Characterisation of North American Brucella isolates from marine mammals
Extension of known ecological niches of Brucella has included the description of two novel species from marine mammals. Brucella pinnipedialis is associated predominantly with seals, while two major Brucella ceti clades, most commonly associated with porpoises or dolphins respectively, have been ide...
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ftuglasgow:oai:eprints.gla.ac.uk:274569 2023-05-15T15:41:53+02:00 Characterisation of North American Brucella isolates from marine mammals Whatmore, Adrian M. Dawson, Claire Muchowski, Jakub Perrett, Lorraine L. Stubberfield, Emma Koylass, Mark Foster, Geoffrey Davison, Nicholas J. Quance, Christine Sidor, Inga F. Field, Cara L. St. Leger, Judy 2017-09-21 text https://eprints.gla.ac.uk/274569/ https://eprints.gla.ac.uk/274569/1/274569.pdf en eng Public Library of Science https://eprints.gla.ac.uk/274569/1/274569.pdf Whatmore, A. M. et al. (2017) Characterisation of North American Brucella isolates from marine mammals. PLoS ONE <https://eprints.gla.ac.uk/view/journal_volume/PLoS_ONE.html>, 12(9), e0184758. (doi:10.1371/journal.pone.0184758 <https://doi.org/10.1371/journal.pone.0184758>) (PMID:28934239) (PMCID:PMC5608248) cc_public_domain PDM Articles PeerReviewed 2017 ftuglasgow https://doi.org/10.1371/journal.pone.0184758 2022-09-22T22:17:49Z Extension of known ecological niches of Brucella has included the description of two novel species from marine mammals. Brucella pinnipedialis is associated predominantly with seals, while two major Brucella ceti clades, most commonly associated with porpoises or dolphins respectively, have been identified. To date there has been limited characterisation of Brucella isolates obtained from marine mammals outside Northern European waters, including North American waters. To address this gap, and extend knowledge of the global population structure and host associations of these Brucella species, 61 isolates from marine mammals inhabiting North American waters were subject to molecular and phenotypic characterisation enabling comparison with existing European isolates. The majority of isolates represent genotypes previously described in Europe although novel genotypes were identified in both B. ceti clades. Harp seals were found to carry B. pinnipedialis genotypes previously confined to hooded seals among a diverse repertoire of sequence types (STs) associated with this species. For the first time Brucella isolates were characterised from beluga whales and found to represent a number of distinct B. pinnipedialis genotypes. In addition the known host range of ST27 was extended with the identification of this ST from California sea lion samples. Finally the performance of the frequently used diagnostic tool Bruce-ladder, in differentiating B. ceti and B. pinnipedialis, was critically assessed based on improved knowledge of the global population structure of Brucella associated with marine mammals. Article in Journal/Newspaper Beluga Beluga* University of Glasgow: Enlighten - Publications PLOS ONE 12 9 e0184758 |
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Open Polar |
collection |
University of Glasgow: Enlighten - Publications |
op_collection_id |
ftuglasgow |
language |
English |
description |
Extension of known ecological niches of Brucella has included the description of two novel species from marine mammals. Brucella pinnipedialis is associated predominantly with seals, while two major Brucella ceti clades, most commonly associated with porpoises or dolphins respectively, have been identified. To date there has been limited characterisation of Brucella isolates obtained from marine mammals outside Northern European waters, including North American waters. To address this gap, and extend knowledge of the global population structure and host associations of these Brucella species, 61 isolates from marine mammals inhabiting North American waters were subject to molecular and phenotypic characterisation enabling comparison with existing European isolates. The majority of isolates represent genotypes previously described in Europe although novel genotypes were identified in both B. ceti clades. Harp seals were found to carry B. pinnipedialis genotypes previously confined to hooded seals among a diverse repertoire of sequence types (STs) associated with this species. For the first time Brucella isolates were characterised from beluga whales and found to represent a number of distinct B. pinnipedialis genotypes. In addition the known host range of ST27 was extended with the identification of this ST from California sea lion samples. Finally the performance of the frequently used diagnostic tool Bruce-ladder, in differentiating B. ceti and B. pinnipedialis, was critically assessed based on improved knowledge of the global population structure of Brucella associated with marine mammals. |
format |
Article in Journal/Newspaper |
author |
Whatmore, Adrian M. Dawson, Claire Muchowski, Jakub Perrett, Lorraine L. Stubberfield, Emma Koylass, Mark Foster, Geoffrey Davison, Nicholas J. Quance, Christine Sidor, Inga F. Field, Cara L. St. Leger, Judy |
spellingShingle |
Whatmore, Adrian M. Dawson, Claire Muchowski, Jakub Perrett, Lorraine L. Stubberfield, Emma Koylass, Mark Foster, Geoffrey Davison, Nicholas J. Quance, Christine Sidor, Inga F. Field, Cara L. St. Leger, Judy Characterisation of North American Brucella isolates from marine mammals |
author_facet |
Whatmore, Adrian M. Dawson, Claire Muchowski, Jakub Perrett, Lorraine L. Stubberfield, Emma Koylass, Mark Foster, Geoffrey Davison, Nicholas J. Quance, Christine Sidor, Inga F. Field, Cara L. St. Leger, Judy |
author_sort |
Whatmore, Adrian M. |
title |
Characterisation of North American Brucella isolates from marine mammals |
title_short |
Characterisation of North American Brucella isolates from marine mammals |
title_full |
Characterisation of North American Brucella isolates from marine mammals |
title_fullStr |
Characterisation of North American Brucella isolates from marine mammals |
title_full_unstemmed |
Characterisation of North American Brucella isolates from marine mammals |
title_sort |
characterisation of north american brucella isolates from marine mammals |
publisher |
Public Library of Science |
publishDate |
2017 |
url |
https://eprints.gla.ac.uk/274569/ https://eprints.gla.ac.uk/274569/1/274569.pdf |
genre |
Beluga Beluga* |
genre_facet |
Beluga Beluga* |
op_relation |
https://eprints.gla.ac.uk/274569/1/274569.pdf Whatmore, A. M. et al. (2017) Characterisation of North American Brucella isolates from marine mammals. PLoS ONE <https://eprints.gla.ac.uk/view/journal_volume/PLoS_ONE.html>, 12(9), e0184758. (doi:10.1371/journal.pone.0184758 <https://doi.org/10.1371/journal.pone.0184758>) (PMID:28934239) (PMCID:PMC5608248) |
op_rights |
cc_public_domain |
op_rightsnorm |
PDM |
op_doi |
https://doi.org/10.1371/journal.pone.0184758 |
container_title |
PLOS ONE |
container_volume |
12 |
container_issue |
9 |
container_start_page |
e0184758 |
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1766374763871076352 |