Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care
Aim: Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis. Methods: Information on preterm infants in the 21 greater healthcare regions of Denmark...
Published in: | Acta Paediatrica |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Umeå universitet, Pediatrik
2023
|
Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206347 https://doi.org/10.1111/apa.16753 |
id |
ftumeauniv:oai:DiVA.org:umu-206347 |
---|---|
record_format |
openpolar |
institution |
Open Polar |
collection |
Umeå University: Publications (DiVA) |
op_collection_id |
ftumeauniv |
language |
English |
topic |
gestational age mortality neonatal care Nordic country premature Pediatrics Pediatrik |
spellingShingle |
gestational age mortality neonatal care Nordic country premature Pediatrics Pediatrik Norman, Mikael Padkær Petersen, Jesper Stensvold, Hans Jørgen Thorkelsson, Thordur Helenius, Kjell Brix Andersson, Charlotte Ørum Cueto, Heidi Domellöf, Magnus Gissler, Mika Heino, Anna Håkansson, Stellan Jonsson, Baldvin Klingenberg, Claus Lehtonen, Liisa Metsäranta, Marjo Rønnestad, Arild E. Trautner, Simon Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
topic_facet |
gestational age mortality neonatal care Nordic country premature Pediatrics Pediatrik |
description |
Aim: Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis. Methods: Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm birth rates, case-mix, perinatal interventions, neonatal morbidity and survival to hospital discharge in very (<32 weeks) and extremely preterm infants (<28 weeks of gestational age) were compared. Results: Out of 287 642 infants born alive, 16 567 (5.8%) were preterm, 2389 (0.83%) very preterm and 800 (0.28%) were extremely preterm. In very preterm infants, exposure to antenatal corticosteroids varied from 85% to 98%, live births occurring at regional centres from 48% to 100%, surfactant treatment from 28% to 69% and use of mechanical ventilation varied from 13% to 77% (p < 0.05 for all comparisons). Significant regional variations within and between countries were also seen in capacity in neonatal care, case-mix and number of admissions, whereas there were no statistically significant differences in survival or major neonatal morbidities. Conclusion: Management of very preterm infants exhibited significant regional variations in the Nordic countries. |
format |
Article in Journal/Newspaper |
author |
Norman, Mikael Padkær Petersen, Jesper Stensvold, Hans Jørgen Thorkelsson, Thordur Helenius, Kjell Brix Andersson, Charlotte Ørum Cueto, Heidi Domellöf, Magnus Gissler, Mika Heino, Anna Håkansson, Stellan Jonsson, Baldvin Klingenberg, Claus Lehtonen, Liisa Metsäranta, Marjo Rønnestad, Arild E. Trautner, Simon |
author_facet |
Norman, Mikael Padkær Petersen, Jesper Stensvold, Hans Jørgen Thorkelsson, Thordur Helenius, Kjell Brix Andersson, Charlotte Ørum Cueto, Heidi Domellöf, Magnus Gissler, Mika Heino, Anna Håkansson, Stellan Jonsson, Baldvin Klingenberg, Claus Lehtonen, Liisa Metsäranta, Marjo Rønnestad, Arild E. Trautner, Simon |
author_sort |
Norman, Mikael |
title |
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
title_short |
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
title_full |
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
title_fullStr |
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
title_full_unstemmed |
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care |
title_sort |
preterm birth in the nordic countries—capacity, management and outcome in neonatal care |
publisher |
Umeå universitet, Pediatrik |
publishDate |
2023 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206347 https://doi.org/10.1111/apa.16753 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Acta Paediatrica, 0803-5253, 2023, 112:7, s. 1422-1433 orcid:0000-0002-0726-7029 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206347 doi:10.1111/apa.16753 PMID 36912750 ISI:000957038000001 Scopus 2-s2.0-85150900950 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1111/apa.16753 |
container_title |
Acta Paediatrica |
_version_ |
1779315960379867136 |
spelling |
ftumeauniv:oai:DiVA.org:umu-206347 2023-10-09T21:52:46+02:00 Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care Norman, Mikael Padkær Petersen, Jesper Stensvold, Hans Jørgen Thorkelsson, Thordur Helenius, Kjell Brix Andersson, Charlotte Ørum Cueto, Heidi Domellöf, Magnus Gissler, Mika Heino, Anna Håkansson, Stellan Jonsson, Baldvin Klingenberg, Claus Lehtonen, Liisa Metsäranta, Marjo Rønnestad, Arild E. Trautner, Simon 2023 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206347 https://doi.org/10.1111/apa.16753 eng eng Umeå universitet, Pediatrik Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Neonatal Medicine, Karolinska University Hospital, Stockholm, Sweden The Danish Clinical Quality Program – National Clinical Registries (RKKP), Aarhus, Denmark; Department of Paediatrics, Aarhus University Hospital, Aarhus, Denmark Department of Neonatal Intensive Care, Clinic of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway Department of Neonatal Medicine, Children's Hospital Iceland, Landspitali University Hospital, Reykjavík, Iceland Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland; Department of Clinical Medicine, University of Turku, Turku, Finland The Danish Clinical Quality Program – National Clinical Registries (RKKP), Aarhus, Denmark; Department of Obstetrics and Gynaecology, Aalborg University Hospital, Thisted, Denmark The Danish Clinical Quality Program – National Clinical Registries (RKKP), Aarhus, Denmark Department of Knowledge Brokers, THL Finnish Institute for Health and Welfare, Helsinki, Finland Department of Neonatal Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden Paediatric Research Group, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway; Department of Paediatrics and Adolescence Medicine, University Hospital of North Norway, Tromsø, Norway Department of Paediatrics, New Children's Hospital, Paediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Department of Neonatal Intensive Care, Clinic of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway; Medical Faculty, Institute for Clinical Medicine, University of Oslo, Oslo, Norway The Danish Clinical Quality Program – National Clinical Registries (RKKP), Aarhus, Acta Paediatrica, 0803-5253, 2023, 112:7, s. 1422-1433 orcid:0000-0002-0726-7029 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206347 doi:10.1111/apa.16753 PMID 36912750 ISI:000957038000001 Scopus 2-s2.0-85150900950 info:eu-repo/semantics/openAccess gestational age mortality neonatal care Nordic country premature Pediatrics Pediatrik Article in journal info:eu-repo/semantics/article text 2023 ftumeauniv https://doi.org/10.1111/apa.16753 2023-09-22T14:00:39Z Aim: Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis. Methods: Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm birth rates, case-mix, perinatal interventions, neonatal morbidity and survival to hospital discharge in very (<32 weeks) and extremely preterm infants (<28 weeks of gestational age) were compared. Results: Out of 287 642 infants born alive, 16 567 (5.8%) were preterm, 2389 (0.83%) very preterm and 800 (0.28%) were extremely preterm. In very preterm infants, exposure to antenatal corticosteroids varied from 85% to 98%, live births occurring at regional centres from 48% to 100%, surfactant treatment from 28% to 69% and use of mechanical ventilation varied from 13% to 77% (p < 0.05 for all comparisons). Significant regional variations within and between countries were also seen in capacity in neonatal care, case-mix and number of admissions, whereas there were no statistically significant differences in survival or major neonatal morbidities. Conclusion: Management of very preterm infants exhibited significant regional variations in the Nordic countries. Article in Journal/Newspaper Iceland Umeå University: Publications (DiVA) Norway Acta Paediatrica |