Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents

Epoxides are important synthetic intermediates for the synthesis of a broad range of industrial products. This study presents a promising solution to the current limitation of enzyme instability. By using simple deep eutectic solvents such as choline chloride/sorbitol, significant stabilization of t...

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Published in:RSC Advances
Main Authors: Zhou, Pengfei (author), Wang, Xuping (author), Yang, Bo (author), Hollmann, F. (author), Wang, Yonghua (author)
Format: Article in Journal/Newspaper
Language:English
Published: 2017
Subjects:
Antarc*
Antarctica
Online Access:http://resolver.tudelft.nl/uuid:a472564f-492d-4094-8de3-fdf53a84d095
https://doi.org/10.1039/c7ra00805h
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spelling fttudelft:oai:tudelft.nl:uuid:a472564f-492d-4094-8de3-fdf53a84d095 2024-02-11T09:57:13+01:00 Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents Zhou, Pengfei (author) Wang, Xuping (author) Yang, Bo (author) Hollmann, F. (author) Wang, Yonghua (author) 2017 http://resolver.tudelft.nl/uuid:a472564f-492d-4094-8de3-fdf53a84d095 https://doi.org/10.1039/c7ra00805h en eng http://resolver.tudelft.nl/uuid:a472564f-492d-4094-8de3-fdf53a84d095 RSC Advances--2046-2069--c5717579-38c9-4252-9db0-b73a9948d660 https://doi.org/10.1039/c7ra00805h © 2017 Pengfei Zhou, Xuping Wang, Bo Yang, F. Hollmann, Yonghua Wang journal article 2017 fttudelft https://doi.org/10.1039/c7ra00805h 2024-01-24T23:29:12Z Epoxides are important synthetic intermediates for the synthesis of a broad range of industrial products. This study presents a promising solution to the current limitation of enzyme instability. By using simple deep eutectic solvents such as choline chloride/sorbitol, significant stabilization of the biocatalyst has been achieved leading to more robust reactions while using environmentally more acceptable solvents as compared to ionic liquids. BT/Biocatalysis Article in Journal/Newspaper Antarc* Antarctica Delft University of Technology: Institutional Repository RSC Advances 7 21 12518 12523
institution Open Polar
collection Delft University of Technology: Institutional Repository
op_collection_id fttudelft
language English
description Epoxides are important synthetic intermediates for the synthesis of a broad range of industrial products. This study presents a promising solution to the current limitation of enzyme instability. By using simple deep eutectic solvents such as choline chloride/sorbitol, significant stabilization of the biocatalyst has been achieved leading to more robust reactions while using environmentally more acceptable solvents as compared to ionic liquids. BT/Biocatalysis
format Article in Journal/Newspaper
author Zhou, Pengfei (author)
Wang, Xuping (author)
Yang, Bo (author)
Hollmann, F. (author)
Wang, Yonghua (author)
spellingShingle Zhou, Pengfei (author)
Wang, Xuping (author)
Yang, Bo (author)
Hollmann, F. (author)
Wang, Yonghua (author)
Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
author_facet Zhou, Pengfei (author)
Wang, Xuping (author)
Yang, Bo (author)
Hollmann, F. (author)
Wang, Yonghua (author)
author_sort Zhou, Pengfei (author)
title Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
title_short Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
title_full Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
title_fullStr Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
title_full_unstemmed Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents
title_sort chemoenzymatic epoxidation of alkenes with candida antarctica lipase b and hydrogen peroxide in deep eutectic solvents
publishDate 2017
url http://resolver.tudelft.nl/uuid:a472564f-492d-4094-8de3-fdf53a84d095
https://doi.org/10.1039/c7ra00805h
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_relation http://resolver.tudelft.nl/uuid:a472564f-492d-4094-8de3-fdf53a84d095
RSC Advances--2046-2069--c5717579-38c9-4252-9db0-b73a9948d660
https://doi.org/10.1039/c7ra00805h
op_rights © 2017 Pengfei Zhou, Xuping Wang, Bo Yang, F. Hollmann, Yonghua Wang
op_doi https://doi.org/10.1039/c7ra00805h
container_title RSC Advances
container_volume 7
container_issue 21
container_start_page 12518
op_container_end_page 12523
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