An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats
Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of pro...
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2020
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Online Access: | https://doi.org/10.1177/1178630220942240 https://doaj.org/article/000c06dc828f4c0db2b2ccfbff62358e |
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fttriple:oai:gotriple.eu:oai:doaj.org/article:000c06dc828f4c0db2b2ccfbff62358e 2023-05-15T18:05:34+02:00 An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats Lorina Badger-Emeka Yasmeen Al-Mulhim Fatimah Al-Muyidi Maram Busuhail Salma Alkhalifah Norah AlEid 2020-08-01 https://doi.org/10.1177/1178630220942240 https://doaj.org/article/000c06dc828f4c0db2b2ccfbff62358e en eng SAGE Publishing 1178-6302 doi:10.1177/1178630220942240 https://doaj.org/article/000c06dc828f4c0db2b2ccfbff62358e undefined Environmental Health Insights, Vol 14 (2020) envir demo Journal Article https://vocabularies.coar-repositories.org/resource_types/c_6501/ 2020 fttriple https://doi.org/10.1177/1178630220942240 2023-01-22T18:03:26Z Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of providing insights for antimicrobial surveillance. Method: Farm rats of Rattus rattus species where randomly collected alive from farms in Al-Ahsa using food baits. They were anaesthetize with urethane within 4 h of collection and were unconscious for the collection of samples. Basic bacteriological culturing methods were used for culturing of bacterial isolates on selective media while the Vitek 2 compact automated system (BioMerieux, Marcy L’Etoile, France) was used for bacteria identification and antimicrobial susceptibility test. Obtained data were analysed using chi-square and paired t -test with significant difference between sensitive and resistance to antimicrobial susceptibility taken at P < .05. Results: Isolated Gramme-negative pathogenic bacteria included strains of Escherichia coli, Pseudomonas oryzihabitans , strains of Pseudomonas aeruginosa , and Salmonella. For the Gramme-positive bacteria, 4 strains of Staphylococcus aureus were encountered. Other Gramme-positive bacteria were coagulase-negative Staphylococcal species (CoNS) as well as Staphylococcus lugdunensis . There was a 100% resistance to the penicillins and a high resistance to imipenem (71%) by the Staphylococcal isolates. Resistance was also high against the β-lactams by the Gramme-positive bacteria isolates. For the Gramme-negative bacteria, there was a higher than 50% resistance by the isolates against the following antibiotics: ampicillin (78%), amoxicillin/clavulanic acid (67%), cefotaxime (77%), ceftazidime (67%), cefepime (78%), norfloxacin (67%), nitrofurantoin (67%), and trimethoprim/sulfamethoxazole (78%). Conclusion: The results showed high antimicrobial resistance that will need monitoring for control of spread from farm rats to ... Article in Journal/Newspaper Rattus rattus Unknown Environmental Health Insights 14 117863022094224 |
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envir demo Lorina Badger-Emeka Yasmeen Al-Mulhim Fatimah Al-Muyidi Maram Busuhail Salma Alkhalifah Norah AlEid An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
topic_facet |
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description |
Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of providing insights for antimicrobial surveillance. Method: Farm rats of Rattus rattus species where randomly collected alive from farms in Al-Ahsa using food baits. They were anaesthetize with urethane within 4 h of collection and were unconscious for the collection of samples. Basic bacteriological culturing methods were used for culturing of bacterial isolates on selective media while the Vitek 2 compact automated system (BioMerieux, Marcy L’Etoile, France) was used for bacteria identification and antimicrobial susceptibility test. Obtained data were analysed using chi-square and paired t -test with significant difference between sensitive and resistance to antimicrobial susceptibility taken at P < .05. Results: Isolated Gramme-negative pathogenic bacteria included strains of Escherichia coli, Pseudomonas oryzihabitans , strains of Pseudomonas aeruginosa , and Salmonella. For the Gramme-positive bacteria, 4 strains of Staphylococcus aureus were encountered. Other Gramme-positive bacteria were coagulase-negative Staphylococcal species (CoNS) as well as Staphylococcus lugdunensis . There was a 100% resistance to the penicillins and a high resistance to imipenem (71%) by the Staphylococcal isolates. Resistance was also high against the β-lactams by the Gramme-positive bacteria isolates. For the Gramme-negative bacteria, there was a higher than 50% resistance by the isolates against the following antibiotics: ampicillin (78%), amoxicillin/clavulanic acid (67%), cefotaxime (77%), ceftazidime (67%), cefepime (78%), norfloxacin (67%), nitrofurantoin (67%), and trimethoprim/sulfamethoxazole (78%). Conclusion: The results showed high antimicrobial resistance that will need monitoring for control of spread from farm rats to ... |
format |
Article in Journal/Newspaper |
author |
Lorina Badger-Emeka Yasmeen Al-Mulhim Fatimah Al-Muyidi Maram Busuhail Salma Alkhalifah Norah AlEid |
author_facet |
Lorina Badger-Emeka Yasmeen Al-Mulhim Fatimah Al-Muyidi Maram Busuhail Salma Alkhalifah Norah AlEid |
author_sort |
Lorina Badger-Emeka |
title |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_short |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_full |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_fullStr |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_full_unstemmed |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_sort |
investigation of potential health risks from zoonotic bacterial pathogens associated with farm rats |
publisher |
SAGE Publishing |
publishDate |
2020 |
url |
https://doi.org/10.1177/1178630220942240 https://doaj.org/article/000c06dc828f4c0db2b2ccfbff62358e |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Environmental Health Insights, Vol 14 (2020) |
op_relation |
1178-6302 doi:10.1177/1178630220942240 https://doaj.org/article/000c06dc828f4c0db2b2ccfbff62358e |
op_rights |
undefined |
op_doi |
https://doi.org/10.1177/1178630220942240 |
container_title |
Environmental Health Insights |
container_volume |
14 |
container_start_page |
117863022094224 |
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1766177046209232896 |