Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn
Northern freshwater fish may be suitable for the genetic dissection of ecological traits because they invaded new habitats after the last ice age (~10.000 years ago). Arctic charr (Salvelinus alpinus) colonizing streams and lakes in Iceland gave rise to multiple populations of small benthic morphoty...
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fttriple:oai:gotriple.eu:50|dedup_wf_001::99404d8524cac4905387d860cda91ae5 2023-05-15T14:30:00+02:00 Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn Kapralova, Kalina H. Gudbrandsson, Johannes Reynisdottir, Sigrun Santos, Cristina B. Baltanás, Vanessa C. Maier, Valerie H. Snorrason, Sigurdur S. Palsson, Arnar 2013-01-01 https://doi.org/10.5061/dryad.81884 undefined unknown http://dx.doi.org/10.5061/dryad.81884 https://dx.doi.org/10.5061/dryad.81884 lic_creative-commons oai:services.nod.dans.knaw.nl:Products/dans:oai:easy.dans.knaw.nl:easy-dataset:83919 10.5061/dryad.81884 oai:easy.dans.knaw.nl:easy-dataset:83919 10|eurocrisdris::fe4903425d9040f680d8610d9079ea14 10|openaire____::9e3be59865b2c1c335d32dae2fe7b254 10|re3data_____::94816e6421eeb072e7742ce6a9decc5f 10|openaire____::081b82f96300b6a6e3d282bad31cb6e2 re3data_____::r3d100000044 10|re3data_____::84e123776089ce3c7a33db98d9cd15a8 10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c Life sciences medicine and health care salmonidae Euteleostei Immunology FOS: Clinical medicine Parasites association test Salvelinus alpinus evolutionary genetics Iceland envir geo Dataset https://vocabularies.coar-repositories.org/resource_types/c_ddb1/ 2013 fttriple https://doi.org/10.5061/dryad.81884 2023-01-22T16:52:56Z Northern freshwater fish may be suitable for the genetic dissection of ecological traits because they invaded new habitats after the last ice age (~10.000 years ago). Arctic charr (Salvelinus alpinus) colonizing streams and lakes in Iceland gave rise to multiple populations of small benthic morphotypes, often in sympatry with a pelagic morphotype. Earlier studies have revealed significant, but subtle, genetic differentiation between the three most common morphs in Lake Thingvallavatn. We conducted a population genetic screen on four immunological candidate genes Cathelicidin 2 (Cath2), Hepcidin (Hamp), Liver expressed antimicrobial peptide 2a (Leap-2a), and Major Histocompatibility Complex IIα (MHCIIα) and a mitochondrial marker (D-loop) among the three most common Lake Thingvallavatn charr morphs. Significant differences in allele frequencies were found between morphs at the Cath2 and MHCIIα loci. No such signal was detected in the D-loop nor in the other two immunological genes. In Cath2 the small benthic morph deviated from the other two (FST = 0.13), one of the substitutions detected constituting an amino acid replacement polymorphism in the antimicrobial peptide. A more striking difference was found in the MHCIIα. Two haplotypes were very common in the lake, and their frequency differed greatly between the morphotypes (from 22% to 93.5%, FST = 0.67). We then expanded our study by surveying the variation in Cath2 and MHCIIα in 9 Arctic charr populations from around Iceland. The populations varied greatly in terms of allele frequencies at Cath2, but the variation did not correlate with morphotype. At the MHCIIα locus, the variation was nearly identical to the variation in the two benthic morphs of Lake Thingvallavatn. The results are consistent with a scenario where parts of the immune systems have diverged substantially among Arctic charr populations in Iceland, after colonizing the island ~10.000 years ago. Kapralova2013_Charr2005Dataset 1 – Arctic Charr from Lake Thingvallavatn, collected in 2005. ... Dataset Arctic charr Arctic Iceland Salvelinus alpinus Unknown Arctic |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
fttriple |
language |
unknown |
topic |
Life sciences medicine and health care salmonidae Euteleostei Immunology FOS: Clinical medicine Parasites association test Salvelinus alpinus evolutionary genetics Iceland envir geo |
spellingShingle |
