Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

BACKGROUND: Systemic inflammatory response in colorectal cancer (CRC) has been established as a prognostic factor for impaired cancer-specific survival, predominantly in patients with right-sided tumors. On the other hand, defective mismatch repair (dMMR) tumors, primarily located in the right colon...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Gunnarsson, Ulf, Strigård, Karin, Edin, Sofia, Gkekas, Ioannis, Mustonen, Harri, Kaprio, Tuomas, Böckelman, Camilla, Hagström, Jaana, Palmqvist, Richard, Haglund, Caj
Format: Article in Journal/Newspaper
Language:English
Published: Umeå universitet, Kirurgi 2020
Subjects:
Colorectal cancer
Local immune response
Miscrosatellite instability
Mismatch repair
Systematic inflammatory response
Cancer and Oncology
Cancer och onkologi
Sigrid
Northern Sweden
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-170488
https://doi.org/10.1186/s12967-020-02336-6

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