Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden.
Atlantic salmon accumulate high levels of contaminants such as polychlorinated biphenyls (PCBs) in their lipids during the adult growth phase spent at sea. The lipids are later utilized during migration for swimming and biological adaptations. We hypothesize that migrating salmons' biotransform...
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Online Access: | https://lup.lub.lu.se/record/1452980 https://doi.org/10.1016/j.envpol.2009.06.026 |
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ftulundlup:oai:lup.lub.lu.se:bc060515-3521-4e5e-a03c-34193408ec57 2023-05-15T15:30:41+02:00 Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. Hansson, Maria Persson, Maria Larsson, Per von Schantz, Torbjörn 2009 https://lup.lub.lu.se/record/1452980 https://doi.org/10.1016/j.envpol.2009.06.026 eng eng Elsevier https://lup.lub.lu.se/record/1452980 http://dx.doi.org/10.1016/j.envpol.2009.06.026 wos:000272334500029 scopus:74249108239 pmid:19616879 Environmental Pollution; 157(12), pp 3396-3403 (2009) ISSN: 0269-7491 Biological Sciences Ecology Earth and Related Environmental Sciences contributiontojournal/article info:eu-repo/semantics/article text 2009 ftulundlup https://doi.org/10.1016/j.envpol.2009.06.026 2023-02-01T23:32:41Z Atlantic salmon accumulate high levels of contaminants such as polychlorinated biphenyls (PCBs) in their lipids during the adult growth phase spent at sea. The lipids are later utilized during migration for swimming and biological adaptations. We hypothesize that migrating salmons' biotransformation processes are affected by the high levels of built-up PCBs compared to salmon that in a pre-migrational stage. For these analyses we sampled adult Atlantic salmon during migration in the Swedish River Mörrum and measured the 21 most common PCB congeners ( summation operatorPCB) and lipid levels in muscle tissue, aryl hydrocarbon receptor (AHR2) and cytochrome P4501A1 (CYP1A1) transcript levels as well as ethoxyresorufin-O-deethylase activity (EROD) in liver. We also determined which AHR2 genotypes the salmon carried. We show that EROD activity is correlated to CYP1A1 level but not to summation operatorPCB concentration. summation operatorPCB concentration does not predict levels of neither the AHR2 nor CYP1A1 genes. We find no associations between specific AHR2 transcription levels and AHR2 genotypes or a correlation between AHR2 and CYP1A1 transcription levels, which is in direct contrast to pre-migrational adult salmon from the Baltic Sea. When we compare River Mörrum to salmon we have previously sampled in the Baltic Sea we show that migrating salmon have significantly lower lipid levels in their muscles; higher muscle concentrations of summation operatorPCB on a lipid basis; and significantly lower CYP1A1 and EROD levels compared to salmon from the Baltic Sea. Also, transcript levels of three out of four AHR2 genes are significantly different. In conclusion, migrating Swedish Atlantic salmon carry higher concentrations of PCBs in their lipids compared to salmon in the Baltic Sea, but have lower activation of biotransformation genes and enzymes. Our results indicate that accumulated pollutants from the Baltic Sea are deactivated inside the migrating salmon's lipid tissues and increase in concentration when ... Article in Journal/Newspaper Atlantic salmon Lund University Publications (LUP) Environmental Pollution 157 12 3396 3403 |
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Open Polar |
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Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
English |
topic |
Biological Sciences Ecology Earth and Related Environmental Sciences |
spellingShingle |
Biological Sciences Ecology Earth and Related Environmental Sciences Hansson, Maria Persson, Maria Larsson, Per von Schantz, Torbjörn Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
topic_facet |
Biological Sciences Ecology Earth and Related Environmental Sciences |
description |
Atlantic salmon accumulate high levels of contaminants such as polychlorinated biphenyls (PCBs) in their lipids during the adult growth phase spent at sea. The lipids are later utilized during migration for swimming and biological adaptations. We hypothesize that migrating salmons' biotransformation processes are affected by the high levels of built-up PCBs compared to salmon that in a pre-migrational stage. For these analyses we sampled adult Atlantic salmon during migration in the Swedish River Mörrum and measured the 21 most common PCB congeners ( summation operatorPCB) and lipid levels in muscle tissue, aryl hydrocarbon receptor (AHR2) and cytochrome P4501A1 (CYP1A1) transcript levels as well as ethoxyresorufin-O-deethylase activity (EROD) in liver. We also determined which AHR2 genotypes the salmon carried. We show that EROD activity is correlated to CYP1A1 level but not to summation operatorPCB concentration. summation operatorPCB concentration does not predict levels of neither the AHR2 nor CYP1A1 genes. We find no associations between specific AHR2 transcription levels and AHR2 genotypes or a correlation between AHR2 and CYP1A1 transcription levels, which is in direct contrast to pre-migrational adult salmon from the Baltic Sea. When we compare River Mörrum to salmon we have previously sampled in the Baltic Sea we show that migrating salmon have significantly lower lipid levels in their muscles; higher muscle concentrations of summation operatorPCB on a lipid basis; and significantly lower CYP1A1 and EROD levels compared to salmon from the Baltic Sea. Also, transcript levels of three out of four AHR2 genes are significantly different. In conclusion, migrating Swedish Atlantic salmon carry higher concentrations of PCBs in their lipids compared to salmon in the Baltic Sea, but have lower activation of biotransformation genes and enzymes. Our results indicate that accumulated pollutants from the Baltic Sea are deactivated inside the migrating salmon's lipid tissues and increase in concentration when ... |
format |
Article in Journal/Newspaper |
author |
Hansson, Maria Persson, Maria Larsson, Per von Schantz, Torbjörn |
author_facet |
Hansson, Maria Persson, Maria Larsson, Per von Schantz, Torbjörn |
author_sort |
Hansson, Maria |
title |
Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
title_short |
Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
title_full |
Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
title_fullStr |
Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
title_full_unstemmed |
Polychlorinated biphenyl (PCB) load, lipid reserves and biotransformation activity in migrating Atlantic salmon from River Mörrum, Sweden. |
title_sort |
polychlorinated biphenyl (pcb) load, lipid reserves and biotransformation activity in migrating atlantic salmon from river mörrum, sweden. |
publisher |
Elsevier |
publishDate |
2009 |
url |
https://lup.lub.lu.se/record/1452980 https://doi.org/10.1016/j.envpol.2009.06.026 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Environmental Pollution; 157(12), pp 3396-3403 (2009) ISSN: 0269-7491 |
op_relation |
https://lup.lub.lu.se/record/1452980 http://dx.doi.org/10.1016/j.envpol.2009.06.026 wos:000272334500029 scopus:74249108239 pmid:19616879 |
op_doi |
https://doi.org/10.1016/j.envpol.2009.06.026 |
container_title |
Environmental Pollution |
container_volume |
157 |
container_issue |
12 |
container_start_page |
3396 |
op_container_end_page |
3403 |
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1766361142929653760 |