The prevalence of age-related maculopathy in iceland: Reykjavik eye study
OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence...
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ftucl:oai:eprints.ucl.ac.uk.OAI2:189567 2023-05-15T16:47:43+02:00 The prevalence of age-related maculopathy in iceland: Reykjavik eye study Jonasson, F Arnarsson, A Sasaki, H Peto, T Sasaki, K Bird, AC 2003-03 http://discovery.ucl.ac.uk/189567/ unknown Archives of Ophthalmology , 121 (3) 379 - 385. (2003) age Age Distribution Aged 80 and over ARM atrophy characteristics classification clinical Clinical trial CLINICAL-TRIAL COMMON confidence CONTROLLED TRIAL Cross-Sectional Studies design diagnosis difference DISTINCT epidemiology Eye Female Fundus Oculi Iceland IM LA M Macular Degeneration Male Materials Methods Micro Middle Aged OLDER Other PEOPLE Photography Prevalence random sample randomized RANDOMIZED CONTROLLED TRIAL response Result SAMPLE SEVERITY Sex Distribution Support Non-U.S.Gov't SYSTEM TRIAL Article 2003 ftucl 2013-11-10T03:27:48Z OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence and severity of various characteristics of drusen and pigmentary changes that are typical of ARM and AMD were determined by grading stereoscopic color fundus photographs, using the international classification and grading system for ARM and AMD. RESULTS: We were able to evaluate 1021 right-eye and 1020 left-eye macular photographs. There was no statistically significant difference between right and left eyes. In people aged 50 to 59 years, 4.8% of participants (95% confidence interval [CI], 2.6-7.0) were found to have intermediate soft drusen measuring 63 to 125 micro m in either eye; 1.2% (95% CI, 0.0-2.3) had large soft distinct drusen larger than 125 micro m; and 0.6% (95% CI, 0.0-1.4) had large soft, crystalline, or semisolid drusen. The same figures for those 80 years and older were 18.2% (95% CI, 9.8-26.6), 10.9% (95% CI, 4.0-17.8), and 25.5% (95% CI, 18.4-32.6), respectively. Geographic atrophy was found in either eye in 9.2% of those participants 70 years and older (95% CI, 5.6-12.7), and exudative macular degeneration was found in 2.3% of participants 70 years and older (95% CI, 0.5-4.1). CONCLUSION: Geographic atrophy was found to be more common in our study than in other population-based studies Article in Journal/Newspaper Iceland University College London: UCL Discovery |
institution |
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University College London: UCL Discovery |
op_collection_id |
ftucl |
language |
unknown |
topic |
age Age Distribution Aged 80 and over ARM atrophy characteristics classification clinical Clinical trial CLINICAL-TRIAL COMMON confidence CONTROLLED TRIAL Cross-Sectional Studies design diagnosis difference DISTINCT epidemiology Eye Female Fundus Oculi Iceland IM LA M Macular Degeneration Male Materials Methods Micro Middle Aged OLDER Other PEOPLE Photography Prevalence random sample randomized RANDOMIZED CONTROLLED TRIAL response Result SAMPLE SEVERITY Sex Distribution Support Non-U.S.Gov't SYSTEM TRIAL |
spellingShingle |
age Age Distribution Aged 80 and over ARM atrophy characteristics classification clinical Clinical trial CLINICAL-TRIAL COMMON confidence CONTROLLED TRIAL Cross-Sectional Studies design diagnosis difference DISTINCT epidemiology Eye Female Fundus Oculi Iceland IM LA M Macular Degeneration Male Materials Methods Micro Middle Aged OLDER Other PEOPLE Photography Prevalence random sample randomized RANDOMIZED CONTROLLED TRIAL response Result SAMPLE SEVERITY Sex Distribution Support Non-U.S.Gov't SYSTEM TRIAL Jonasson, F Arnarsson, A Sasaki, H Peto, T Sasaki, K Bird, AC The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
topic_facet |
age Age Distribution Aged 80 and over ARM atrophy characteristics classification clinical Clinical trial CLINICAL-TRIAL COMMON confidence CONTROLLED TRIAL Cross-Sectional Studies design diagnosis difference DISTINCT epidemiology Eye Female Fundus Oculi Iceland IM LA M Macular Degeneration Male Materials Methods Micro Middle Aged OLDER Other PEOPLE Photography Prevalence random sample randomized RANDOMIZED CONTROLLED TRIAL response Result SAMPLE SEVERITY Sex Distribution Support Non-U.S.Gov't SYSTEM TRIAL |
description |
OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence and severity of various characteristics of drusen and pigmentary changes that are typical of ARM and AMD were determined by grading stereoscopic color fundus photographs, using the international classification and grading system for ARM and AMD. RESULTS: We were able to evaluate 1021 right-eye and 1020 left-eye macular photographs. There was no statistically significant difference between right and left eyes. In people aged 50 to 59 years, 4.8% of participants (95% confidence interval [CI], 2.6-7.0) were found to have intermediate soft drusen measuring 63 to 125 micro m in either eye; 1.2% (95% CI, 0.0-2.3) had large soft distinct drusen larger than 125 micro m; and 0.6% (95% CI, 0.0-1.4) had large soft, crystalline, or semisolid drusen. The same figures for those 80 years and older were 18.2% (95% CI, 9.8-26.6), 10.9% (95% CI, 4.0-17.8), and 25.5% (95% CI, 18.4-32.6), respectively. Geographic atrophy was found in either eye in 9.2% of those participants 70 years and older (95% CI, 5.6-12.7), and exudative macular degeneration was found in 2.3% of participants 70 years and older (95% CI, 0.5-4.1). CONCLUSION: Geographic atrophy was found to be more common in our study than in other population-based studies |
format |
Article in Journal/Newspaper |
author |
Jonasson, F Arnarsson, A Sasaki, H Peto, T Sasaki, K Bird, AC |
author_facet |
Jonasson, F Arnarsson, A Sasaki, H Peto, T Sasaki, K Bird, AC |
author_sort |
Jonasson, F |
title |
The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
title_short |
The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
title_full |
The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
title_fullStr |
The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
title_full_unstemmed |
The prevalence of age-related maculopathy in iceland: Reykjavik eye study |
title_sort |
prevalence of age-related maculopathy in iceland: reykjavik eye study |
publishDate |
2003 |
url |
http://discovery.ucl.ac.uk/189567/ |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Archives of Ophthalmology , 121 (3) 379 - 385. (2003) |
_version_ |
1766037797080137728 |