Data from: Mitochondrial capture by a transmissible cancer

• Main Authors: Rebbeck, Clare A., Leroi, Armand M., Burt, Austin
• Format: Dataset
• Language: English
• Published: Dryad 2010
• Subjects: Canis lupus familiaris; Mitochondria; Canis latrans; Canis lupus; Canine transmissible cancer; Life sciences; medicine and health care; Mexico; Israel; South Africa; Thailand; Kenya; Malaysia; Greece; psy; geo
• Online Access: https://doi.org/10.5061/dryad.8081

Canine transmissible venereal tumor (CTVT) is an infectious cell line circulating in many feral dog populations. It originated once, about 10,000 years ago. Phylogenetic analyses of mitochondrial sequences from dogs, wolves, and a geographically diverse collection of CTVT samples indicate that the cancer has periodically acquired mitochondria from its host. We suggest that this may be because the cancer’s own mitochondria have a tendency to degenerate, due to high mutation rates and relaxed selection, resulting in host mitochondria being more fit. Rebbeck phylogenyNexus file for phylogenetic tree of mitochondrial sequence data. Data collected from canine transmissible venereal tumor and host dog aligned with dog, wolf and coyote sequences.