Interorgan ammonia, glutamate and glutamine trafficking in pigs with acute liver failure

• Published in: American Journal of Physiology-Gastrointestinal and Liver Physiology
• Main Authors: Ytrebo, L.M., Sen, S., Rose, C., ten Have, G.A.M., Davies, N.A., Hodges, S., Nedredal, G.I., Romero-Gomez, M., Williams, R., Revhaug, A., Jalan, R., Deutz, N.E.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2006
• Subjects: Norway; Gomez; Alf; The Portal; Romero; Nedredal; Northern Norway
• Online Access: https://cris.maastrichtuniversity.nl/en/publications/c0bf6b66-4ecb-4a83-91dc-5e179d01035a; https://doi.org/10.1152/ajpgi.00440.2005

Background/Aims: Ammonia reduction is the target for therapy of hepatic encephalopathy (HE) but lack of quantitative data about how the individual organs handle ammonia limit our ability to develop novel therapeutic strategies. The study aims were to evaluate interorgan ammonia metabolism quantitati...