Incidence and risk factors of venous thromboembolism in men and women
Introduction: Studies have indicated that men have a higher overall risk of VTE than women. In previous studies, we have noted that risk factors for VTE, such as alcohol consumption and physical activity, can differ between sexes. The aim of the present study was to estimate the incidence of first-e...
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Umeå universitet, Avdelningen för medicin
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ftumeauniv:oai:DiVA.org:umu-195061 2023-10-09T21:54:36+02:00 Incidence and risk factors of venous thromboembolism in men and women Lind, Marcus Johansson, Magdalena Själander, Anders Johansson, Lars 2022 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-195061 https://doi.org/10.1016/j.thromres.2022.04.014 eng eng Umeå universitet, Avdelningen för medicin Thrombosis Research, 0049-3848, 2022, 214, s. 82-86 orcid:0000-0003-4423-4135 orcid:0000-0001-9422-1186 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-195061 doi:10.1016/j.thromres.2022.04.014 PMID 35523076 ISI:000800176100006 Scopus 2-s2.0-85129943754 info:eu-repo/semantics/openAccess Arterial Hypertension Risk factors Venous thromboembolism Cardiac and Cardiovascular Systems Kardiologi Article in journal info:eu-repo/semantics/article text 2022 ftumeauniv https://doi.org/10.1016/j.thromres.2022.04.014 2023-09-22T14:01:26Z Introduction: Studies have indicated that men have a higher overall risk of VTE than women. In previous studies, we have noted that risk factors for VTE, such as alcohol consumption and physical activity, can differ between sexes. The aim of the present study was to estimate the incidence of first-ever VTE and the association of traditional cardiovascular risk factors with VTE risk in men and women separately. Materials and methods: Inhabitants of Västerbotten County in northern Sweden, who had participated in a health examination between 1985 and 2014 were included. The mean age at inclusion was 46.3 years (range 26–65 years). All first-ever VTE events experienced by the participants from the health examination to September 5, 2014 were identified and validated. Results: A total of 1110 men and 944 women had an objectively verified first-ever VTE event. The incidence of VTE was 1.54 (95% CI 1.45–1.63) per 1000 years of follow-up for men and 1.22 (95% CI 1.14–1.30) for women. Higher age, weight and body mass index were associated with increased risk of VTE in both sexes. Men with hypertension had a lower risk of VTE, HR 0.75 (95% CI 0.65–0.87) and men with more than secondary school education had a higher risk of VTE. Taller women had an increased risk of VTE. Conclusions: In the studied age group, we found that men had a higher incidence of first-ever VTE than women. Notably, we also found that hypertension was associated with lower risk of VTE in men but not in women. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) Thrombosis Research 214 82 86 |
institution |
Open Polar |
collection |
Umeå University: Publications (DiVA) |
op_collection_id |
ftumeauniv |
language |
English |
topic |
Arterial Hypertension Risk factors Venous thromboembolism Cardiac and Cardiovascular Systems Kardiologi |
spellingShingle |
Arterial Hypertension Risk factors Venous thromboembolism Cardiac and Cardiovascular Systems Kardiologi Lind, Marcus Johansson, Magdalena Själander, Anders Johansson, Lars Incidence and risk factors of venous thromboembolism in men and women |
topic_facet |
Arterial Hypertension Risk factors Venous thromboembolism Cardiac and Cardiovascular Systems Kardiologi |
description |
Introduction: Studies have indicated that men have a higher overall risk of VTE than women. In previous studies, we have noted that risk factors for VTE, such as alcohol consumption and physical activity, can differ between sexes. The aim of the present study was to estimate the incidence of first-ever VTE and the association of traditional cardiovascular risk factors with VTE risk in men and women separately. Materials and methods: Inhabitants of Västerbotten County in northern Sweden, who had participated in a health examination between 1985 and 2014 were included. The mean age at inclusion was 46.3 years (range 26–65 years). All first-ever VTE events experienced by the participants from the health examination to September 5, 2014 were identified and validated. Results: A total of 1110 men and 944 women had an objectively verified first-ever VTE event. The incidence of VTE was 1.54 (95% CI 1.45–1.63) per 1000 years of follow-up for men and 1.22 (95% CI 1.14–1.30) for women. Higher age, weight and body mass index were associated with increased risk of VTE in both sexes. Men with hypertension had a lower risk of VTE, HR 0.75 (95% CI 0.65–0.87) and men with more than secondary school education had a higher risk of VTE. Taller women had an increased risk of VTE. Conclusions: In the studied age group, we found that men had a higher incidence of first-ever VTE than women. Notably, we also found that hypertension was associated with lower risk of VTE in men but not in women. |
format |
Article in Journal/Newspaper |
author |
Lind, Marcus Johansson, Magdalena Själander, Anders Johansson, Lars |
author_facet |
Lind, Marcus Johansson, Magdalena Själander, Anders Johansson, Lars |
author_sort |
Lind, Marcus |
title |
Incidence and risk factors of venous thromboembolism in men and women |
title_short |
Incidence and risk factors of venous thromboembolism in men and women |
title_full |
Incidence and risk factors of venous thromboembolism in men and women |
title_fullStr |
Incidence and risk factors of venous thromboembolism in men and women |
title_full_unstemmed |
Incidence and risk factors of venous thromboembolism in men and women |
title_sort |
incidence and risk factors of venous thromboembolism in men and women |
publisher |
Umeå universitet, Avdelningen för medicin |
publishDate |
2022 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-195061 https://doi.org/10.1016/j.thromres.2022.04.014 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
Thrombosis Research, 0049-3848, 2022, 214, s. 82-86 orcid:0000-0003-4423-4135 orcid:0000-0001-9422-1186 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-195061 doi:10.1016/j.thromres.2022.04.014 PMID 35523076 ISI:000800176100006 Scopus 2-s2.0-85129943754 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1016/j.thromres.2022.04.014 |
container_title |
Thrombosis Research |
container_volume |
214 |
container_start_page |
82 |
op_container_end_page |
86 |
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1779318237357408256 |