Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi
OBJECTIVES: Degenerative mitral valve disease is the most common indication for mitral valve repair in the Western world. The aim of this study was to study the long term outcome of mitral valve repair for degenerative mitral valve regurgitation in Iceland. MATERIAL AND METHODS: A retrospective stud...
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Format: | Article in Journal/Newspaper |
Language: | Icelandic |
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Læknafélag Íslands, Læknafélag Reykjavíkur
2021
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Online Access: | https://lup.lub.lu.se/record/46a61a3e-c951-410c-940e-0a84ec611d40 https://doi.org/10.17992/lbl.2021.06.639 |
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ftulundlup:oai:lup.lub.lu.se:46a61a3e-c951-410c-940e-0a84ec611d40 2024-04-21T08:05:30+00:00 Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi Steinþórsson, Árni Steinn Johnsen, Árni Sigurðsson, Martin Ingi Ragnarsson, Sigurður Guðbjartsson, Tómas 2021 https://lup.lub.lu.se/record/46a61a3e-c951-410c-940e-0a84ec611d40 https://doi.org/10.17992/lbl.2021.06.639 ice ice Læknafélag Íslands, Læknafélag Reykjavíkur https://lup.lub.lu.se/record/46a61a3e-c951-410c-940e-0a84ec611d40 http://dx.doi.org/10.17992/lbl.2021.06.639 scopus:85107239003 pmid:34057075 Laeknabladid; 107(6), pp 279-286 (2021) ISSN: 0023-7213 Cardiac and Cardiovascular Systems Complications Degenerative mitral valve disease Mitral valve plasticity Mitral valve repair Outcome Survival contributiontojournal/article info:eu-repo/semantics/article text 2021 ftulundlup https://doi.org/10.17992/lbl.2021.06.639 2024-03-27T15:09:11Z OBJECTIVES: Degenerative mitral valve disease is the most common indication for mitral valve repair in the Western world. The aim of this study was to study the long term outcome of mitral valve repair for degenerative mitral valve regurgitation in Iceland. MATERIAL AND METHODS: A retrospective study of 101 consecutive mitral valve repair patients (average age 57.7 years, 80.2% male) operated in Iceland 2004-2018 for degenerative mitral valve regurgitation. Long term survival and MACCE (major adverse cardiac and cerebrovascular event) free survival was estimated using the Kaplan-Meier method and compared to age and gender matched reference population. Median follow-up time was 83 months. RESULTS: On average there were 6,7 (range 1-14) mitral valve repairs performed annually with 99% of the patients receiving ring annuloplasty. A total of 82 (82,2%) underwent resection of the posterior leaflet and 64.4% recieved Gore-TexR-chordae. Major early complications occured in 28.7% of cases, most commonly perioperative myocardial infarction (11.9%) and reoperation for bleeding (8.9%). Mortality within 30 days was 2%, the median duration of intensive care unit stay was one day and the median hospital length of stay was 8 days. One patient needed reoperation later for recurrent mitral regurgitation. Five and ten year MACCEfree survival was 91.1% (95%-CI: 85.3-97.2) and 81.0 (95%-CI: 71.6-91.6), respectively. Five year survival was 93.5% (95-CI: 88.6-98.7) and 10 year survival 85.3% (95%-CI: 76.6-94.9), which was not different from an age and gender matched reference population (p=0.135, log-rank test). CONCLUSION: Outcomes of mitral valve repair due to degenerative mitral regurgitation is good in Iceland and results are comparable to larger institutions overseas. Long term prognosis is generally good although early postoperative complications often occur. Article in Journal/Newspaper Iceland Lund University Publications (LUP) Læknablaðið 107 o6 279 286 |
institution |
Open Polar |
collection |
Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
Icelandic |
topic |
Cardiac and Cardiovascular Systems Complications Degenerative mitral valve disease Mitral valve plasticity Mitral valve repair Outcome Survival |
spellingShingle |
Cardiac and Cardiovascular Systems Complications Degenerative mitral valve disease Mitral valve plasticity Mitral valve repair Outcome Survival Steinþórsson, Árni Steinn Johnsen, Árni Sigurðsson, Martin Ingi Ragnarsson, Sigurður Guðbjartsson, Tómas Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
topic_facet |
Cardiac and Cardiovascular Systems Complications Degenerative mitral valve disease Mitral valve plasticity Mitral valve repair Outcome Survival |
description |
OBJECTIVES: Degenerative mitral valve disease is the most common indication for mitral valve repair in the Western world. The aim of this study was to study the long term outcome of mitral valve repair for degenerative mitral valve regurgitation in Iceland. MATERIAL AND METHODS: A retrospective study of 101 consecutive mitral valve repair patients (average age 57.7 years, 80.2% male) operated in Iceland 2004-2018 for degenerative mitral valve regurgitation. Long term survival and MACCE (major adverse cardiac and cerebrovascular event) free survival was estimated using the Kaplan-Meier method and compared to age and gender matched reference population. Median follow-up time was 83 months. RESULTS: On average there were 6,7 (range 1-14) mitral valve repairs performed annually with 99% of the patients receiving ring annuloplasty. A total of 82 (82,2%) underwent resection of the posterior leaflet and 64.4% recieved Gore-TexR-chordae. Major early complications occured in 28.7% of cases, most commonly perioperative myocardial infarction (11.9%) and reoperation for bleeding (8.9%). Mortality within 30 days was 2%, the median duration of intensive care unit stay was one day and the median hospital length of stay was 8 days. One patient needed reoperation later for recurrent mitral regurgitation. Five and ten year MACCEfree survival was 91.1% (95%-CI: 85.3-97.2) and 81.0 (95%-CI: 71.6-91.6), respectively. Five year survival was 93.5% (95-CI: 88.6-98.7) and 10 year survival 85.3% (95%-CI: 76.6-94.9), which was not different from an age and gender matched reference population (p=0.135, log-rank test). CONCLUSION: Outcomes of mitral valve repair due to degenerative mitral regurgitation is good in Iceland and results are comparable to larger institutions overseas. Long term prognosis is generally good although early postoperative complications often occur. |
format |
Article in Journal/Newspaper |
author |
Steinþórsson, Árni Steinn Johnsen, Árni Sigurðsson, Martin Ingi Ragnarsson, Sigurður Guðbjartsson, Tómas |
author_facet |
Steinþórsson, Árni Steinn Johnsen, Árni Sigurðsson, Martin Ingi Ragnarsson, Sigurður Guðbjartsson, Tómas |
author_sort |
Steinþórsson, Árni Steinn |
title |
Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
title_short |
Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
title_full |
Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
title_fullStr |
Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
title_full_unstemmed |
Langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á Íslandi |
title_sort |
langtímaárangur viðgerða vegna hrörnunartengds míturlokuleka á íslandi |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2021 |
url |
https://lup.lub.lu.se/record/46a61a3e-c951-410c-940e-0a84ec611d40 https://doi.org/10.17992/lbl.2021.06.639 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Laeknabladid; 107(6), pp 279-286 (2021) ISSN: 0023-7213 |
op_relation |
https://lup.lub.lu.se/record/46a61a3e-c951-410c-940e-0a84ec611d40 http://dx.doi.org/10.17992/lbl.2021.06.639 scopus:85107239003 pmid:34057075 |
op_doi |
https://doi.org/10.17992/lbl.2021.06.639 |
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Læknablaðið |
container_volume |
107 |
container_issue |
o6 |
container_start_page |
279 |
op_container_end_page |
286 |
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1796944988563570688 |