STROKE MODIFIED RISK FACTORS IN THE MULTIETNIC POPULATION OF YAKUTIA

• Format: Other/Unknown Material
• Language: English
• Published: Morressier 2017
• Subjects: demo; envir; Chugunova; Yakutsk; Yakutia
• Online Access: https://doi.org/10.26226/morressier.5cb58cfcc668520010b56c99; https://openresearchlibrary.org/ext/api/media/16edecf3-31d0-4cb5-bfb9-4216c0f2afbe/assets/external_content.pdf; https://openresearchlibrary.org/viewer/16edecf3-31d0-4cb5-bfb9-4216c0f2afbe

STROKE MODIFIED RISK FACTORS IN THE MULTIETNIC POPULATION OF YAKUTIAS.A. Chugunova 1, O.A. Klochikhina 2, L.V. Stakhovskaya 2, T.Ya. Nikolaeva1, O.A.Gorokhova 11 North-Eastern Federal University, Yakutsk2 Pirogov Russian National Research Medical University, MoscowBackground and Aims. The stroke risk factor's study in different racial-ethnic groups living in identical climatic, geographical and socio-economic conditions is actual for understanding of stroke pathogenesis. The aim of this study was to estimate the stroke modifiable risk factor's prevalence in various racial groups of Yakutia. Methods. The method of population-based stroke register (National Stroke Association, Russia) was used in this study. The study included all residents of Yakutsk city aged 25 and older with an acute stroke registered in 2015-2017 (n=2171). Patients of the two most common racial groups of Yakutia (Caucasians (n=1031; 47.5%) and indigenous Asian ethnic groups (n=1140; 52.5%) were included in the study. Results. The most frequent risk factor was arterial hypertension (99% in Caucasians vs. 98.1% in Asians; p=0.085).There were other studied risk factors: smoking (32.7% vs. 26.3%; p=0.002; OR=1.360; 95% CI: 1.119-1.652); heart diseases (72.6% vs. 64.9%; p<0.0001; OR=1.430; 95% CI: 1.184-1.727); atrial fibrillation (28.5% vs. 22.7%; p=0.002; OR=1.352; 95% CI: 1.107-1.650); history of myocardial infarction (24.4% vs. 14.5%; p <0.0001; OR=1.901; 95% CI: 1.518-2.382); dyslipidemia (54.6% vs. 50.6%; p=0.084); diabetes mellitus (18.3% vs. 17.3%; p=0.560); stress (3.7% vs. 3.5%; p=0.881), respectively.Conclusion. The prevalence of such modifiable stroke risk factors as smoking, heart disease, atrial fibrillation and history of myocardial infarction are significantly higher among Caucasian stroke patients compared to the indigenous Asian ethnic group's stroke patients in Yakutia. The established data reflect the probably existing stroke pathogenesis features in different racial groups.