Comprehensive two-dimensional liquid chromatography and hyphenated liquid chromatography to study the degradation of poly(bisphenol A)carbonate:

• Main Authors: Coulier, L., Kaal, E.R., Hankemeier, T.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2005
• Subjects: Packaging; Analytical research; Degradation; GPEC; LC x SEC; LC-CC; MALDI-TOF-MS; Poly(bisphenol A)carbonate; Two-dimensional liquid chromatography; Alcohols; Biodegradation; Hydrolysis; Molecular weight; Polymers; Size exclusion chromatography; Gradient polymer elution chromatography (GPEC); Hydrolytic degradation; Molecular mass; Liquid chromatography; 4,4' isopropylidenediphenol; carbonic acid derivative; analytic method; article; chemical reaction kinetics; gel permeation chromatography; hydrolysis kinetics; matrix assisted laser desorption ionization time of flight mass spectrometry; priority journal; Chromatography; Gel; Spectrometry; Mass; Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Ultraviolet; Carbonic acid
• Online Access: http://resolver.tudelft.nl/uuid:3981e83e-7efb-461f-973f-62d5ffe9dba7

Size exclusion chromatography (SEC), gradient polymer elution chromatography (GPEC) and liquid chromatography at critical conditions (LC-CC) have been developed and applied to observe chemical changes in poly(bisphenol A)carbonate (PC) due to hydrolytic degradation. Especially LC-CC appeared to be very successful to observe differences in functionality of PC as result of hydrolytic degradation. Observed differences due to degradation could be identified by (semi) on-line coupling to matrix assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF-MS). The differences in functionality could be attributed to the formation of different end-groups, i.e. OH end-groups. In addition, comprehensive two-dimensional liquid chromatography (2D-LC) has been applied successfully to study the hydrolytic degradation of PC. LC-CC x SEC showed that the formation of PC with different end-groups occurred over the whole molecular mass range. This information could not be obtained with the separate liquid chromatographic techniques, thereby illustrating the added value of 2D-LC. © 2005 Elsevier B.V. All rights reserved.