Changes in Cytokines at Extreme Surroundings in Antarctica
We evaluated the impact of the extreme environmental conditions at high altitudes in Antarctica on health from the viewpoint of cytokines. The subjects were 7 men who joined an inland research party participating in the 40th Japanese Antarctic Research Expedition. They underwent serial hematological...
Main Authors: | , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Tottori University Faculty of Medicine
2003
|
Subjects: | |
Online Access: | https://repository.lib.tottori-u.ac.jp/?action=repository_uri&item_id=5102 http://id.nii.ac.jp/1824/00005096/ https://repository.lib.tottori-u.ac.jp/?action=repository_action_common_download&item_id=5102&item_no=1&attribute_id=22&file_no=1 |
id |
fttottoriuniv:oai:repository.lib.tottori-u.ac.jp:00005102 |
---|---|
record_format |
openpolar |
spelling |
fttottoriuniv:oai:repository.lib.tottori-u.ac.jp:00005102 2023-09-05T13:15:17+02:00 Changes in Cytokines at Extreme Surroundings in Antarctica Otani Shinji Kusagaya Hiromitsu 2003-06 https://repository.lib.tottori-u.ac.jp/?action=repository_uri&item_id=5102 http://id.nii.ac.jp/1824/00005096/ https://repository.lib.tottori-u.ac.jp/?action=repository_action_common_download&item_id=5102&item_no=1&attribute_id=22&file_no=1 en eng Tottori University Faculty of Medicine https://repository.lib.tottori-u.ac.jp/?action=repository_uri&item_id=5102 http://id.nii.ac.jp/1824/00005096/ Yonago Acta medica = Yonago Acta medica, 46(2), 29-34(2003-06) 13468049 AA00892882 https://repository.lib.tottori-u.ac.jp/?action=repository_action_common_download&item_id=5102&item_no=1&attribute_id=22&file_no=1 Yonago Acta medica 編集委員会 Yonago Acta medica. 2003, 46(2), 29-34 Antarctica cytokine high altitude interleukin-6 mountain sickness Journal Article 2003 fttottoriuniv 2023-08-13T14:03:31Z We evaluated the impact of the extreme environmental conditions at high altitudes in Antarctica on health from the viewpoint of cytokines. The subjects were 7 men who joined an inland research party participating in the 40th Japanese Antarctic Research Expedition. They underwent serial hematological examinations during the expedition for over 100 days at high altitudes (the highest point was 3810 m). The serum concentration of erythropoietin (EPO) increased promptly, indicating its usefulness for altitude adaptation. The serum concentration of interleukin-6 (IL-6) increased at high altitudes, and showed 2 peaks. Changes in IL-6 levels did not correlate with arterial oxygen tension, serum C-reactive protein or EPO levels. Some psychological stress and various factors may be related to IL-6 levels. Since the subject who suffered bone fractures had a very high concentration of IL-6 and his symptoms of mountain sickness were severer than the others, elevation of IL-6 may be related with mountain sickness. All subjects remained in relatively good health for 3 months. It is thought that the human body can protect itself against extreme surroundings in Antarctica. Article in Journal/Newspaper Antarc* Antarctic Antarctica Tottori University Research Result Repository Antarctic |
institution |
Open Polar |
collection |
Tottori University Research Result Repository |
op_collection_id |
fttottoriuniv |
language |
English |
topic |
Antarctica cytokine high altitude interleukin-6 mountain sickness |
spellingShingle |
Antarctica cytokine high altitude interleukin-6 mountain sickness Otani Shinji Kusagaya Hiromitsu Changes in Cytokines at Extreme Surroundings in Antarctica |
topic_facet |
Antarctica cytokine high altitude interleukin-6 mountain sickness |
description |
We evaluated the impact of the extreme environmental conditions at high altitudes in Antarctica on health from the viewpoint of cytokines. The subjects were 7 men who joined an inland research party participating in the 40th Japanese Antarctic Research Expedition. They underwent serial hematological examinations during the expedition for over 100 days at high altitudes (the highest point was 3810 m). The serum concentration of erythropoietin (EPO) increased promptly, indicating its usefulness for altitude adaptation. The serum concentration of interleukin-6 (IL-6) increased at high altitudes, and showed 2 peaks. Changes in IL-6 levels did not correlate with arterial oxygen tension, serum C-reactive protein or EPO levels. Some psychological stress and various factors may be related to IL-6 levels. Since the subject who suffered bone fractures had a very high concentration of IL-6 and his symptoms of mountain sickness were severer than the others, elevation of IL-6 may be related with mountain sickness. All subjects remained in relatively good health for 3 months. It is thought that the human body can protect itself against extreme surroundings in Antarctica. |
format |
Article in Journal/Newspaper |
author |
Otani Shinji Kusagaya Hiromitsu |
author_facet |
Otani Shinji Kusagaya Hiromitsu |
author_sort |
Otani Shinji |
title |
Changes in Cytokines at Extreme Surroundings in Antarctica |
title_short |
Changes in Cytokines at Extreme Surroundings in Antarctica |
title_full |
Changes in Cytokines at Extreme Surroundings in Antarctica |
title_fullStr |
Changes in Cytokines at Extreme Surroundings in Antarctica |
title_full_unstemmed |
Changes in Cytokines at Extreme Surroundings in Antarctica |
title_sort |
changes in cytokines at extreme surroundings in antarctica |
publisher |
Tottori University Faculty of Medicine |
publishDate |
2003 |
url |
https://repository.lib.tottori-u.ac.jp/?action=repository_uri&item_id=5102 http://id.nii.ac.jp/1824/00005096/ https://repository.lib.tottori-u.ac.jp/?action=repository_action_common_download&item_id=5102&item_no=1&attribute_id=22&file_no=1 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_source |
Yonago Acta medica. 2003, 46(2), 29-34 |
op_relation |
https://repository.lib.tottori-u.ac.jp/?action=repository_uri&item_id=5102 http://id.nii.ac.jp/1824/00005096/ Yonago Acta medica = Yonago Acta medica, 46(2), 29-34(2003-06) 13468049 AA00892882 https://repository.lib.tottori-u.ac.jp/?action=repository_action_common_download&item_id=5102&item_no=1&attribute_id=22&file_no=1 |
op_rights |
Yonago Acta medica 編集委員会 |
_version_ |
1776197087667421184 |