Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.)
The distribution of the neuropeptides methionine‐ and leucine‐enkephalins, substance P, FMRFamide, neuropeptide Y, and vasoactive intestinal peptide, as well as the biogenic amine serotonin was studied in the optic tectum of the Atlantic salmon by means of immunocytochemistry. Peroxidase‐antiperoxid...
Published in: | The Journal of Comparative Neurology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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John Wiley & Sons Inc.
1990
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Online Access: | https://lup.lub.lu.se/record/f500e251-adf2-440f-b958-be73260c35e7 https://doi.org/10.1002/cne.902990207 |
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ftulundlup:oai:lup.lub.lu.se:f500e251-adf2-440f-b958-be73260c35e7 2024-01-28T10:04:32+01:00 Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) Vecino, Elena Ekström, Peter 1990-01-01 https://lup.lub.lu.se/record/f500e251-adf2-440f-b958-be73260c35e7 https://doi.org/10.1002/cne.902990207 eng eng John Wiley & Sons Inc. https://lup.lub.lu.se/record/f500e251-adf2-440f-b958-be73260c35e7 http://dx.doi.org/10.1002/cne.902990207 pmid:2229479 scopus:0025036067 Journal of Comparative Neurology; 299(2), pp 229-241 (1990) ISSN: 0021-9967 Neurosciences immunocytochemistry mesencephalon neurotransmitters Teleostei contributiontojournal/article info:eu-repo/semantics/article text 1990 ftulundlup https://doi.org/10.1002/cne.902990207 2024-01-03T23:29:17Z The distribution of the neuropeptides methionine‐ and leucine‐enkephalins, substance P, FMRFamide, neuropeptide Y, and vasoactive intestinal peptide, as well as the biogenic amine serotonin was studied in the optic tectum of the Atlantic salmon by means of immunocytochemistry. Peroxidase‐antiperoxidase and indirect immunofluorescence methods were used to compare the differential laminar distribution of each of these substances. Nine parts of the optic tectum were selected for analysis on frontal sections: median, dorsolateral, and ventrolateral areas at rostral, medial, and caudal levels. Methionine‐ and leucine‐enkephalin immunoreactive fibers were found in discrete sublayers in the following strata: stratum opticum, stratum fibrosum et griseum superficiale, stratum griseum centrale, stratum, and album centrale. Most of the substance P‐, serotonin‐, and vasoactive intestinal peptide‐immunoreactive fibers were found in the stratum album centrale, whereas the FMRFamide‐ and neuropeptide Y‐immunoreactive fibers were more or less randomly distributed within most of the strata of the optic tectum. Neuropeptide Y‐immunoreactive cell bodies were located in the stratum periventriculare. We suggest an extrinsic origin for most of the immunoreactive fibers observed in the optic tectum, except for the neuropeptide Y‐immunoreactive fibers that probably originate in the periventricular neurons. Although retinal peptidergic input to the optic tectum has been proposed in other vertebrates, there is no evidence that any of the neuropeptidelike or serotonin immunoreactive fibers in the optic tectum of the salmon should be of retinal origin. Differences and similarities with the distribution of neuropeptides in the optic tectum in representatives of other vertebrate classes are discussed. Article in Journal/Newspaper Atlantic salmon Salmo salar Lund University Publications (LUP) The Journal of Comparative Neurology 299 2 229 241 |
institution |
Open Polar |
collection |
Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
English |
topic |
Neurosciences immunocytochemistry mesencephalon neurotransmitters Teleostei |
spellingShingle |
Neurosciences immunocytochemistry mesencephalon neurotransmitters Teleostei Vecino, Elena Ekström, Peter Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
topic_facet |
Neurosciences immunocytochemistry mesencephalon neurotransmitters Teleostei |
description |
The distribution of the neuropeptides methionine‐ and leucine‐enkephalins, substance P, FMRFamide, neuropeptide Y, and vasoactive intestinal peptide, as well as the biogenic amine serotonin was studied in the optic tectum of the Atlantic salmon by means of immunocytochemistry. Peroxidase‐antiperoxidase and indirect immunofluorescence methods were used to compare the differential laminar distribution of each of these substances. Nine parts of the optic tectum were selected for analysis on frontal sections: median, dorsolateral, and ventrolateral areas at rostral, medial, and caudal levels. Methionine‐ and leucine‐enkephalin immunoreactive fibers were found in discrete sublayers in the following strata: stratum opticum, stratum fibrosum et griseum superficiale, stratum griseum centrale, stratum, and album centrale. Most of the substance P‐, serotonin‐, and vasoactive intestinal peptide‐immunoreactive fibers were found in the stratum album centrale, whereas the FMRFamide‐ and neuropeptide Y‐immunoreactive fibers were more or less randomly distributed within most of the strata of the optic tectum. Neuropeptide Y‐immunoreactive cell bodies were located in the stratum periventriculare. We suggest an extrinsic origin for most of the immunoreactive fibers observed in the optic tectum, except for the neuropeptide Y‐immunoreactive fibers that probably originate in the periventricular neurons. Although retinal peptidergic input to the optic tectum has been proposed in other vertebrates, there is no evidence that any of the neuropeptidelike or serotonin immunoreactive fibers in the optic tectum of the salmon should be of retinal origin. Differences and similarities with the distribution of neuropeptides in the optic tectum in representatives of other vertebrate classes are discussed. |
format |
Article in Journal/Newspaper |
author |
Vecino, Elena Ekström, Peter |
author_facet |
Vecino, Elena Ekström, Peter |
author_sort |
Vecino, Elena |
title |
Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
title_short |
Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
title_full |
Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
title_fullStr |
Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
title_full_unstemmed |
Distribution of met‐enkephalin, leu‐enkephalin, substance P, neuropeptide Y, FMRFamide, and serotonin immunoreactivities in the optic tectum of the Atlantic salmon (Salmo salar L.) |
title_sort |
distribution of met‐enkephalin, leu‐enkephalin, substance p, neuropeptide y, fmrfamide, and serotonin immunoreactivities in the optic tectum of the atlantic salmon (salmo salar l.) |
publisher |
John Wiley & Sons Inc. |
publishDate |
1990 |
url |
https://lup.lub.lu.se/record/f500e251-adf2-440f-b958-be73260c35e7 https://doi.org/10.1002/cne.902990207 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Journal of Comparative Neurology; 299(2), pp 229-241 (1990) ISSN: 0021-9967 |
op_relation |
https://lup.lub.lu.se/record/f500e251-adf2-440f-b958-be73260c35e7 http://dx.doi.org/10.1002/cne.902990207 pmid:2229479 scopus:0025036067 |
op_doi |
https://doi.org/10.1002/cne.902990207 |
container_title |
The Journal of Comparative Neurology |
container_volume |
299 |
container_issue |
2 |
container_start_page |
229 |
op_container_end_page |
241 |
_version_ |
1789330276407574528 |