Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity
Rutin was enzymatically acylated with hexadecanedioic acid, in tert‐amyl alcohol, by an immobilized lipase from Candida antartica “Novozym 435”. The effect of different techniques of water removal, temperature, concentration of rutin and diacid/rutin molar ratio was investigated. The obtained result...
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fttriple:oai:gotriple.eu:10670/1.eer8rf 2023-05-15T14:15:46+02:00 Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity Slimane, Manel 2017-01-01 https://doi.org/10.5772/67621 https://openresearchlibrary.org/ext/api/media/fbb5d244-8c7f-4b42-b666-6f9283f70be6/assets/external_content.pdf https://openresearchlibrary.org/viewer/fbb5d244-8c7f-4b42-b666-6f9283f70be6 en eng IntechOpen ISBN:9789535134237 doi:10.5772/67621 10670/1.eer8rf https://openresearchlibrary.org/ext/api/media/fbb5d244-8c7f-4b42-b666-6f9283f70be6/assets/external_content.pdf https://openresearchlibrary.org/viewer/fbb5d244-8c7f-4b42-b666-6f9283f70be6 lic_creative-commons Open Research Library envir manag Book https://vocabularies.coar-repositories.org/resource_types/c_2f33/ 2017 fttriple https://doi.org/10.5772/67621 2023-01-22T17:10:13Z Rutin was enzymatically acylated with hexadecanedioic acid, in tert‐amyl alcohol, by an immobilized lipase from Candida antartica “Novozym 435”. The effect of different techniques of water removal, temperature, concentration of rutin and diacid/rutin molar ratio was investigated. The obtained results indicated that drying the media by adding the molecular sieves in the outer loop of the reactor was the most efficient method leading to water content lower than 200 ppm. The highest performances (conversion yield and initial rate) were reached at 90°C, 131 mM of rutin, and 118 mM of acid. Depending on the water content and the diacid/rutin molar ratio, only rutin 4‴‐hexadecanedioate or both rutin 4‴‐hexadecanedioate and dirutin 4‴, 4‴‐hexadecanedioate were synthesized. Book antartic* Unknown |
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English |
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envir manag |
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envir manag Slimane, Manel Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
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description |
Rutin was enzymatically acylated with hexadecanedioic acid, in tert‐amyl alcohol, by an immobilized lipase from Candida antartica “Novozym 435”. The effect of different techniques of water removal, temperature, concentration of rutin and diacid/rutin molar ratio was investigated. The obtained results indicated that drying the media by adding the molecular sieves in the outer loop of the reactor was the most efficient method leading to water content lower than 200 ppm. The highest performances (conversion yield and initial rate) were reached at 90°C, 131 mM of rutin, and 118 mM of acid. Depending on the water content and the diacid/rutin molar ratio, only rutin 4‴‐hexadecanedioate or both rutin 4‴‐hexadecanedioate and dirutin 4‴, 4‴‐hexadecanedioate were synthesized. |
format |
Book |
author |
Slimane, Manel |
author_facet |
Slimane, Manel |
author_sort |
Slimane, Manel |
title |
Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
title_short |
Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
title_full |
Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
title_fullStr |
Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
title_full_unstemmed |
Biocatalysis of Rutin Hexadecanedioate Derivatives: Effect of Operating Conditions on Acylation Performance and Selectivity |
title_sort |
biocatalysis of rutin hexadecanedioate derivatives: effect of operating conditions on acylation performance and selectivity |
publisher |
IntechOpen |
publishDate |
2017 |
url |
https://doi.org/10.5772/67621 https://openresearchlibrary.org/ext/api/media/fbb5d244-8c7f-4b42-b666-6f9283f70be6/assets/external_content.pdf https://openresearchlibrary.org/viewer/fbb5d244-8c7f-4b42-b666-6f9283f70be6 |
genre |
antartic* |
genre_facet |
antartic* |
op_source |
Open Research Library |
op_relation |
ISBN:9789535134237 doi:10.5772/67621 10670/1.eer8rf https://openresearchlibrary.org/ext/api/media/fbb5d244-8c7f-4b42-b666-6f9283f70be6/assets/external_content.pdf https://openresearchlibrary.org/viewer/fbb5d244-8c7f-4b42-b666-6f9283f70be6 |
op_rights |
lic_creative-commons |
op_doi |
https://doi.org/10.5772/67621 |
_version_ |
1766288051792773120 |