Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men
Several epidemiological studies have pointed at serum uric acid (SUA) as an independent risk factor for mortality, diabetes, hypertension, cardiovascular and kidney disease; however, no clear pathogenic pathway is established. Uric acid (UA) crystals show pro-inflammatory properties and can thus cre...
Published in: | Scientific Reports |
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Main Authors: | , , , , , , |
Format: | Report |
Language: | English |
Published: |
Springer Nature
2019
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Subjects: | |
Online Access: | http://hdl.handle.net/11250/2634513 https://doi.org/10.1038/s41598-019-46935-w |