Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence
Specialization: Health Promotion and Socio-Behavioural Sciences Degree: Master of Science Abstract: BACKGROUND: In Canada, preventive therapy for LTBI has meant long durations and frequent dosing. This contributes to poor adherence and completion rates. In response, a shortened treatment regimen, on...
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University of Alberta. School of Public Health.
2020
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fttriple:oai:gotriple.eu:10670/1.zgwb01 2023-05-15T16:17:40+02:00 Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence Heyd, Amber T Long, Richard (School of Public Health, Faculty of Medicine and Dentistry) Wild, Thomas Cameron (School of Public Health) 2020-09-28 https://era.library.ualberta.ca/items/7e7261f1-091b-4089-a4a9-044660aa1430 en eng University of Alberta. School of Public Health. 10670/1.zgwb01 https://era.library.ualberta.ca/items/7e7261f1-091b-4089-a4a9-044660aa1430 undefined ERA : Education and Research Archive anthro-bio demo Thesis https://vocabularies.coar-repositories.org/resource_types/c_46ec/ 2020 fttriple 2023-01-22T18:41:02Z Specialization: Health Promotion and Socio-Behavioural Sciences Degree: Master of Science Abstract: BACKGROUND: In Canada, preventive therapy for LTBI has meant long durations and frequent dosing. This contributes to poor adherence and completion rates. In response, a shortened treatment regimen, once weekly rifapentine plus isoniazid for 3 months (3HP), is now available, though there has been no formal evaluation of it use. This study explored perceptions of latency and the need for preventive therapy, and barriers and facilitators to treatment adherence and completion in inner-city clients offered 3HP and their health care providers. DESIGN/METHODS: This qualitative descriptive study involved semi-structured individual interviews. Unstably housed or homeless individuals in Edmonton and Fort McMurray, Alberta, Canada offered directly observed preventive therapy (DOPT) with 3HP, and their health care providers were eligible. The data were systematically organized and analyzed using latent content analysis. RESULTS: Analysis of interviews revealed incomplete understandings of LTBI and the need for preventive therapy. Clients self-motivation and desire to be healthy, alongside education, health care outreach, relationships through DOPT, ease of treatment regimen, incentives and collaboration were described as supporting successful treatment outcomes. Competing priorities, difficulty in reaching clients, undesirable aspects of the regimen (e.g. side effects, pill burden and drug interactions) and arduousness related to obtaining and initiating 3HP were barriers to access, uptake, and completion. Perceptions of stigma related to LTBI and TB were described by clients as well as feelings of shame or embarrassment related to their diagnosis CONCLUSIONS: This study was the first in Canada to qualitatively explore the use of 3HP. Our study used qualitative descriptive methods to explore the understandings of LTBI and the barriers and facilitators to preventive therapy access, uptake, and adherence among individuals ... Thesis Fort McMurray Unknown Canada Fort McMurray |
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anthro-bio demo Heyd, Amber T Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
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description |
Specialization: Health Promotion and Socio-Behavioural Sciences Degree: Master of Science Abstract: BACKGROUND: In Canada, preventive therapy for LTBI has meant long durations and frequent dosing. This contributes to poor adherence and completion rates. In response, a shortened treatment regimen, once weekly rifapentine plus isoniazid for 3 months (3HP), is now available, though there has been no formal evaluation of it use. This study explored perceptions of latency and the need for preventive therapy, and barriers and facilitators to treatment adherence and completion in inner-city clients offered 3HP and their health care providers. DESIGN/METHODS: This qualitative descriptive study involved semi-structured individual interviews. Unstably housed or homeless individuals in Edmonton and Fort McMurray, Alberta, Canada offered directly observed preventive therapy (DOPT) with 3HP, and their health care providers were eligible. The data were systematically organized and analyzed using latent content analysis. RESULTS: Analysis of interviews revealed incomplete understandings of LTBI and the need for preventive therapy. Clients self-motivation and desire to be healthy, alongside education, health care outreach, relationships through DOPT, ease of treatment regimen, incentives and collaboration were described as supporting successful treatment outcomes. Competing priorities, difficulty in reaching clients, undesirable aspects of the regimen (e.g. side effects, pill burden and drug interactions) and arduousness related to obtaining and initiating 3HP were barriers to access, uptake, and completion. Perceptions of stigma related to LTBI and TB were described by clients as well as feelings of shame or embarrassment related to their diagnosis CONCLUSIONS: This study was the first in Canada to qualitatively explore the use of 3HP. Our study used qualitative descriptive methods to explore the understandings of LTBI and the barriers and facilitators to preventive therapy access, uptake, and adherence among individuals ... |
author2 |
Long, Richard (School of Public Health, Faculty of Medicine and Dentistry) Wild, Thomas Cameron (School of Public Health) |
format |
Thesis |
author |
Heyd, Amber T |
author_facet |
Heyd, Amber T |
author_sort |
Heyd, Amber T |
title |
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
title_short |
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
title_full |
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
title_fullStr |
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
title_full_unstemmed |
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence |
title_sort |
management of latent tuberculosis infection among an inner-city population with psychosocial barriers to treatment adherence |
publisher |
University of Alberta. School of Public Health. |
publishDate |
2020 |
url |
https://era.library.ualberta.ca/items/7e7261f1-091b-4089-a4a9-044660aa1430 |
geographic |
Canada Fort McMurray |
geographic_facet |
Canada Fort McMurray |
genre |
Fort McMurray |
genre_facet |
Fort McMurray |
op_source |
ERA : Education and Research Archive |
op_relation |
10670/1.zgwb01 https://era.library.ualberta.ca/items/7e7261f1-091b-4089-a4a9-044660aa1430 |
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