Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study

Dairy products are important constituents of most diets, and their association with adverse health outcomes remains a focus. We characterized dairy food intake and examined associations with the incidence of type 2 diabetes (T2D), myocardial infarction (MI) or stroke among 108,065 Swedish men and wo...

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Published in:Nutrients
Main Authors: Johansson, Ingegerd, Esberg, Anders, Nilsson, Lena Maria, Jansson, Jan-Håkan, Wennberg, Patrik, Winkvist, Anna
Format: Article in Journal/Newspaper
Language:English
Published: Umeå universitet, Institutionen för odontologi 2019
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156027
https://doi.org/10.3390/nu11020284
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spelling ftumeauniv:oai:DiVA.org:umu-156027 2023-10-09T21:54:34+02:00 Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study Johansson, Ingegerd Esberg, Anders Nilsson, Lena Maria Jansson, Jan-Håkan Wennberg, Patrik Winkvist, Anna 2019 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156027 https://doi.org/10.3390/nu11020284 eng eng Umeå universitet, Institutionen för odontologi Umeå universitet, Näringsforskning Umeå universitet, Avdelningen för medicin Umeå universitet, Allmänmedicin Department of Public Health and Clinical Medicine, Research Unit Skellefteå, Umeå University, 90187 Umeå, Sweden. Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden. Nutrients, 2019, 11:284, orcid:0000-0002-9227-8434 orcid:0000-0002-4430-8125 orcid:0000-0002-2354-7258 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156027 doi:10.3390/nu11020284 PMID 30696081 ISI:000460829700075 Scopus 2-s2.0-85060813708 info:eu-repo/semantics/openAccess dairy products milk cardiovascular disease myocardial infarction stroke type 2 diabetes Cardiac and Cardiovascular Systems Kardiologi Public Health Global Health Social Medicine and Epidemiology Folkhälsovetenskap global hälsa socialmedicin och epidemiologi Article in journal info:eu-repo/semantics/article text 2019 ftumeauniv https://doi.org/10.3390/nu11020284 2023-09-22T14:01:05Z Dairy products are important constituents of most diets, and their association with adverse health outcomes remains a focus. We characterized dairy food intake and examined associations with the incidence of type 2 diabetes (T2D), myocardial infarction (MI) or stroke among 108,065 Swedish men and women. Hazard ratios (HRs) and 95% CIs were estimated using the multivariable Cox proportional hazards models in a population characterized by high milk tolerance. During a mean follow-up of 14.2 years, 11,641 first-time events occurred. Non-fermented milk intake decreased, whereas butter intake increased over the period. For high intake of non-fermented milk, the HR (95% CI) for developing T2D and MI was 1.17 (1.03, 1.34) and 1.23 (1.10, 1.37), respectively, in men. A greater intake of butter, fermented milk, and cheese tended to be associated with a reduced risk of T2D and/or MI. Non-consumers and those who chose low-fat variants of the targeted dairy products had increased risk for T2D, MI, or stroke compared to those in the non-case group. Generally, effect-sizes were small. This prospective study found that non-fermented milk was associated with an increased risk for developing T2D and MI and that subjects abstaining from dairy products or choosing low-fat variants were at greater risk. However, the overall cardiometabolic risk of non-fermented milk intake was judged as low, since the effect sizes were small. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) Nutrients 11 2 284
institution Open Polar
collection Umeå University: Publications (DiVA)
op_collection_id ftumeauniv
language English
topic dairy products
milk
cardiovascular disease
myocardial infarction
stroke
type 2 diabetes
Cardiac and Cardiovascular Systems
Kardiologi
Public Health
Global Health
Social Medicine and Epidemiology
Folkhälsovetenskap
global hälsa
socialmedicin och epidemiologi
spellingShingle dairy products
milk
cardiovascular disease
myocardial infarction
stroke
type 2 diabetes
Cardiac and Cardiovascular Systems
Kardiologi
Public Health
Global Health
Social Medicine and Epidemiology
Folkhälsovetenskap
global hälsa
socialmedicin och epidemiologi
Johansson, Ingegerd
Esberg, Anders
Nilsson, Lena Maria
Jansson, Jan-Håkan
Wennberg, Patrik
Winkvist, Anna
Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
topic_facet dairy products
milk
cardiovascular disease
myocardial infarction
stroke
type 2 diabetes
Cardiac and Cardiovascular Systems
Kardiologi
Public Health
Global Health
Social Medicine and Epidemiology
Folkhälsovetenskap
global hälsa
socialmedicin och epidemiologi
description Dairy products are important constituents of most diets, and their association with adverse health outcomes remains a focus. We characterized dairy food intake and examined associations with the incidence of type 2 diabetes (T2D), myocardial infarction (MI) or stroke among 108,065 Swedish men and women. Hazard ratios (HRs) and 95% CIs were estimated using the multivariable Cox proportional hazards models in a population characterized by high milk tolerance. During a mean follow-up of 14.2 years, 11,641 first-time events occurred. Non-fermented milk intake decreased, whereas butter intake increased over the period. For high intake of non-fermented milk, the HR (95% CI) for developing T2D and MI was 1.17 (1.03, 1.34) and 1.23 (1.10, 1.37), respectively, in men. A greater intake of butter, fermented milk, and cheese tended to be associated with a reduced risk of T2D and/or MI. Non-consumers and those who chose low-fat variants of the targeted dairy products had increased risk for T2D, MI, or stroke compared to those in the non-case group. Generally, effect-sizes were small. This prospective study found that non-fermented milk was associated with an increased risk for developing T2D and MI and that subjects abstaining from dairy products or choosing low-fat variants were at greater risk. However, the overall cardiometabolic risk of non-fermented milk intake was judged as low, since the effect sizes were small.
format Article in Journal/Newspaper
author Johansson, Ingegerd
Esberg, Anders
Nilsson, Lena Maria
Jansson, Jan-Håkan
Wennberg, Patrik
Winkvist, Anna
author_facet Johansson, Ingegerd
Esberg, Anders
Nilsson, Lena Maria
Jansson, Jan-Håkan
Wennberg, Patrik
Winkvist, Anna
author_sort Johansson, Ingegerd
title Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
title_short Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
title_full Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
title_fullStr Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
title_full_unstemmed Dairy Product Intake and Cardiometabolic Diseases in Northern Sweden : A 33-Year Prospective Cohort Study
title_sort dairy product intake and cardiometabolic diseases in northern sweden : a 33-year prospective cohort study
publisher Umeå universitet, Institutionen för odontologi
publishDate 2019
url http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156027
https://doi.org/10.3390/nu11020284
genre Northern Sweden
genre_facet Northern Sweden
op_relation Nutrients, 2019, 11:284,
orcid:0000-0002-9227-8434
orcid:0000-0002-4430-8125
orcid:0000-0002-2354-7258
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156027
doi:10.3390/nu11020284
PMID 30696081
ISI:000460829700075
Scopus 2-s2.0-85060813708
op_rights info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.3390/nu11020284
container_title Nutrients
container_volume 11
container_issue 2
container_start_page 284
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