Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon
Males and females share many traits that have a common genetic basis; however, selection on these traits often differs between the sexes, leading to sexual conflict. Under such sexual antagonism, theory predicts the evolution of genetic architectures that resolve this sexual conflict. Yet, despite i...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Dataset |
Language: | unknown |
Published: |
Data Archiving and Networked Services (DANS)
2015
|
Subjects: | |
Online Access: | https://doi.org/10.5061/dryad.23h4q |
id |
fttriple:oai:gotriple.eu:50|dedup_wf_001::6e5efda230d60e99117e45b3e84e46ef |
---|---|
record_format |
openpolar |
spelling |
fttriple:oai:gotriple.eu:50|dedup_wf_001::6e5efda230d60e99117e45b3e84e46ef 2023-05-15T15:32:53+02:00 Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon Barson, Nicola J. Aykanat, Tuku Hindar, Kjetil Baranski, Matthew Bolstad, Geir H. Fiske, Peder Jacq, Céleste Jensen, Arne J. Johnston, Susan E. Karlsson, Sten Kent, Matthew Moen, Thomas Niemelä, Eero Nome, Torfinn Næsje, Tor F. Orell, Panu Romakkaniemi, Atso Sægrov, Harald Urdal, Kurt Erkinaro, Jaakko Lien, Sigbjørn Primmer, Craig R. 2015-01-01 https://doi.org/10.5061/dryad.23h4q undefined unknown Data Archiving and Networked Services (DANS) http://dx.doi.org/10.5061/dryad.23h4q https://dx.doi.org/10.5061/dryad.23h4q lic_creative-commons oai:easy.dans.knaw.nl:easy-dataset:91139 oai:services.nod.dans.knaw.nl:Products/dans:oai:easy.dans.knaw.nl:easy-dataset:91139 10.5061/dryad.23h4q 10|re3data_____::84e123776089ce3c7a33db98d9cd15a8 10|eurocrisdris::fe4903425d9040f680d8610d9079ea14 10|openaire____::081b82f96300b6a6e3d282bad31cb6e2 re3data_____::r3d100000044 10|openaire____::9e3be59865b2c1c335d32dae2fe7b254 10|re3data_____::94816e6421eeb072e7742ce6a9decc5f 10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c Life sciences medicine and health care local adaptation population genetics sexual conflict GWAS Salmo salar age at maturity fisheries evolutionary genetics Norway Finland psy envir Dataset https://vocabularies.coar-repositories.org/resource_types/c_ddb1/ 2015 fttriple https://doi.org/10.5061/dryad.23h4q 2023-01-22T17:16:28Z Males and females share many traits that have a common genetic basis; however, selection on these traits often differs between the sexes, leading to sexual conflict. Under such sexual antagonism, theory predicts the evolution of genetic architectures that resolve this sexual conflict. Yet, despite intense theoretical and empirical interest, the specific loci underlying sexually antagonistic phenotypes have rarely been identified, limiting our understanding of how sexual conflict impacts genome evolution and the maintenance of genetic diversity. Here we identify a large effect locus controlling age at maturity in Atlantic salmon (Salmo salar), an important fitness trait in which selection favours earlier maturation in males than females and show it is a clear example of sex-dependent dominance that reduces intralocus sexual conflict and maintains adaptive variation in wild populations. Using high-density single nucleotide polymorphism data across 57 wild populations and whole genome re-sequencing, we find that the vestigial-like family member 3 gene (VGLL3) exhibits sex-dependent dominance in salmon, promoting earlier and later maturation in males and females, respectively. VGLL3, an adiposity regulator associated with size and age at maturity in humans, explained 39% of phenotypic variation, an unexpectedly large proportion for what is usually considered a highly polygenic trait. Such large effects are predicted under balancing selection from either sexually antagonistic or spatially varying selection. Our results provide the first empirical example of dominance reversal allowing greater optimization of phenotypes within each sex, contributing to the resolution of sexual conflict in a major and widespread evolutionary trade-off between age and size at maturity. They also provide key empirical evidence for how variation in reproductive strategies can be maintained over large geographical scales. We anticipate these findings will have a substantial impact on population management in a range of harvested species ... Dataset Atlantic salmon Salmo salar Unknown Norway |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
fttriple |
language |
unknown |
topic |
Life sciences medicine and health care local adaptation population genetics sexual conflict GWAS Salmo salar age at maturity fisheries evolutionary genetics Norway Finland psy envir |
spellingShingle |
