Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements
Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution,...
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ftuabarcelonapb:oai:ddd.uab.cat:272327 2023-05-15T14:05:12+02:00 Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements Santos, Andrés Burgos, Felipe Martinez-Urtaza, Jaime Barrientos, Leticia 2022 application/pdf https://ddd.uab.cat/record/272327 eng eng Microorganisms Vol. 10, Issue 7 (July 2022), art. 1432 https://ddd.uab.cat/record/272327 urn:10.3390/microorganisms10071432 urn:oai:ddd.uab.cat:272327 urn:oai:egreta.uab.cat:publications/bc5f89f7-bf83-4bbd-b38c-e75491a721bd urn:pure_id:241453092 urn:scopus_id:85137214949 urn:pmid:35889151 urn:pmcid:PMC9320737 urn:articleid:20762607v10n7p1432 urn:pmc-uid:9320737 urn:oai:pubmedcentral.nih.gov:9320737 open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ CC-BY Antarctic soils Phages Plasmids Pristine environments Suelos antárticos Fagos Plásmidos Ambientes prístinos Article 2022 ftuabarcelonapb 2023-03-08T00:53:59Z Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs and the importance of mobile genetic elements as a possible mechanism for the dissemination of resistance genes in Antarctica. We analyzed five soil metagenomes from Deception Island in Antarctica. Results showed that detected ARGs are associated with mechanisms such as antibiotic efflux, antibiotic inactivation, and target alteration. On the other hand, resistance to metals, surfactants, and aromatic hydrocarbons were the dominant ERGs. The taxonomy of ARGs showed that Pseudomonas, Psychrobacter, and Staphylococcus could be key taxa for studying antibiotic resistance and environmental resistance to stress in Deception Island. In addition, results showed that ARGs are mainly associated with phage-type mobile elements suggesting a potential role in their dissemination and prevalence. Finally, these results provide valuable information regarding the ARGs and ERGs in Deception Island including the potential contribution of mobile genetic elements to the spread of ARGs and ERGs in one of the least studied Antarctic ecosystems to date. Article in Journal/Newspaper Antarc* Antarctic Antarctica Deception Island Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB Antarctic Deception Island ENVELOPE(-60.633,-60.633,-62.950,-62.950) |
institution |
Open Polar |
collection |
Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB |
op_collection_id |
ftuabarcelonapb |
language |
English |
topic |
Antarctic soils Phages Plasmids Pristine environments Suelos antárticos Fagos Plásmidos Ambientes prístinos |
spellingShingle |
Antarctic soils Phages Plasmids Pristine environments Suelos antárticos Fagos Plásmidos Ambientes prístinos Santos, Andrés Burgos, Felipe Martinez-Urtaza, Jaime Barrientos, Leticia Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
topic_facet |
Antarctic soils Phages Plasmids Pristine environments Suelos antárticos Fagos Plásmidos Ambientes prístinos |
description |
Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs and the importance of mobile genetic elements as a possible mechanism for the dissemination of resistance genes in Antarctica. We analyzed five soil metagenomes from Deception Island in Antarctica. Results showed that detected ARGs are associated with mechanisms such as antibiotic efflux, antibiotic inactivation, and target alteration. On the other hand, resistance to metals, surfactants, and aromatic hydrocarbons were the dominant ERGs. The taxonomy of ARGs showed that Pseudomonas, Psychrobacter, and Staphylococcus could be key taxa for studying antibiotic resistance and environmental resistance to stress in Deception Island. In addition, results showed that ARGs are mainly associated with phage-type mobile elements suggesting a potential role in their dissemination and prevalence. Finally, these results provide valuable information regarding the ARGs and ERGs in Deception Island including the potential contribution of mobile genetic elements to the spread of ARGs and ERGs in one of the least studied Antarctic ecosystems to date. |
format |
Article in Journal/Newspaper |
author |
Santos, Andrés Burgos, Felipe Martinez-Urtaza, Jaime Barrientos, Leticia |
author_facet |
Santos, Andrés Burgos, Felipe Martinez-Urtaza, Jaime Barrientos, Leticia |
author_sort |
Santos, Andrés |
title |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_short |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_full |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_fullStr |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_full_unstemmed |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_sort |
metagenomic characterization of resistance genes in deception island and their association with mobile genetic elements |
publishDate |
2022 |
url |
https://ddd.uab.cat/record/272327 |
long_lat |
ENVELOPE(-60.633,-60.633,-62.950,-62.950) |
geographic |
Antarctic Deception Island |
geographic_facet |
Antarctic Deception Island |
genre |
Antarc* Antarctic Antarctica Deception Island |
genre_facet |
Antarc* Antarctic Antarctica Deception Island |
op_relation |
Microorganisms Vol. 10, Issue 7 (July 2022), art. 1432 https://ddd.uab.cat/record/272327 urn:10.3390/microorganisms10071432 urn:oai:ddd.uab.cat:272327 urn:oai:egreta.uab.cat:publications/bc5f89f7-bf83-4bbd-b38c-e75491a721bd urn:pure_id:241453092 urn:scopus_id:85137214949 urn:pmid:35889151 urn:pmcid:PMC9320737 urn:articleid:20762607v10n7p1432 urn:pmc-uid:9320737 urn:oai:pubmedcentral.nih.gov:9320737 |
op_rights |
open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
_version_ |
1766276931222765568 |