Life sciences medicine and health care salmonidae Euteleostei Immunology FOS: Clinical medicine Parasites association test Salvelinus alpinus evolutionary genetics Iceland envir geo Kapralova, Kalina H. Gudbrandsson, Johannes Reynisdottir, Sigrun Santos, Cristina B. Baltanás, Vanessa C. Maier, Valerie H. Snorrason, Sigurdur S. Palsson, Arnar Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
topic_facet |
Life sciences medicine and health care salmonidae Euteleostei Immunology FOS: Clinical medicine Parasites association test Salvelinus alpinus evolutionary genetics Iceland envir geo |
description |
Northern freshwater fish may be suitable for the genetic dissection of ecological traits because they invaded new habitats after the last ice age (~10.000 years ago). Arctic charr (Salvelinus alpinus) colonizing streams and lakes in Iceland gave rise to multiple populations of small benthic morphotypes, often in sympatry with a pelagic morphotype. Earlier studies have revealed significant, but subtle, genetic differentiation between the three most common morphs in Lake Thingvallavatn. We conducted a population genetic screen on four immunological candidate genes Cathelicidin 2 (Cath2), Hepcidin (Hamp), Liver expressed antimicrobial peptide 2a (Leap-2a), and Major Histocompatibility Complex IIα (MHCIIα) and a mitochondrial marker (D-loop) among the three most common Lake Thingvallavatn charr morphs. Significant differences in allele frequencies were found between morphs at the Cath2 and MHCIIα loci. No such signal was detected in the D-loop nor in the other two immunological genes. In Cath2 the small benthic morph deviated from the other two (FST = 0.13), one of the substitutions detected constituting an amino acid replacement polymorphism in the antimicrobial peptide. A more striking difference was found in the MHCIIα. Two haplotypes were very common in the lake, and their frequency differed greatly between the morphotypes (from 22% to 93.5%, FST = 0.67). We then expanded our study by surveying the variation in Cath2 and MHCIIα in 9 Arctic charr populations from around Iceland. The populations varied greatly in terms of allele frequencies at Cath2, but the variation did not correlate with morphotype. At the MHCIIα locus, the variation was nearly identical to the variation in the two benthic morphs of Lake Thingvallavatn. The results are consistent with a scenario where parts of the immune systems have diverged substantially among Arctic charr populations in Iceland, after colonizing the island ~10.000 years ago. Kapralova2013_Charr2005Dataset 1 – Arctic Charr from Lake Thingvallavatn, collected in 2005. ... |
format |
Dataset |
author |
Kapralova, Kalina H. Gudbrandsson, Johannes Reynisdottir, Sigrun Santos, Cristina B. Baltanás, Vanessa C. Maier, Valerie H. Snorrason, Sigurdur S. Palsson, Arnar |
author_facet |
Kapralova, Kalina H. Gudbrandsson, Johannes Reynisdottir, Sigrun Santos, Cristina B. Baltanás, Vanessa C. Maier, Valerie H. Snorrason, Sigurdur S. Palsson, Arnar |
author_sort |
Kapralova, Kalina H. |
title |
Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
title_short |
Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
title_full |
Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
title_fullStr |
Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
title_full_unstemmed |
Data from: Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn |
title_sort |
data from: differentiation at the mhciiα and cath2 loci in sympatric salvelinus alpinus resource morphs in lake thingvallavatn |
publishDate |
2013 |
url |
https://doi.org/10.5061/dryad.81884 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic charr Arctic Iceland Salvelinus alpinus |
genre_facet |
Arctic charr Arctic Iceland Salvelinus alpinus |
op_source |
oai:services.nod.dans.knaw.nl:Products/dans:oai:easy.dans.knaw.nl:easy-dataset:83919 10.5061/dryad.81884 oai:easy.dans.knaw.nl:easy-dataset:83919 10|eurocrisdris::fe4903425d9040f680d8610d9079ea14 10|openaire____::9e3be59865b2c1c335d32dae2fe7b254 10|re3data_____::94816e6421eeb072e7742ce6a9decc5f 10|openaire____::081b82f96300b6a6e3d282bad31cb6e2 re3data_____::r3d100000044 10|re3data_____::84e123776089ce3c7a33db98d9cd15a8 10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c |
op_relation |
http://dx.doi.org/10.5061/dryad.81884 https://dx.doi.org/10.5061/dryad.81884 |
op_rights |
lic_creative-commons |
op_doi |
https://doi.org/10.5061/dryad.81884 |
_version_ |
1766303939627581440 |