Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird
Animals in seasonal environments must prudently manage energyexpenditure to survive the winter. This may be achieved throughreductions in the allocation of energy for various purposes (e.g.thermoregulation, locomotion, etc.). We studied whether such tradeoffsalso include suppression of the innate im...
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Language: | English |
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The Company of Biologists Ltd
2020
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Online Access: | https://lup.lub.lu.se/record/17e57296-9ef7-49c9-a268-0052bf2037e8 https://doi.org/10.1242/jeb.219287 |
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ftulundlup:oai:lup.lub.lu.se:17e57296-9ef7-49c9-a268-0052bf2037e8 2023-05-15T14:53:33+02:00 Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird Nord, Andreas Hegemann, Arne Folkow, Lars P. 2020 https://lup.lub.lu.se/record/17e57296-9ef7-49c9-a268-0052bf2037e8 https://doi.org/10.1242/jeb.219287 eng eng The Company of Biologists Ltd https://lup.lub.lu.se/record/17e57296-9ef7-49c9-a268-0052bf2037e8 http://dx.doi.org/10.1242/jeb.219287 pmid:32341183 scopus:85085255627 Journal of Experimental Biology; 223(8), no jeb219287 (2020) ISSN: 1477-9145 Ecology Immunology Zoology immune function thermoregulation bird winter season Arctic polar immune response anorexia contributiontojournal/article info:eu-repo/semantics/article text 2020 ftulundlup https://doi.org/10.1242/jeb.219287 2023-02-01T23:39:45Z Animals in seasonal environments must prudently manage energyexpenditure to survive the winter. This may be achieved throughreductions in the allocation of energy for various purposes (e.g.thermoregulation, locomotion, etc.). We studied whether such tradeoffsalso include suppression of the innate immune response, bysubjecting captive male Svalbard ptarmigan (Lagopus mutahyperborea) to bacterial lipopolysaccharide (LPS) during exposureto either mild temperature (0°C) or cold snaps (acute exposure to−20°C), in constant winter darkness when birds were in energyconservingmode, and in constant daylight in spring. The innateimmune response was mostly unaffected by temperature. However,energy expenditure was below baseline when birds were immunechallenged in winter, but significantly above baseline in spring. Thissuggests that the energetic component of the innate immuneresponse was reduced in winter, possibly contributing to energyconservation. Immunological parameters decreased (agglutination,lysis, bacteriostatic capacity) or did not change (haptoglobin/PIT54)after the challenge, and behavioural modifications (anorexia, massloss) were lengthy (9 days). While we did not study the mechanismsexplaining these weak, or slow, responses, it is tempting to speculatethey may reflect the consequences of having evolved in anenvironment where pathogen transmission rate is presumably lowfor most of the year. This is an important consideration if climatechange and increased exploitation of the Arctic would alter pathogencommunities at a pace outwith counter-adaption in wildlife. Article in Journal/Newspaper Arctic Svalbard Lund University Publications (LUP) Arctic Svalbard Journal of Experimental Biology 223 8 |
institution |
Open Polar |
collection |
Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
English |
topic |
Ecology Immunology Zoology immune function thermoregulation bird winter season Arctic polar immune response anorexia |
spellingShingle |
Ecology Immunology Zoology immune function thermoregulation bird winter season Arctic polar immune response anorexia Nord, Andreas Hegemann, Arne Folkow, Lars P. Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
topic_facet |
Ecology Immunology Zoology immune function thermoregulation bird winter season Arctic polar immune response anorexia |
description |
Animals in seasonal environments must prudently manage energyexpenditure to survive the winter. This may be achieved throughreductions in the allocation of energy for various purposes (e.g.thermoregulation, locomotion, etc.). We studied whether such tradeoffsalso include suppression of the innate immune response, bysubjecting captive male Svalbard ptarmigan (Lagopus mutahyperborea) to bacterial lipopolysaccharide (LPS) during exposureto either mild temperature (0°C) or cold snaps (acute exposure to−20°C), in constant winter darkness when birds were in energyconservingmode, and in constant daylight in spring. The innateimmune response was mostly unaffected by temperature. However,energy expenditure was below baseline when birds were immunechallenged in winter, but significantly above baseline in spring. Thissuggests that the energetic component of the innate immuneresponse was reduced in winter, possibly contributing to energyconservation. Immunological parameters decreased (agglutination,lysis, bacteriostatic capacity) or did not change (haptoglobin/PIT54)after the challenge, and behavioural modifications (anorexia, massloss) were lengthy (9 days). While we did not study the mechanismsexplaining these weak, or slow, responses, it is tempting to speculatethey may reflect the consequences of having evolved in anenvironment where pathogen transmission rate is presumably lowfor most of the year. This is an important consideration if climatechange and increased exploitation of the Arctic would alter pathogencommunities at a pace outwith counter-adaption in wildlife. |
format |
Article in Journal/Newspaper |
author |
Nord, Andreas Hegemann, Arne Folkow, Lars P. |
author_facet |
Nord, Andreas Hegemann, Arne Folkow, Lars P. |
author_sort |
Nord, Andreas |
title |
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
title_short |
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
title_full |
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
title_fullStr |
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
title_full_unstemmed |
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird |
title_sort |
reduced immune responsiveness contributes to winter energy conservation in an arctic bird |
publisher |
The Company of Biologists Ltd |
publishDate |
2020 |
url |
https://lup.lub.lu.se/record/17e57296-9ef7-49c9-a268-0052bf2037e8 https://doi.org/10.1242/jeb.219287 |
geographic |
Arctic Svalbard |
geographic_facet |
Arctic Svalbard |
genre |
Arctic Svalbard |
genre_facet |
Arctic Svalbard |
op_source |
Journal of Experimental Biology; 223(8), no jeb219287 (2020) ISSN: 1477-9145 |
op_relation |
https://lup.lub.lu.se/record/17e57296-9ef7-49c9-a268-0052bf2037e8 http://dx.doi.org/10.1242/jeb.219287 pmid:32341183 scopus:85085255627 |
op_doi |
https://doi.org/10.1242/jeb.219287 |
container_title |
Journal of Experimental Biology |
container_volume |
223 |
container_issue |
8 |
_version_ |
1766325164523388928 |