An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list
Purpose As people get older, their sensitivity to drugs and adverse drug reactions can increase due to pharmacokinetic and pharmacodynamic changes. Older people with dementia are a particularly vulnerable group of people. They are at an increased risk of being prescribed potentially inappropriate me...
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Language: | English |
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Umeå universitet, Farmakologi
2017
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ftumeauniv:oai:DiVA.org:umu-131328 2023-10-09T21:54:29+02:00 An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list Sönnerstam, Eva Sjölander, Maria Gustafsson, Maria 2017 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-131328 https://doi.org/10.1007/s00228-017-2218-2 eng eng Umeå universitet, Farmakologi European Journal of Clinical Pharmacology, 0031-6970, 2017, 73:6, s. 735-742 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-131328 doi:10.1007/s00228-017-2218-2 PMID 28246889 ISI:000400999200010 Scopus 2-s2.0-85014016241 info:eu-repo/semantics/openAccess Older people Cognitive impairment Potentially inappropriate medications EU(7)-PIM list Geriatrics Geriatrik Article in journal info:eu-repo/semantics/article text 2017 ftumeauniv https://doi.org/10.1007/s00228-017-2218-2 2023-09-22T13:58:34Z Purpose As people get older, their sensitivity to drugs and adverse drug reactions can increase due to pharmacokinetic and pharmacodynamic changes. Older people with dementia are a particularly vulnerable group of people. They are at an increased risk of being prescribed potentially inappropriate medications, which may lead to harmful consequences. The aim of this study was to investigate the prevalence of potentially inappropriate medications among older patients with cognitive impairment. Methods Medical records for patients aged ≥65 years admitted to two hospitals in Northern Sweden were reviewed. Potentially inappropriate medications were identified using the EU(7)-PIM list as an identification tool. Results Of 428 patients included in the study, 40.9% had one or more potentially inappropriate medication prescribed. The most commonly represented potentially inappropriate medication classes were hypnotics and sedatives, cardiovascular drugs and laxatives. The most commonly involved potentially inappropriate medications were zopiclone, digoxin and sodium picosulfate. There was an association seen between having a higher number of medications prescribed and having one or more potentially inappropriate medication. Conclusion Potentially inappropriate medications are prevalent among older people with cognitive impairment living in Northern Sweden. It is important to continuously evaluate the need for potentially inappropriate medications in this patient group, in order to prevent adverse drug reactions, especially among those who have a higher number of medications prescribed. Article in Journal/Newspaper Northern Sweden Umeå University: Publications (DiVA) European Journal of Clinical Pharmacology 73 6 735 742 |
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Umeå University: Publications (DiVA) |
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ftumeauniv |
language |
English |
topic |
Older people Cognitive impairment Potentially inappropriate medications EU(7)-PIM list Geriatrics Geriatrik |
spellingShingle |
Older people Cognitive impairment Potentially inappropriate medications EU(7)-PIM list Geriatrics Geriatrik Sönnerstam, Eva Sjölander, Maria Gustafsson, Maria An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
topic_facet |
Older people Cognitive impairment Potentially inappropriate medications EU(7)-PIM list Geriatrics Geriatrik |
description |
Purpose As people get older, their sensitivity to drugs and adverse drug reactions can increase due to pharmacokinetic and pharmacodynamic changes. Older people with dementia are a particularly vulnerable group of people. They are at an increased risk of being prescribed potentially inappropriate medications, which may lead to harmful consequences. The aim of this study was to investigate the prevalence of potentially inappropriate medications among older patients with cognitive impairment. Methods Medical records for patients aged ≥65 years admitted to two hospitals in Northern Sweden were reviewed. Potentially inappropriate medications were identified using the EU(7)-PIM list as an identification tool. Results Of 428 patients included in the study, 40.9% had one or more potentially inappropriate medication prescribed. The most commonly represented potentially inappropriate medication classes were hypnotics and sedatives, cardiovascular drugs and laxatives. The most commonly involved potentially inappropriate medications were zopiclone, digoxin and sodium picosulfate. There was an association seen between having a higher number of medications prescribed and having one or more potentially inappropriate medication. Conclusion Potentially inappropriate medications are prevalent among older people with cognitive impairment living in Northern Sweden. It is important to continuously evaluate the need for potentially inappropriate medications in this patient group, in order to prevent adverse drug reactions, especially among those who have a higher number of medications prescribed. |
format |
Article in Journal/Newspaper |
author |
Sönnerstam, Eva Sjölander, Maria Gustafsson, Maria |
author_facet |
Sönnerstam, Eva Sjölander, Maria Gustafsson, Maria |
author_sort |
Sönnerstam, Eva |
title |
An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
title_short |
An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
title_full |
An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
title_fullStr |
An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
title_full_unstemmed |
An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list |
title_sort |
evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in northern sweden using the eu(7)-pim list |
publisher |
Umeå universitet, Farmakologi |
publishDate |
2017 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-131328 https://doi.org/10.1007/s00228-017-2218-2 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
European Journal of Clinical Pharmacology, 0031-6970, 2017, 73:6, s. 735-742 http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-131328 doi:10.1007/s00228-017-2218-2 PMID 28246889 ISI:000400999200010 Scopus 2-s2.0-85014016241 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1007/s00228-017-2218-2 |
container_title |
European Journal of Clinical Pharmacology |
container_volume |
73 |
container_issue |
6 |
container_start_page |
735 |
op_container_end_page |
742 |
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1779318069854732288 |