Life sciences medicine and health care local adaptation population genetics sexual conflict GWAS Salmo salar age at maturity fisheries evolutionary genetics Norway Finland psy envir Barson, Nicola J. Aykanat, Tuku Hindar, Kjetil Baranski, Matthew Bolstad, Geir H. Fiske, Peder Jacq, Céleste Jensen, Arne J. Johnston, Susan E. Karlsson, Sten Kent, Matthew Moen, Thomas Niemelä, Eero Nome, Torfinn Næsje, Tor F. Orell, Panu Romakkaniemi, Atso Sægrov, Harald Urdal, Kurt Erkinaro, Jaakko Lien, Sigbjørn Primmer, Craig R. Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
topic_facet |
Life sciences medicine and health care local adaptation population genetics sexual conflict GWAS Salmo salar age at maturity fisheries evolutionary genetics Norway Finland psy envir |
description |
Males and females share many traits that have a common genetic basis; however, selection on these traits often differs between the sexes, leading to sexual conflict. Under such sexual antagonism, theory predicts the evolution of genetic architectures that resolve this sexual conflict. Yet, despite intense theoretical and empirical interest, the specific loci underlying sexually antagonistic phenotypes have rarely been identified, limiting our understanding of how sexual conflict impacts genome evolution and the maintenance of genetic diversity. Here we identify a large effect locus controlling age at maturity in Atlantic salmon (Salmo salar), an important fitness trait in which selection favours earlier maturation in males than females and show it is a clear example of sex-dependent dominance that reduces intralocus sexual conflict and maintains adaptive variation in wild populations. Using high-density single nucleotide polymorphism data across 57 wild populations and whole genome re-sequencing, we find that the vestigial-like family member 3 gene (VGLL3) exhibits sex-dependent dominance in salmon, promoting earlier and later maturation in males and females, respectively. VGLL3, an adiposity regulator associated with size and age at maturity in humans, explained 39% of phenotypic variation, an unexpectedly large proportion for what is usually considered a highly polygenic trait. Such large effects are predicted under balancing selection from either sexually antagonistic or spatially varying selection. Our results provide the first empirical example of dominance reversal allowing greater optimization of phenotypes within each sex, contributing to the resolution of sexual conflict in a major and widespread evolutionary trade-off between age and size at maturity. They also provide key empirical evidence for how variation in reproductive strategies can be maintained over large geographical scales. We anticipate these findings will have a substantial impact on population management in a range of harvested species ... |
format |
Dataset |
author |
Barson, Nicola J. Aykanat, Tuku Hindar, Kjetil Baranski, Matthew Bolstad, Geir H. Fiske, Peder Jacq, Céleste Jensen, Arne J. Johnston, Susan E. Karlsson, Sten Kent, Matthew Moen, Thomas Niemelä, Eero Nome, Torfinn Næsje, Tor F. Orell, Panu Romakkaniemi, Atso Sægrov, Harald Urdal, Kurt Erkinaro, Jaakko Lien, Sigbjørn Primmer, Craig R. |
author_facet |
Barson, Nicola J. Aykanat, Tuku Hindar, Kjetil Baranski, Matthew Bolstad, Geir H. Fiske, Peder Jacq, Céleste Jensen, Arne J. Johnston, Susan E. Karlsson, Sten Kent, Matthew Moen, Thomas Niemelä, Eero Nome, Torfinn Næsje, Tor F. Orell, Panu Romakkaniemi, Atso Sægrov, Harald Urdal, Kurt Erkinaro, Jaakko Lien, Sigbjørn Primmer, Craig R. |
author_sort |
Barson, Nicola J. |
title |
Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
title_short |
Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
title_full |
Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
title_fullStr |
Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
title_full_unstemmed |
Data from: Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
title_sort |
data from: sex-dependent dominance at a single locus maintains variation in age at maturity in salmon |
publisher |
Data Archiving and Networked Services (DANS) |
publishDate |
2015 |
url |
https://doi.org/10.5061/dryad.23h4q |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
oai:easy.dans.knaw.nl:easy-dataset:91139 oai:services.nod.dans.knaw.nl:Products/dans:oai:easy.dans.knaw.nl:easy-dataset:91139 10.5061/dryad.23h4q 10|re3data_____::84e123776089ce3c7a33db98d9cd15a8 10|eurocrisdris::fe4903425d9040f680d8610d9079ea14 10|openaire____::081b82f96300b6a6e3d282bad31cb6e2 re3data_____::r3d100000044 10|openaire____::9e3be59865b2c1c335d32dae2fe7b254 10|re3data_____::94816e6421eeb072e7742ce6a9decc5f 10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c |
op_relation |
http://dx.doi.org/10.5061/dryad.23h4q https://dx.doi.org/10.5061/dryad.23h4q |
op_rights |
lic_creative-commons |
op_doi |
https://doi.org/10.5061/dryad.23h4q |
_version_ |
1766363359694815232 |