Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study
Purpose: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We e...
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Umeå universitet, Avdelningen för medicin
2020
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ftumeauniv:oai:DiVA.org:umu-166576 2024-09-15T18:26:02+00:00 Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor 2020 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166576 https://doi.org/10.1007/s00394-019-02142-x eng eng UmeÃ¥ universitet, Avdelningen för medicin UmeÃ¥ universitet, Kardiologi Research and Innovation Unit, Norrbotten County Council, LuleÃ¥, Sweden European Journal of Nutrition, 1436-6207, 2020, 59:7, s. 3037-3044 orcid:0000-0003-4059-3368 orcid:0000-0001-9225-1306 orcid:0000-0002-2936-2895 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166576 doi:10.1007/s00394-019-02142-x PMID 31754783 ISI:000497816400001 Scopus 2-s2.0-85075367003 info:eu-repo/semantics/openAccess Vitamin D Trend Cross-sectional study MONICA Sweden Nutrition and Dietetics Näringslära Article in journal info:eu-repo/semantics/article text 2020 ftumeauniv https://doi.org/10.1007/s00394-019-02142-x 2024-08-20T23:39:49Z Purpose: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We examined the time trend of vitamin D concentrations in northern Sweden between 1986 and 2014. Methods: We used data on 11,129 men and women (aged 25–74 years) from seven population-based surveys (the Northern Sweden MONICA study), recruited between 1986 and 2014. Serum vitamin D (25-hydroxyvitamin D) status was measured using a one-step immunoassay (Abbott Architect). Multivariable linear regression models, adjusted for age, sex, and a number of other variables, were used to estimate the time trend of vitamin D concentrations. Results: The mean value of vitamin D in the entire study population was 19.9 ng/mL [standard deviation (SD) 7.9], with lower values in men (19.4 ng/mL; SD 7.5) than in women (20.5 ng/mL; SD 8.2). Using the survey in 1986 as reference category, the multivariable-adjusted mean difference [95% confidence interval (CI)] in ng/mL was 2.7 (2.2, 3.3) in 1990, 3.2 (2.7, 3.7) in 1994, 1.6 (1.0, 2.1) in 1999, − 2.0 (− 2.5, − 1.4) in 2004, 1.0 (0.4, 1.5) in 2009, and 3.1 (2.5, 3.6) in 2014. Conclusion: In this large cross-sectional study, we observed no clear upward or downward trend of vitamin D concentrations in northern Sweden between 1986 and 2014. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) European Journal of Nutrition 59 7 3037 3044 |
institution |
Open Polar |
collection |
Umeå University: Publications (DiVA) |
op_collection_id |
ftumeauniv |
language |
English |
topic |
Vitamin D Trend Cross-sectional study MONICA Sweden Nutrition and Dietetics Näringslära |
spellingShingle |
Vitamin D Trend Cross-sectional study MONICA Sweden Nutrition and Dietetics Näringslära Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
topic_facet |
Vitamin D Trend Cross-sectional study MONICA Sweden Nutrition and Dietetics Näringslära |
description |
Purpose: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We examined the time trend of vitamin D concentrations in northern Sweden between 1986 and 2014. Methods: We used data on 11,129 men and women (aged 25–74 years) from seven population-based surveys (the Northern Sweden MONICA study), recruited between 1986 and 2014. Serum vitamin D (25-hydroxyvitamin D) status was measured using a one-step immunoassay (Abbott Architect). Multivariable linear regression models, adjusted for age, sex, and a number of other variables, were used to estimate the time trend of vitamin D concentrations. Results: The mean value of vitamin D in the entire study population was 19.9 ng/mL [standard deviation (SD) 7.9], with lower values in men (19.4 ng/mL; SD 7.5) than in women (20.5 ng/mL; SD 8.2). Using the survey in 1986 as reference category, the multivariable-adjusted mean difference [95% confidence interval (CI)] in ng/mL was 2.7 (2.2, 3.3) in 1990, 3.2 (2.7, 3.7) in 1994, 1.6 (1.0, 2.1) in 1999, − 2.0 (− 2.5, − 1.4) in 2004, 1.0 (0.4, 1.5) in 2009, and 3.1 (2.5, 3.6) in 2014. Conclusion: In this large cross-sectional study, we observed no clear upward or downward trend of vitamin D concentrations in northern Sweden between 1986 and 2014. |
format |
Article in Journal/Newspaper |
author |
Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor |
author_facet |
Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor |
author_sort |
Summerhays, Eva |
title |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
title_short |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
title_full |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
title_fullStr |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
title_full_unstemmed |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014 : a population-based cross-sectional study |
title_sort |
time trends of vitamin d concentrations in northern sweden between 1986 and 2014 : a population-based cross-sectional study |
publisher |
Umeå universitet, Avdelningen för medicin |
publishDate |
2020 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166576 https://doi.org/10.1007/s00394-019-02142-x |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
European Journal of Nutrition, 1436-6207, 2020, 59:7, s. 3037-3044 orcid:0000-0003-4059-3368 orcid:0000-0001-9225-1306 orcid:0000-0002-2936-2895 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166576 doi:10.1007/s00394-019-02142-x PMID 31754783 ISI:000497816400001 Scopus 2-s2.0-85075367003 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1007/s00394-019-02142-x |
container_title |
European Journal of Nutrition |
container_volume |
59 |
container_issue |
7 |
container_start_page |
3037 |
op_container_end_page |
3044 |
_version_ |
1810466494036836352 |