Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential

Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ec...

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Published in:Polar Biology
Main Authors: Martín Martín, Rafael Pablo, Carcedo-Forés, Marta, Camacho-Bolós, Pablo, García Aljaro, Cristina, Angulo Preckler, Carlos, Ávila Escartín, Conxita, Rull, Jordi, Gómez Garreta, Ma. Amelia
Format: Article in Journal/Newspaper
Language:English
Published: Springer Verlag 2022
Subjects:
Online Access:http://hdl.handle.net/2445/193221
id ftubarcepubl:oai:diposit.ub.edu:2445/193221
record_format openpolar
spelling ftubarcepubl:oai:diposit.ub.edu:2445/193221 2024-02-11T09:57:45+01:00 Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential Martín Martín, Rafael Pablo Carcedo-Forés, Marta Camacho-Bolós, Pablo García Aljaro, Cristina Angulo Preckler, Carlos Ávila Escartín, Conxita Rull, Jordi Gómez Garreta, Ma. Amelia 2022-04-25 application/pdf http://hdl.handle.net/2445/193221 eng eng Springer Verlag Reproducció del document publicat a: https://doi.org/10.1007/s00300-022-03036-1 Polar Biology, 2022 Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) https://doi.org/10.1007/s00300-022-03036-1 0722-4060 http://hdl.handle.net/2445/193221 723111 cc by (c) Rafael Pablo Martín Martín, et al., 2022 http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Algues marines Antibiòtics Antàrtic Oceà Marine algae Antibiotics Antarctic Ocean info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2022 ftubarcepubl https://doi.org/10.1007/s00300-022-03036-1 2024-01-24T01:19:21Z Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ecology of seaweeds is not equally understood across different regions; for example, Antarctic seaweeds are among the lesser studied groups. With the aim of improving our current understanding of the chemical ecology and potential bioactivity of Antarctic seaweeds, we performed a screening of antibiotic activity using crude extracts from 22 Antarctic macroalgae species. Extractions were performed separating lipophilic and hydrophilic fractions at natural concentrations. Antimicrobial activity assays were performed using the disk diffusion method against seven Antarctic bacteria and seven human pathogenic surrogates. Our results showed that red seaweeds (especially Delisea pulchra) inhibited a larger number of microorganisms compared with brown seaweeds, and that lipophilic fractions were more active than hydrophilic ones. Both types of bacteria tested (Gram negative and Gram positive) were inhibited, especially by butanolic fractions, suggesting a trend of non-specific chemical defence. However, Gram-negative bacteria and one pathogenic fungus showed greater resistance. Our study contributes to the evidence of antimicrobial chemical interactions between Antarctic seaweeds and sympatric microorganisms, as well as the potential of seaweed extracts for pharmacological applications. Article in Journal/Newspaper Antarc* Antarctic Antarctic Ocean Polar Biology Dipòsit Digital de la Universitat de Barcelona Antarctic Antarctic Ocean Polar Biology 45 5 923 936
institution Open Polar
collection Dipòsit Digital de la Universitat de Barcelona
op_collection_id ftubarcepubl
language English
topic Algues marines
Antibiòtics
Antàrtic
Oceà
Marine algae
Antibiotics
Antarctic Ocean
spellingShingle Algues marines
Antibiòtics
Antàrtic
Oceà
Marine algae
Antibiotics
Antarctic Ocean
Martín Martín, Rafael Pablo
Carcedo-Forés, Marta
Camacho-Bolós, Pablo
García Aljaro, Cristina
Angulo Preckler, Carlos
Ávila Escartín, Conxita
Rull, Jordi
Gómez Garreta, Ma. Amelia
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
topic_facet Algues marines
Antibiòtics
Antàrtic
Oceà
Marine algae
Antibiotics
Antarctic Ocean
description Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ecology of seaweeds is not equally understood across different regions; for example, Antarctic seaweeds are among the lesser studied groups. With the aim of improving our current understanding of the chemical ecology and potential bioactivity of Antarctic seaweeds, we performed a screening of antibiotic activity using crude extracts from 22 Antarctic macroalgae species. Extractions were performed separating lipophilic and hydrophilic fractions at natural concentrations. Antimicrobial activity assays were performed using the disk diffusion method against seven Antarctic bacteria and seven human pathogenic surrogates. Our results showed that red seaweeds (especially Delisea pulchra) inhibited a larger number of microorganisms compared with brown seaweeds, and that lipophilic fractions were more active than hydrophilic ones. Both types of bacteria tested (Gram negative and Gram positive) were inhibited, especially by butanolic fractions, suggesting a trend of non-specific chemical defence. However, Gram-negative bacteria and one pathogenic fungus showed greater resistance. Our study contributes to the evidence of antimicrobial chemical interactions between Antarctic seaweeds and sympatric microorganisms, as well as the potential of seaweed extracts for pharmacological applications.
format Article in Journal/Newspaper
author Martín Martín, Rafael Pablo
Carcedo-Forés, Marta
Camacho-Bolós, Pablo
García Aljaro, Cristina
Angulo Preckler, Carlos
Ávila Escartín, Conxita
Rull, Jordi
Gómez Garreta, Ma. Amelia
author_facet Martín Martín, Rafael Pablo
Carcedo-Forés, Marta
Camacho-Bolós, Pablo
García Aljaro, Cristina
Angulo Preckler, Carlos
Ávila Escartín, Conxita
Rull, Jordi
Gómez Garreta, Ma. Amelia
author_sort Martín Martín, Rafael Pablo
title Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
title_short Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
title_full Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
title_fullStr Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
title_full_unstemmed Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
title_sort experimental evidence of antimicrobial activity in antarctic seaweeds: ecological role and antibiotic potential
publisher Springer Verlag
publishDate 2022
url http://hdl.handle.net/2445/193221
geographic Antarctic
Antarctic Ocean
geographic_facet Antarctic
Antarctic Ocean
genre Antarc*
Antarctic
Antarctic Ocean
Polar Biology
genre_facet Antarc*
Antarctic
Antarctic Ocean
Polar Biology
op_relation Reproducció del document publicat a: https://doi.org/10.1007/s00300-022-03036-1
Polar Biology, 2022
Articles publicats en revistes (Biologia, Sanitat i Medi Ambient)
https://doi.org/10.1007/s00300-022-03036-1
0722-4060
http://hdl.handle.net/2445/193221
723111
op_rights cc by (c) Rafael Pablo Martín Martín, et al., 2022
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.1007/s00300-022-03036-1
container_title Polar Biology
container_volume 45
container_issue 5
container_start_page 923
op_container_end_page 936
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