Adherence and barriers to H. pylori treatment in Arctic Canada.
Introduction. Helicobacter pylori infection is an emerging health concern to some northern Canadian Aboriginal communities and their clinicians. Clinicians in the north perceive H. pylori infection to be a major clinical problem because they find H. pylori infection in many patients evaluated for co...
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fttriple:oai:gotriple.eu:10670/1.ppvlch 2023-05-15T13:08:02+02:00 Adherence and barriers to H. pylori treatment in Arctic Canada. van Zanten, S.V. Chang, H.J. Morse, A. Lefebvre, M. Goodman, K.J. 2014-01-01 https://doi.org/10.7939/R38911Q90 https://era.library.ualberta.ca/items/3b8458bd-badf-4ac3-b0e6-04a7025b7812 en eng doi:10.7939/R38911Q90 10670/1.ppvlch https://era.library.ualberta.ca/items/3b8458bd-badf-4ac3-b0e6-04a7025b7812 lic_creative-commons ERA : Education and Research Archive psy demo Other https://vocabularies.coar-repositories.org/resource_types/c_1843/ 2014 fttriple https://doi.org/10.7939/R38911Q90 2023-01-22T18:30:46Z Introduction. Helicobacter pylori infection is an emerging health concern to some northern Canadian Aboriginal communities and their clinicians. Clinicians in the north perceive H. pylori infection to be a major clinical problem because they find H. pylori infection in many patients evaluated for common stomach complaints, leading to frequent demand for treatment, which often fails. Moreover, public health authorities identified the need for information to develop locally appropriate H. pylori control strategies. We described adherence and identified barriers to completing treatment among H. pylori-positive participants in a community-based project inspired by local concerns about H. pylori infection risks. Methods. In 2008, 110 H. pylori-positive participants (diagnosed by a breath test, histopathology and/or culture) of the Aklavik H. pylori project were randomised to standard-of-care or sequential treatment. We ascertained adherence by interviewing participants using a structured questionnaire. We estimated adherence frequencies as the proportion of participants who reported taking either 100% of doses (perfect adherence) or ≥80% of doses (good adherence). To compare the proportion with perfect or good adherence in subgroups, we report proportion differences and 95% confidence intervals (CI). Results. Of 87 participants who were interviewed, 64% reported perfect adherence and 80% reported good adherence. We observed more frequent perfect adherence for: standard therapy (67%) versus sequential (62%); males (76%) versus females (52%); participants 40–77 years (79%) versus 17–39 (50%). Proportion differences were 5% (CI: −15, 25) for standard versus sequential therapy; 23% (CI: 4, 43) for male versus female; and 29% (CI: 10, 48) for 40–77 versus 15–39 years for perfect adherence. Of the 29 participants who reported poor adherence (<80% of doses taken), the following barriers to treatment were reported: changed mind about taking treatment (24%), consumption of alcoholic beverages (18%), nausea (18%), ... Other/Unknown Material Aklavik Arctic Unknown Aklavik ENVELOPE(-135.011,-135.011,68.219,68.219) Arctic Canada |
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psy demo van Zanten, S.V. Chang, H.J. Morse, A. Lefebvre, M. Goodman, K.J. Adherence and barriers to H. pylori treatment in Arctic Canada. |
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description |
Introduction. Helicobacter pylori infection is an emerging health concern to some northern Canadian Aboriginal communities and their clinicians. Clinicians in the north perceive H. pylori infection to be a major clinical problem because they find H. pylori infection in many patients evaluated for common stomach complaints, leading to frequent demand for treatment, which often fails. Moreover, public health authorities identified the need for information to develop locally appropriate H. pylori control strategies. We described adherence and identified barriers to completing treatment among H. pylori-positive participants in a community-based project inspired by local concerns about H. pylori infection risks. Methods. In 2008, 110 H. pylori-positive participants (diagnosed by a breath test, histopathology and/or culture) of the Aklavik H. pylori project were randomised to standard-of-care or sequential treatment. We ascertained adherence by interviewing participants using a structured questionnaire. We estimated adherence frequencies as the proportion of participants who reported taking either 100% of doses (perfect adherence) or ≥80% of doses (good adherence). To compare the proportion with perfect or good adherence in subgroups, we report proportion differences and 95% confidence intervals (CI). Results. Of 87 participants who were interviewed, 64% reported perfect adherence and 80% reported good adherence. We observed more frequent perfect adherence for: standard therapy (67%) versus sequential (62%); males (76%) versus females (52%); participants 40–77 years (79%) versus 17–39 (50%). Proportion differences were 5% (CI: −15, 25) for standard versus sequential therapy; 23% (CI: 4, 43) for male versus female; and 29% (CI: 10, 48) for 40–77 versus 15–39 years for perfect adherence. Of the 29 participants who reported poor adherence (<80% of doses taken), the following barriers to treatment were reported: changed mind about taking treatment (24%), consumption of alcoholic beverages (18%), nausea (18%), ... |
format |
Other/Unknown Material |
author |
van Zanten, S.V. Chang, H.J. Morse, A. Lefebvre, M. Goodman, K.J. |
author_facet |
van Zanten, S.V. Chang, H.J. Morse, A. Lefebvre, M. Goodman, K.J. |
author_sort |
van Zanten, S.V. |
title |
Adherence and barriers to H. pylori treatment in Arctic Canada. |
title_short |
Adherence and barriers to H. pylori treatment in Arctic Canada. |
title_full |
Adherence and barriers to H. pylori treatment in Arctic Canada. |
title_fullStr |
Adherence and barriers to H. pylori treatment in Arctic Canada. |
title_full_unstemmed |
Adherence and barriers to H. pylori treatment in Arctic Canada. |
title_sort |
adherence and barriers to h. pylori treatment in arctic canada. |
publishDate |
2014 |
url |
https://doi.org/10.7939/R38911Q90 https://era.library.ualberta.ca/items/3b8458bd-badf-4ac3-b0e6-04a7025b7812 |
long_lat |
ENVELOPE(-135.011,-135.011,68.219,68.219) |
geographic |
Aklavik Arctic Canada |
geographic_facet |
Aklavik Arctic Canada |
genre |
Aklavik Arctic |
genre_facet |
Aklavik Arctic |
op_source |
ERA : Education and Research Archive |
op_relation |
doi:10.7939/R38911Q90 10670/1.ppvlch https://era.library.ualberta.ca/items/3b8458bd-badf-4ac3-b0e6-04a7025b7812 |
op_rights |
lic_creative-commons |
op_doi |
https://doi.org/10.7939/R38911Q90 |
_version_ |
1766072448522911744 |