Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ec...
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ftubarcepubl:oai:diposit.ub.edu:2445/193221 2024-02-11T09:57:45+01:00 Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential Martín Martín, Rafael Pablo Carcedo-Forés, Marta Camacho-Bolós, Pablo García Aljaro, Cristina Angulo Preckler, Carlos Ávila Escartín, Conxita Rull, Jordi Gómez Garreta, Ma. Amelia 2022-04-25 application/pdf http://hdl.handle.net/2445/193221 eng eng Springer Verlag Reproducció del document publicat a: https://doi.org/10.1007/s00300-022-03036-1 Polar Biology, 2022 Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) https://doi.org/10.1007/s00300-022-03036-1 0722-4060 http://hdl.handle.net/2445/193221 723111 cc by (c) Rafael Pablo Martín Martín, et al., 2022 http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Algues marines Antibiòtics Antàrtic Oceà Marine algae Antibiotics Antarctic Ocean info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2022 ftubarcepubl https://doi.org/10.1007/s00300-022-03036-1 2024-01-24T01:19:21Z Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ecology of seaweeds is not equally understood across different regions; for example, Antarctic seaweeds are among the lesser studied groups. With the aim of improving our current understanding of the chemical ecology and potential bioactivity of Antarctic seaweeds, we performed a screening of antibiotic activity using crude extracts from 22 Antarctic macroalgae species. Extractions were performed separating lipophilic and hydrophilic fractions at natural concentrations. Antimicrobial activity assays were performed using the disk diffusion method against seven Antarctic bacteria and seven human pathogenic surrogates. Our results showed that red seaweeds (especially Delisea pulchra) inhibited a larger number of microorganisms compared with brown seaweeds, and that lipophilic fractions were more active than hydrophilic ones. Both types of bacteria tested (Gram negative and Gram positive) were inhibited, especially by butanolic fractions, suggesting a trend of non-specific chemical defence. However, Gram-negative bacteria and one pathogenic fungus showed greater resistance. Our study contributes to the evidence of antimicrobial chemical interactions between Antarctic seaweeds and sympatric microorganisms, as well as the potential of seaweed extracts for pharmacological applications. Article in Journal/Newspaper Antarc* Antarctic Antarctic Ocean Polar Biology Dipòsit Digital de la Universitat de Barcelona Antarctic Antarctic Ocean Polar Biology 45 5 923 936 |
institution |
Open Polar |
collection |
Dipòsit Digital de la Universitat de Barcelona |
op_collection_id |
ftubarcepubl |
language |
English |
topic |
Algues marines Antibiòtics Antàrtic Oceà Marine algae Antibiotics Antarctic Ocean |
spellingShingle |
Algues marines Antibiòtics Antàrtic Oceà Marine algae Antibiotics Antarctic Ocean Martín Martín, Rafael Pablo Carcedo-Forés, Marta Camacho-Bolós, Pablo García Aljaro, Cristina Angulo Preckler, Carlos Ávila Escartín, Conxita Rull, Jordi Gómez Garreta, Ma. Amelia Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
topic_facet |
Algues marines Antibiòtics Antàrtic Oceà Marine algae Antibiotics Antarctic Ocean |
description |
Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ecology of seaweeds is not equally understood across different regions; for example, Antarctic seaweeds are among the lesser studied groups. With the aim of improving our current understanding of the chemical ecology and potential bioactivity of Antarctic seaweeds, we performed a screening of antibiotic activity using crude extracts from 22 Antarctic macroalgae species. Extractions were performed separating lipophilic and hydrophilic fractions at natural concentrations. Antimicrobial activity assays were performed using the disk diffusion method against seven Antarctic bacteria and seven human pathogenic surrogates. Our results showed that red seaweeds (especially Delisea pulchra) inhibited a larger number of microorganisms compared with brown seaweeds, and that lipophilic fractions were more active than hydrophilic ones. Both types of bacteria tested (Gram negative and Gram positive) were inhibited, especially by butanolic fractions, suggesting a trend of non-specific chemical defence. However, Gram-negative bacteria and one pathogenic fungus showed greater resistance. Our study contributes to the evidence of antimicrobial chemical interactions between Antarctic seaweeds and sympatric microorganisms, as well as the potential of seaweed extracts for pharmacological applications. |
format |
Article in Journal/Newspaper |
author |
Martín Martín, Rafael Pablo Carcedo-Forés, Marta Camacho-Bolós, Pablo García Aljaro, Cristina Angulo Preckler, Carlos Ávila Escartín, Conxita Rull, Jordi Gómez Garreta, Ma. Amelia |
author_facet |
Martín Martín, Rafael Pablo Carcedo-Forés, Marta Camacho-Bolós, Pablo García Aljaro, Cristina Angulo Preckler, Carlos Ávila Escartín, Conxita Rull, Jordi Gómez Garreta, Ma. Amelia |
author_sort |
Martín Martín, Rafael Pablo |
title |
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
title_short |
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
title_full |
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
title_fullStr |
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
title_full_unstemmed |
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential |
title_sort |
experimental evidence of antimicrobial activity in antarctic seaweeds: ecological role and antibiotic potential |
publisher |
Springer Verlag |
publishDate |
2022 |
url |
http://hdl.handle.net/2445/193221 |
geographic |
Antarctic Antarctic Ocean |
geographic_facet |
Antarctic Antarctic Ocean |
genre |
Antarc* Antarctic Antarctic Ocean Polar Biology |
genre_facet |
Antarc* Antarctic Antarctic Ocean Polar Biology |
op_relation |
Reproducció del document publicat a: https://doi.org/10.1007/s00300-022-03036-1 Polar Biology, 2022 Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) https://doi.org/10.1007/s00300-022-03036-1 0722-4060 http://hdl.handle.net/2445/193221 723111 |
op_rights |
cc by (c) Rafael Pablo Martín Martín, et al., 2022 http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1007/s00300-022-03036-1 |
container_title |
Polar Biology |
container_volume |
45 |
container_issue |
5 |
container_start_page |
923 |
op_container_end_page |
936 |
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1790593307907194880 |