Association between duration of untreated psychosis and brain morphology in schizophrenia within the Northern Finland 1966 Birth Cohort.

Duration of untreated psychosis (DUP) has been linked with poor prognosis and changes in the brain structure in schizophrenia at least at the beginning of the disease, but it is still unknown whether DUP relates to brain morphometry in the longer term. Our aim was to analyze the relation between DUP...

Full description

Bibliographic Details
Main Authors: Penttilä, M, Jääskeläinen, E, Haapea, M, Tanskanen, P, Veijola, J, Ridler, K, Murray, GK, Barnes, A, Jones, PB, Isohanni, M, Koponen, H, Miettunen, J
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Adult
Brain
Diagnostic and Statistical Manual of Mental Disorders
Female
Finland
Follow-Up Studies
Functional Laterality
Hippocampus
Humans
Limbic System
Magnetic Resonance Imaging
Male
Medical Records Systems
Computerized
Psychotic Disorders
Regression Analysis
Schizophrenia
Schizophrenic Psychology
Time Factors
Northern Finland
Online Access:http://discovery.ucl.ac.uk/1420419/
Description
Summary:Duration of untreated psychosis (DUP) has been linked with poor prognosis and changes in the brain structure in schizophrenia at least at the beginning of the disease, but it is still unknown whether DUP relates to brain morphometry in the longer term. Our aim was to analyze the relation between DUP and the brain structure in schizophrenia in the general population, after several years of illness.

Similar Items