Bivalve models of aging and the determination of molluscan lifespans
Abstract Bivalves are newly discovered models of natural aging. This invertebrate group includes species with the longest metazoan lifespan approaching 400 years, as well as species of swimming and sessile lifestyles that live just for 1 year. Bivalves from natural populations can be aged by shell g...
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fttrinitycoll:oai:tara.tcd.ie:2262/43199 2023-05-15T13:53:00+02:00 Bivalve models of aging and the determination of molluscan lifespans 2010-12-14T18:21:56Z http://hdl.handle.net/2262/43199 https://doi.org/10.1016/j.exger.2009.02.012 en eng Elsevier 05315565 (ISSN) S0531-5565(09)00035-7 (PII) S0531-5565(09)00035-7 (publisherID) http://hdl.handle.net/2262/43199 Experimental Gerontology 44 5 307 doi:10.1016/j.exger.2009.02.012 2009 12 months Bivalve longevity aging stress tolerance heterozygosity Antarctic genes metabolic rate depression 2010 fttrinitycoll https://doi.org/10.1016/j.exger.2009.02.012 2020-02-16T13:49:40Z Abstract Bivalves are newly discovered models of natural aging. This invertebrate group includes species with the longest metazoan lifespan approaching 400 years, as well as species of swimming and sessile lifestyles that live just for 1 year. Bivalves from natural populations can be aged by shell growth bands formed at regular intervals of time. This enables the study of abiotic and biotic environment factors (temperature, salinity, predator and physical disturbance) on senescence and fitness in natural populations, and distinguishes the impact of extrinsic effectors from intrinsic (genetic) determinantes of animal aging. Extreme longevity of some bivalve models may help to analyze general metabolic strategies thought to be life prolonging, like the transient depression of metabolism, which forms part of natural behaviour in these species. Thus, seasonal food shortage experienced by benthic filter feeding bivalves in polar and temperate seas may mimic caloric restriction in vertebrates. Incidence of malignant neoplasms in bivalves needs to be investigated, to determine the implication of late acting mutations for bivalve longevity. Finally, bivalves are applicable models for testing the implication of heterozygosity of multiple genes for physiological tolerance, adaptability (heterozygote superiority), and life expectancy. correspondance: Corresponding author. (Abele, Doris) Doris.abele@awi.de (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Brey, Thomas) Institute for Clinical Molecular Biology--> , Schittenhelmstrasse 12--> , 24105 Kiel--> - GERMANY (Philipp, Eva) GERMANY Received: 2008-10-17 Revised: 2009-02-21 Accepted: 2009-02-23 Other/Unknown Material Antarc* Antarctic The University of Dublin, Trinity College: TARA (Trinity's Access to Research Archive) Antarctic Experimental Gerontology 44 5 307 315 |
institution |
Open Polar |
collection |
The University of Dublin, Trinity College: TARA (Trinity's Access to Research Archive) |
op_collection_id |
fttrinitycoll |
language |
English |
topic |
Bivalve longevity aging stress tolerance heterozygosity Antarctic genes metabolic rate depression |
spellingShingle |
Bivalve longevity aging stress tolerance heterozygosity Antarctic genes metabolic rate depression Bivalve models of aging and the determination of molluscan lifespans |
topic_facet |
Bivalve longevity aging stress tolerance heterozygosity Antarctic genes metabolic rate depression |
description |
Abstract Bivalves are newly discovered models of natural aging. This invertebrate group includes species with the longest metazoan lifespan approaching 400 years, as well as species of swimming and sessile lifestyles that live just for 1 year. Bivalves from natural populations can be aged by shell growth bands formed at regular intervals of time. This enables the study of abiotic and biotic environment factors (temperature, salinity, predator and physical disturbance) on senescence and fitness in natural populations, and distinguishes the impact of extrinsic effectors from intrinsic (genetic) determinantes of animal aging. Extreme longevity of some bivalve models may help to analyze general metabolic strategies thought to be life prolonging, like the transient depression of metabolism, which forms part of natural behaviour in these species. Thus, seasonal food shortage experienced by benthic filter feeding bivalves in polar and temperate seas may mimic caloric restriction in vertebrates. Incidence of malignant neoplasms in bivalves needs to be investigated, to determine the implication of late acting mutations for bivalve longevity. Finally, bivalves are applicable models for testing the implication of heterozygosity of multiple genes for physiological tolerance, adaptability (heterozygote superiority), and life expectancy. correspondance: Corresponding author. (Abele, Doris) Doris.abele@awi.de (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Abele, Doris) Alfred-Wegener-Institut for Polar and Marine Research--> , Am Handelshafen 12--> , 27570 Bremerhaven--> - GERMANY (Brey, Thomas) Institute for Clinical Molecular Biology--> , Schittenhelmstrasse 12--> , 24105 Kiel--> - GERMANY (Philipp, Eva) GERMANY Received: 2008-10-17 Revised: 2009-02-21 Accepted: 2009-02-23 |
title |
Bivalve models of aging and the determination of molluscan lifespans |
title_short |
Bivalve models of aging and the determination of molluscan lifespans |
title_full |
Bivalve models of aging and the determination of molluscan lifespans |
title_fullStr |
Bivalve models of aging and the determination of molluscan lifespans |
title_full_unstemmed |
Bivalve models of aging and the determination of molluscan lifespans |
title_sort |
bivalve models of aging and the determination of molluscan lifespans |
publisher |
Elsevier |
publishDate |
2010 |
url |
http://hdl.handle.net/2262/43199 https://doi.org/10.1016/j.exger.2009.02.012 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
05315565 (ISSN) S0531-5565(09)00035-7 (PII) S0531-5565(09)00035-7 (publisherID) http://hdl.handle.net/2262/43199 Experimental Gerontology 44 5 307 doi:10.1016/j.exger.2009.02.012 |
op_rights |
2009 12 months |
op_doi |
https://doi.org/10.1016/j.exger.2009.02.012 |
container_title |
Experimental Gerontology |
container_volume |
44 |
container_issue |
5 |
container_start_page |
307 |
op_container_end_page |
315 |
_version_ |
1766257944578490368 |