height weight change normal blood pressure high normal blood pressure Förmaksflimmer förmaksfladder incidens provocerande faktorer typer av förmaksflimmer strokerisk alkoholkonsumtion alkoholproblem vikt längd viktförändring normalt blodtryck högt normalt blodtryck Other Clinical Medicine Annan klinisk medicin |
description |
Background: Atrial fibrillation (AF) is the most common clinically significant arrythmia with a prevalence of approximately 3% in the general population. Less is known about the incidence of AF. In order to reduce the incidence of AF, it is of essence to identify modifiable risk factors for the disease. Aims: The aims of this thesis were (1) to estimate the incidence of AF and to assess the prevalence of provoking factors and risk factors for stroke and systemic embolism at the time of AF diagnosis, (2) to study the association between alcohol consumption and risk of AF, (3) to study the association between weight, height, weight change, and risk of AF, and (4) to study the association between normal or high normal blood pressure (BP), compared to optimal BP, and risk of AF. Methods: To determine the incidence of AF and the prevalence of provoking factors and risk factors for stroke and systemic embolism at AF diagnosis, an observational study was performed between January 1, 2011, and December 31, 2012, in the municipalities of Skellefteå and Norsjö, Västerbotten, Sweden. Diagnosis registries were searched for cases of incident AF. All AF diagnoses were verified by electrocardiogram. Data regarding provoking factors, type of AF and presence of risk factors for stroke and systemic embolism (as assessed by the CHA2DS2-VASc score) was obtained from medical records. Incidence was calculated by dividing the number of incident AF cases by the time at risk for the population. The association between alcohol consumption, weight, height, weight change, normal BP, high normal BP, and risk of AF was investigated in a population-based cohort study of participants of the Västerbotten Intervention Programme (VIP). Residents of Västerbotten County aged 30, 40, 50 and 60 years who had participated in the VIP health examinations between January 1, 1988, and September 5, 2014, were included. Individuals who had been diagnosed with AF before participating in the VIP were excluded. Study participants were followed until a ... |
format |
Doctoral or Postdoctoral Thesis |
author |
Johansson, Cecilia |
author_facet |
Johansson, Cecilia |
author_sort |
Johansson, Cecilia |
title |
Risk markers and incidence of atrial fibrillation in northern Sweden |
title_short |
Risk markers and incidence of atrial fibrillation in northern Sweden |
title_full |
Risk markers and incidence of atrial fibrillation in northern Sweden |
title_fullStr |
Risk markers and incidence of atrial fibrillation in northern Sweden |
title_full_unstemmed |
Risk markers and incidence of atrial fibrillation in northern Sweden |
title_sort |
risk markers and incidence of atrial fibrillation in northern sweden |
publisher |
Umeå universitet, Institutionen för folkhälsa och klinisk medicin |
publishDate |
2023 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-207051 |
genre |
Norra Sverige Northern Sweden |
genre_facet |
Norra Sverige Northern Sweden |
op_relation |
Umeå University medical dissertations, 0346-6612 2223 orcid:0000-0001-9972-5893 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-207051 urn:isbn:978-91-7855-977-0 urn:isbn:978-91-7855-978-7 |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1797587539460096000 |