Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.

• Published in: npj Primary Care Respiratory Medicine
• Main Authors: Andreeva, Elena, Pokhaznikova, Marina, Lebedev, Anatoly, Moiseeva, Irina, Kuznetsova, Olga, Degryse, Jean-Marie
• Other Authors: UCL - SSS/IRSS - Institut de recherche santé et société, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies
• Format: Article in Journal/Newspaper
• Language: English
• Published: Nature Publishing Group 2017
• Subjects: socio; hist; North-Western Russia
• Online Access: https://doi.org/10.1038/s41533-017-0062-6; http://hdl.handle.net/2078.1/189886

A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD diagnosis has been based on spirometry and a few clinical characteristics. The aim of our study was to identify outcomes in patients newly diagnosed with airflow obstruction (AO) based on a diagnostic work-up conducted as part of a population-based cross-sectional study in North-Western Russia. Spirometry was performed before (pre-BD) and after BD administration, and AO was defined using the FEV1/FVC <0.70 and FEV1/FVC