Immune function and organochlorine pollutants in arctic breeding glaucous gulls
Organochlorine contaminants (OCs) are known to affect the immune systems of wildlife, and in this study we assessed the relationship between blood concentration of different OCs and measurements relevant to immune status and function in arctic breeding glaucous gulls (Larus hyperboreus). In 1997 and...
Published in: | Archives of Environmental Contamination and Toxicology |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Springer
2004
|
Subjects: | |
Online Access: | https://lup.lub.lu.se/record/145180 https://doi.org/10.1007/s00244-003-3203-6 https://portal.research.lu.se/files/2640753/625040.pdf |
id |
ftulundlup:oai:lup.lub.lu.se:ef0228cf-0266-4f9d-9f76-0ead28175363 |
---|---|
record_format |
openpolar |
spelling |
ftulundlup:oai:lup.lub.lu.se:ef0228cf-0266-4f9d-9f76-0ead28175363 2023-05-15T14:59:55+02:00 Immune function and organochlorine pollutants in arctic breeding glaucous gulls Bustnes, JO Hanssen, SA Folstad, I Erikstad, KE Hasselquist, Dennis Skaare, JU 2004 application/pdf https://lup.lub.lu.se/record/145180 https://doi.org/10.1007/s00244-003-3203-6 https://portal.research.lu.se/files/2640753/625040.pdf eng eng Springer https://lup.lub.lu.se/record/145180 http://dx.doi.org/10.1007/s00244-003-3203-6 https://portal.research.lu.se/files/2640753/625040.pdf pmid:15499504 wos:000224753800013 scopus:7944235838 info:eu-repo/semantics/openAccess Archives of Environmental Contamination and Toxicology; 47(4), pp 530-541 (2004) ISSN: 0090-4341 Biological Sciences contributiontojournal/article info:eu-repo/semantics/article text 2004 ftulundlup https://doi.org/10.1007/s00244-003-3203-6 2023-02-01T23:28:46Z Organochlorine contaminants (OCs) are known to affect the immune systems of wildlife, and in this study we assessed the relationship between blood concentration of different OCs and measurements relevant to immune status and function in arctic breeding glaucous gulls (Larus hyperboreus). In 1997 and 2001, we counted white blood cells (heterophils and lymphocytes) from blood smears, and in 2000 and 2001 we injected two novel nonpathogenic antigens (diphtheria and tetanus toxoids) into the pectoral muscle of gulls and measured the primary antibody responses. We then related these measurements to the blood concentrations of three pesticides (hexachlorobenzene [HCB], oxychlordane, and p,p'-dichlorodiphenyldichloroethylene) and seven different polychlorinated biphenyl congeners (PCB 101, 99, 118, 153, 138, 180, and 170). There were significant or near significant positive relationships (0.1 > p > 0.001) between most persistent OCs and the levels of heterophils in the blood for both sexes in 1997 and for male gulls in 2001. Similarly, levels of all persistent OCs and lymphocytes were positively related (0.1 > p > 0.001) in both sexes in 1997. This suggests that OCs are causing alterations to immune systems, which may decrease their efficiency and make the birds more susceptible to parasites and diseases. In female gulls, the antibody response to the diphtheria toxoid was significant and negative for HCB (p <0.01) and weaker, but significant, for oxychlordane (p <0.05), suggesting that OCs were causing an impairment of the humoral immunity. Various OCs have been linked to negative effects in our study population, including decreased survival and reproduction, and this study suggests that such compounds also affect immune status and function. Article in Journal/Newspaper Arctic Larus hyperboreus Lund University Publications (LUP) Arctic Archives of Environmental Contamination and Toxicology 47 4 530 541 |
institution |
Open Polar |
collection |
Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
English |
topic |
Biological Sciences |
spellingShingle |
Biological Sciences Bustnes, JO Hanssen, SA Folstad, I Erikstad, KE Hasselquist, Dennis Skaare, JU Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
topic_facet |
Biological Sciences |
description |
Organochlorine contaminants (OCs) are known to affect the immune systems of wildlife, and in this study we assessed the relationship between blood concentration of different OCs and measurements relevant to immune status and function in arctic breeding glaucous gulls (Larus hyperboreus). In 1997 and 2001, we counted white blood cells (heterophils and lymphocytes) from blood smears, and in 2000 and 2001 we injected two novel nonpathogenic antigens (diphtheria and tetanus toxoids) into the pectoral muscle of gulls and measured the primary antibody responses. We then related these measurements to the blood concentrations of three pesticides (hexachlorobenzene [HCB], oxychlordane, and p,p'-dichlorodiphenyldichloroethylene) and seven different polychlorinated biphenyl congeners (PCB 101, 99, 118, 153, 138, 180, and 170). There were significant or near significant positive relationships (0.1 > p > 0.001) between most persistent OCs and the levels of heterophils in the blood for both sexes in 1997 and for male gulls in 2001. Similarly, levels of all persistent OCs and lymphocytes were positively related (0.1 > p > 0.001) in both sexes in 1997. This suggests that OCs are causing alterations to immune systems, which may decrease their efficiency and make the birds more susceptible to parasites and diseases. In female gulls, the antibody response to the diphtheria toxoid was significant and negative for HCB (p <0.01) and weaker, but significant, for oxychlordane (p <0.05), suggesting that OCs were causing an impairment of the humoral immunity. Various OCs have been linked to negative effects in our study population, including decreased survival and reproduction, and this study suggests that such compounds also affect immune status and function. |
format |
Article in Journal/Newspaper |
author |
Bustnes, JO Hanssen, SA Folstad, I Erikstad, KE Hasselquist, Dennis Skaare, JU |
author_facet |
Bustnes, JO Hanssen, SA Folstad, I Erikstad, KE Hasselquist, Dennis Skaare, JU |
author_sort |
Bustnes, JO |
title |
Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
title_short |
Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
title_full |
Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
title_fullStr |
Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
title_full_unstemmed |
Immune function and organochlorine pollutants in arctic breeding glaucous gulls |
title_sort |
immune function and organochlorine pollutants in arctic breeding glaucous gulls |
publisher |
Springer |
publishDate |
2004 |
url |
https://lup.lub.lu.se/record/145180 https://doi.org/10.1007/s00244-003-3203-6 https://portal.research.lu.se/files/2640753/625040.pdf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Larus hyperboreus |
genre_facet |
Arctic Larus hyperboreus |
op_source |
Archives of Environmental Contamination and Toxicology; 47(4), pp 530-541 (2004) ISSN: 0090-4341 |
op_relation |
https://lup.lub.lu.se/record/145180 http://dx.doi.org/10.1007/s00244-003-3203-6 https://portal.research.lu.se/files/2640753/625040.pdf pmid:15499504 wos:000224753800013 scopus:7944235838 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1007/s00244-003-3203-6 |
container_title |
Archives of Environmental Contamination and Toxicology |
container_volume |
47 |
container_issue |
4 |
container_start_page |
530 |
op_container_end_page |
541 |
_version_ |
1766332041719185408 |