Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort
Objective: To study asthma exacerbations, healthcare utilization and health status among subjects with asthma with different treatment regimens and levels of asthma control. Methods: In 2012-2014, n = 1425 adults from a population-based asthma cohort within the OLIN studies (Obstructive Lung disease...
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Umeå universitet, Avdelningen för medicin
2021
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ftumeauniv:oai:DiVA.org:umu-167772 2023-10-09T21:54:35+02:00 Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort Stridsman, Caroline Axelsson, Malin Warm, Katja Backman, Helena 2021 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167772 https://doi.org/10.1080/02770903.2020.1713150 eng eng Umeå universitet, Avdelningen för medicin Umeå universitet, Avdelningen för hållbar hälsa Division of Nursing, Department of Health Sciences, Luleå University of Technology, Luleå, Sweden. Department of Care Sciences, Faculty of Health and Society, Malmö University, Malmö, Sweden. Journal of Asthma, 0277-0903, 2021, 58:5, s. 586-595 orcid:0000-0002-0553-8067 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167772 doi:10.1080/02770903.2020.1713150 PMID 31910044 ISI:000506948200001 Scopus 2-s2.0-85088063526 info:eu-repo/semantics/openAccess Epidemiology management/control quality of life treatment Respiratory Medicine and Allergy Lungmedicin och allergi Article in journal info:eu-repo/semantics/article text 2021 ftumeauniv https://doi.org/10.1080/02770903.2020.1713150 2023-09-22T13:54:19Z Objective: To study asthma exacerbations, healthcare utilization and health status among subjects with asthma with different treatment regimens and levels of asthma control. Methods: In 2012-2014, n = 1425 adults from a population-based asthma cohort within the OLIN studies (Obstructive Lung disease in Northern Sweden) were invited to a follow-up including spirometry and a structured interview, n = 1006 participated. Asthma Control Test (ACT) was used to detect uncontrolled asthma, and physical and mental dimensions of health were measured with SF-8. Pharmacological treatment use was classified by Global Initiative for Asthma treatment steps. Out of n = 830 with current asthma, n = 714 answered ACT (57% women, 32-92 years) and were included in the study. Results: Uncontrolled asthma increased per treatment step (no treatment 9.9%, treatment step 1-3 24.1%, and treatment steps 4-5 39.9%, p < 0.001). A higher proportion of subjects with uncontrolled asthma reported exacerbations, healthcare utilization, and worse health status than those with controlled asthma. The proportion of subjects reporting exacerbations, healthcare visits, emergency room visits and regular follow-up visits increased per treatment step. Worse health was associated with uncontrolled asthma, but not with the level of treatment. A higher proportion of women than men reported exacerbations, any healthcare visits, and lower health. Regular follow-up visits to a physician were uncommon (women 21.2% vs. men 14.6%, p = 0.022). Conclusions: Uncontrolled asthma is common in all treatment steps, and is associated with worse health status. However, health status did not differ by treatment steps. Identifying subjects with uncontrolled asthma regardless of treatment regimens should be a priority, thus follow-up visits are important. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) Journal of Asthma 58 5 586 595 |
institution |
Open Polar |
collection |
Umeå University: Publications (DiVA) |
op_collection_id |
ftumeauniv |
language |
English |
topic |
Epidemiology management/control quality of life treatment Respiratory Medicine and Allergy Lungmedicin och allergi |
spellingShingle |
Epidemiology management/control quality of life treatment Respiratory Medicine and Allergy Lungmedicin och allergi Stridsman, Caroline Axelsson, Malin Warm, Katja Backman, Helena Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
topic_facet |
Epidemiology management/control quality of life treatment Respiratory Medicine and Allergy Lungmedicin och allergi |
description |
Objective: To study asthma exacerbations, healthcare utilization and health status among subjects with asthma with different treatment regimens and levels of asthma control. Methods: In 2012-2014, n = 1425 adults from a population-based asthma cohort within the OLIN studies (Obstructive Lung disease in Northern Sweden) were invited to a follow-up including spirometry and a structured interview, n = 1006 participated. Asthma Control Test (ACT) was used to detect uncontrolled asthma, and physical and mental dimensions of health were measured with SF-8. Pharmacological treatment use was classified by Global Initiative for Asthma treatment steps. Out of n = 830 with current asthma, n = 714 answered ACT (57% women, 32-92 years) and were included in the study. Results: Uncontrolled asthma increased per treatment step (no treatment 9.9%, treatment step 1-3 24.1%, and treatment steps 4-5 39.9%, p < 0.001). A higher proportion of subjects with uncontrolled asthma reported exacerbations, healthcare utilization, and worse health status than those with controlled asthma. The proportion of subjects reporting exacerbations, healthcare visits, emergency room visits and regular follow-up visits increased per treatment step. Worse health was associated with uncontrolled asthma, but not with the level of treatment. A higher proportion of women than men reported exacerbations, any healthcare visits, and lower health. Regular follow-up visits to a physician were uncommon (women 21.2% vs. men 14.6%, p = 0.022). Conclusions: Uncontrolled asthma is common in all treatment steps, and is associated with worse health status. However, health status did not differ by treatment steps. Identifying subjects with uncontrolled asthma regardless of treatment regimens should be a priority, thus follow-up visits are important. |
format |
Article in Journal/Newspaper |
author |
Stridsman, Caroline Axelsson, Malin Warm, Katja Backman, Helena |
author_facet |
Stridsman, Caroline Axelsson, Malin Warm, Katja Backman, Helena |
author_sort |
Stridsman, Caroline |
title |
Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
title_short |
Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
title_full |
Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
title_fullStr |
Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
title_full_unstemmed |
Uncontrolled asthma occurs in all GINA treatment steps and is associated with worse physical health : a report from the OLIN adult asthma cohort |
title_sort |
uncontrolled asthma occurs in all gina treatment steps and is associated with worse physical health : a report from the olin adult asthma cohort |
publisher |
Umeå universitet, Avdelningen för medicin |
publishDate |
2021 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167772 https://doi.org/10.1080/02770903.2020.1713150 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
Journal of Asthma, 0277-0903, 2021, 58:5, s. 586-595 orcid:0000-0002-0553-8067 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167772 doi:10.1080/02770903.2020.1713150 PMID 31910044 ISI:000506948200001 Scopus 2-s2.0-85088063526 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1080/02770903.2020.1713150 |
container_title |
Journal of Asthma |
container_volume |
58 |
container_issue |
5 |
container_start_page |
586 |
op_container_end_page |
595 |
_version_ |
1779318203378302976 |