Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus
Altres ajuts: SNSF/31003A_169211/1 The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological section...
Published in: | International Journal for Parasitology: Parasites and Wildlife |
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ftuabarcelonapb:oai:ddd.uab.cat:227945 2023-05-15T14:30:05+02:00 Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus Padrós, Francesc, Knudsen, R. Blasco-Costa, I. 2018 application/pdf https://ddd.uab.cat/record/227945 eng eng International Journal for Parasitology: Parasites and Wildlife Vol. 7 (january 2018), p. 68-74 https://ddd.uab.cat/record/227945 urn:10.1016/j.ijppaw.2018.01.007 urn:oai:ddd.uab.cat:227945 urn:pmid:29988817 urn:pmcid:PMC6032039 urn:pmc-uid:6032039 urn:articleid:22132244v7p68 urn:oai:egreta.uab.cat:publications/95b56352-eaba-4e52-a431-f8a541b369db urn:scopus_id:85042657100 urn:oai:pubmedcentral.nih.gov:6032039 open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ CC-BY Helminths Eyeflukes Retina Pathology Salmonidae Freshwater Article 2018 ftuabarcelonapb 2023-02-06T21:20:45Z Altres ajuts: SNSF/31003A_169211/1 The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused mechanical disengagement between the retinal pigmentary epithelium and the neurosensory retina, with damaged cones and rods in the outer segment and epithelium reduced to a single layer of pigmentary cells. The metacercariae were "floating" in possibly fluid-filled vesicles together with several round cells, mostly located in the anterio-dorsal and anterio-ventral areas of the eye near the iris. The round cells may indicate internal retinal damage repair mechanisms, without connections to the general immune system. Metacercariae intestines contained pigmented cellular debris indicating that they feed on retinal epithelium. These retinal lesions may have similar vision effects as focal retinal detachment in vertebrates. Diplostomum metacercaria alters fish visual acuity but may in a lesser degree lead to a severe or total visual impairment because of repairing mechanisms. The pathology in the retina seems thereby to be dependent on fish size, age and dose. Article in Journal/Newspaper Arctic charr Arctic Salvelinus alpinus Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB Arctic International Journal for Parasitology: Parasites and Wildlife 7 1 68 74 |
institution |
Open Polar |
collection |
Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB |
op_collection_id |
ftuabarcelonapb |
language |
English |
topic |
Helminths Eyeflukes Retina Pathology Salmonidae Freshwater |
spellingShingle |
Helminths Eyeflukes Retina Pathology Salmonidae Freshwater Padrós, Francesc, Knudsen, R. Blasco-Costa, I. Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
topic_facet |
Helminths Eyeflukes Retina Pathology Salmonidae Freshwater |
description |
Altres ajuts: SNSF/31003A_169211/1 The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused mechanical disengagement between the retinal pigmentary epithelium and the neurosensory retina, with damaged cones and rods in the outer segment and epithelium reduced to a single layer of pigmentary cells. The metacercariae were "floating" in possibly fluid-filled vesicles together with several round cells, mostly located in the anterio-dorsal and anterio-ventral areas of the eye near the iris. The round cells may indicate internal retinal damage repair mechanisms, without connections to the general immune system. Metacercariae intestines contained pigmented cellular debris indicating that they feed on retinal epithelium. These retinal lesions may have similar vision effects as focal retinal detachment in vertebrates. Diplostomum metacercaria alters fish visual acuity but may in a lesser degree lead to a severe or total visual impairment because of repairing mechanisms. The pathology in the retina seems thereby to be dependent on fish size, age and dose. |
format |
Article in Journal/Newspaper |
author |
Padrós, Francesc, Knudsen, R. Blasco-Costa, I. |
author_facet |
Padrós, Francesc, Knudsen, R. Blasco-Costa, I. |
author_sort |
Padrós, Francesc, |
title |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_short |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_full |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_fullStr |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_full_unstemmed |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes : Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_sort |
histopathological characterisation of retinal lesions associated to diplostomum species (platyhelminthes : trematoda) infection in polymorphic arctic charr salvelinus alpinus |
publishDate |
2018 |
url |
https://ddd.uab.cat/record/227945 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic charr Arctic Salvelinus alpinus |
genre_facet |
Arctic charr Arctic Salvelinus alpinus |
op_relation |
International Journal for Parasitology: Parasites and Wildlife Vol. 7 (january 2018), p. 68-74 https://ddd.uab.cat/record/227945 urn:10.1016/j.ijppaw.2018.01.007 urn:oai:ddd.uab.cat:227945 urn:pmid:29988817 urn:pmcid:PMC6032039 urn:pmc-uid:6032039 urn:articleid:22132244v7p68 urn:oai:egreta.uab.cat:publications/95b56352-eaba-4e52-a431-f8a541b369db urn:scopus_id:85042657100 urn:oai:pubmedcentral.nih.gov:6032039 |
op_rights |
open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
container_title |
International Journal for Parasitology: Parasites and Wildlife |
container_volume |
7 |
container_issue |
1 |
container_start_page |
68 |
op_container_end_page |
74 |
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1766303999182503936 |