Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments
Cyanotoxins are secondary metabolites produced by cyanobacteria, of varied chemical nature and toxic effects. Although cyanobacteria thrive in all kinds of ecosystems on Earth even under very harsh conditions, current knowledge on cyanotoxin distribution is almost restricted to freshwaters from temp...
Published in: | Marine Drugs |
---|---|
Main Authors: | , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI
2024
|
Subjects: | |
Online Access: | http://hdl.handle.net/10486/713254 https://doi.org/10.3390/md15070233 |
id |
ftuamadrid:oai:repositorio.uam.es:10486/713254 |
---|---|
record_format |
openpolar |
spelling |
ftuamadrid:oai:repositorio.uam.es:10486/713254 2024-06-23T07:47:08+00:00 Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments Cires Gómez, Samuel Casero, María Cristina Quesada del Corral, Antonio UAM. Departamento de Biología 2024-06-11T15:52:25Z application/pdf http://hdl.handle.net/10486/713254 https://doi.org/10.3390/md15070233 eng eng MDPI Marine drugs https://doi.org/10.3390/md15070233 Marine Drugs. 15.7 (2017): 1-18 1660-3397 http://hdl.handle.net/10486/713254 doi:10.3390/md15070233 1 18 © 2017 by the authors http://creativecommons.org/licenses/by/4.0/ Reconocimiento openAccess anatoxin-a cylindrospermopsin microcystin nodularin extremophiles Arctic Antarctica hot deserts hypersaline alkaline lakes Biología y Biomedicina / Biología article info:eu-repo/semantics/acceptedVersion 2024 ftuamadrid https://doi.org/10.3390/md15070233 2024-06-11T23:50:31Z Cyanotoxins are secondary metabolites produced by cyanobacteria, of varied chemical nature and toxic effects. Although cyanobacteria thrive in all kinds of ecosystems on Earth even under very harsh conditions, current knowledge on cyanotoxin distribution is almost restricted to freshwaters from temperate latitudes. In this review, we bring to the forefront the presence of cyanotoxins in extreme environments. Cyanotoxins have been reported especially in polar deserts (both from the Arctic and Antarctica) and alkaline lakes, but also in hot deserts, hypersaline environments, and hot springs. Cyanotoxins detected in these ecosystems include neurotoxins—anatoxin-a, anatoxin-a (S), paralytic shellfish toxins, -methylaminopropionic acid, N-(2-aminoethyl) glycine and 2,4-diaminobutyric acid- and hepatotoxins –cylindrospermopsins, microcystins and nodularins—with microcystins being the most frequently reported. Toxin production there has been linked to at least eleven cyanobacterial genera yet only three of these (Arthrospira, Synechococcus and Oscillatoria) have been confirmed as producers in culture. Beyond a comprehensive analysis of cyanotoxin presence in each of the extreme environments, this review also identifies the main knowledge gaps to overcome (e.g., scarcity of isolates and –omics data, among others) toward an initial assessment of ecological and human health risks in these amazing ecosystems developing at the very edge of life María Cristina Casero was funded by the Spanish PhD research fellowship (BES-2014-069106) awarded by the Spanish Ministry of Economy and Competitiveness. We would like to thank the two anonymous reviewers for offering constructive comments on an earlier version of this manuscript. Article in Journal/Newspaper Antarc* Antarctica Arctic Human health Universidad Autónoma de Madrid (UAM): Biblos-e Archivo Arctic Marine Drugs 15 7 233 |
institution |
Open Polar |
collection |
Universidad Autónoma de Madrid (UAM): Biblos-e Archivo |
op_collection_id |
ftuamadrid |
language |
English |
topic |
anatoxin-a cylindrospermopsin microcystin nodularin extremophiles Arctic Antarctica hot deserts hypersaline alkaline lakes Biología y Biomedicina / Biología |
spellingShingle |
anatoxin-a cylindrospermopsin microcystin nodularin extremophiles Arctic Antarctica hot deserts hypersaline alkaline lakes Biología y Biomedicina / Biología Cires Gómez, Samuel Casero, María Cristina Quesada del Corral, Antonio Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
topic_facet |
anatoxin-a cylindrospermopsin microcystin nodularin extremophiles Arctic Antarctica hot deserts hypersaline alkaline lakes Biología y Biomedicina / Biología |
description |
Cyanotoxins are secondary metabolites produced by cyanobacteria, of varied chemical nature and toxic effects. Although cyanobacteria thrive in all kinds of ecosystems on Earth even under very harsh conditions, current knowledge on cyanotoxin distribution is almost restricted to freshwaters from temperate latitudes. In this review, we bring to the forefront the presence of cyanotoxins in extreme environments. Cyanotoxins have been reported especially in polar deserts (both from the Arctic and Antarctica) and alkaline lakes, but also in hot deserts, hypersaline environments, and hot springs. Cyanotoxins detected in these ecosystems include neurotoxins—anatoxin-a, anatoxin-a (S), paralytic shellfish toxins, -methylaminopropionic acid, N-(2-aminoethyl) glycine and 2,4-diaminobutyric acid- and hepatotoxins –cylindrospermopsins, microcystins and nodularins—with microcystins being the most frequently reported. Toxin production there has been linked to at least eleven cyanobacterial genera yet only three of these (Arthrospira, Synechococcus and Oscillatoria) have been confirmed as producers in culture. Beyond a comprehensive analysis of cyanotoxin presence in each of the extreme environments, this review also identifies the main knowledge gaps to overcome (e.g., scarcity of isolates and –omics data, among others) toward an initial assessment of ecological and human health risks in these amazing ecosystems developing at the very edge of life María Cristina Casero was funded by the Spanish PhD research fellowship (BES-2014-069106) awarded by the Spanish Ministry of Economy and Competitiveness. We would like to thank the two anonymous reviewers for offering constructive comments on an earlier version of this manuscript. |
author2 |
UAM. Departamento de Biología |
format |
Article in Journal/Newspaper |
author |
Cires Gómez, Samuel Casero, María Cristina Quesada del Corral, Antonio |
author_facet |
Cires Gómez, Samuel Casero, María Cristina Quesada del Corral, Antonio |
author_sort |
Cires Gómez, Samuel |
title |
Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
title_short |
Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
title_full |
Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
title_fullStr |
Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
title_full_unstemmed |
Toxicity at the edge of life: A review on cyanobacterial toxins from extreme environments |
title_sort |
toxicity at the edge of life: a review on cyanobacterial toxins from extreme environments |
publisher |
MDPI |
publishDate |
2024 |
url |
http://hdl.handle.net/10486/713254 https://doi.org/10.3390/md15070233 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Antarc* Antarctica Arctic Human health |
genre_facet |
Antarc* Antarctica Arctic Human health |
op_relation |
Marine drugs https://doi.org/10.3390/md15070233 Marine Drugs. 15.7 (2017): 1-18 1660-3397 http://hdl.handle.net/10486/713254 doi:10.3390/md15070233 1 18 |
op_rights |
© 2017 by the authors http://creativecommons.org/licenses/by/4.0/ Reconocimiento openAccess |
op_doi |
https://doi.org/10.3390/md15070233 |
container_title |
Marine Drugs |
container_volume |
15 |
container_issue |
7 |
container_start_page |
233 |
_version_ |
1802651233827160064 |