Measurement of carbonyl chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy: comparison between uniformly and selectively (13)C labeled samples.

• Main Authors: Lundström, P, Hansen, DF, Kay, LE
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2008
• Subjects: Carbon Isotopes; Carbonic Acid; Molecular Structure; Nuclear Magnetic Resonance; Biomolecular; Proteins; Carr; Carbonic acid
• Online Access: http://discovery.ucl.ac.uk/1308598/

Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion nuclear magnetic resonance (NMR) spectroscopy has emerged as a powerful method for quantifying chemical shifts of excited protein states. For many applications of the technique that involve the measurement of relaxation rates of carbon magnetiza...