High prevalence of markers of coronary heart disease among Greenland Inuit
Udgivelsesdato: 2008-Feb OBJECTIVE: It is a common notion that coronary heart disease (CHD) is rare among the Inuit, possibly due to a high intake of omega-3-fatty acids. The scientific evidence for this is weak and to some extent based on uncertain mortality statistic. The aim of this study was to...
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ftsydanskunivpub:oai:sdu.dk:publications/b66b8810-474c-11dd-9fbe-000ea68e967b 2024-05-19T07:41:06+00:00 High prevalence of markers of coronary heart disease among Greenland Inuit Jørgensen, Marit Eika Bjerregaard, Peter Kjaergaard, Jens Jørgen Borch-Johnsen, Knut 2008-02-01 https://portal.findresearcher.sdu.dk/da/publications/b66b8810-474c-11dd-9fbe-000ea68e967b https://doi.org/10.1016/j.atherosclerosis.2007.01.008 eng eng https://portal.findresearcher.sdu.dk/da/publications/b66b8810-474c-11dd-9fbe-000ea68e967b info:eu-repo/semantics/restrictedAccess Jørgensen , M E , Bjerregaard , P , Kjaergaard , J J & Borch-Johnsen , K 2008 , ' High prevalence of markers of coronary heart disease among Greenland Inuit ' , Atherosclerosis , vol. 196 , no. 2 , pp. 772-778 . https://doi.org/10.1016/j.atherosclerosis.2007.01.008 Adolescent Adult Aged Angina Pectoris Biological Markers Coronary Disease Electrocardiography Female Greenland Humans Inuits Male Middle Aged Myocardial Infarction Prevalence article 2008 ftsydanskunivpub https://doi.org/10.1016/j.atherosclerosis.2007.01.008 2024-05-01T00:14:11Z Udgivelsesdato: 2008-Feb OBJECTIVE: It is a common notion that coronary heart disease (CHD) is rare among the Inuit, possibly due to a high intake of omega-3-fatty acids. The scientific evidence for this is weak and to some extent based on uncertain mortality statistic. The aim of this study was to assess the prevalence of markers of CHD among Greenland Inuit, and to study associations between markers of CHD and behavioral and biological variables. DESIGN: We studied prevalence of angina pectoris (AP), self-reported myocardial infarction (MI), and ECG defined MI and ischaemia in a population survey among 1316 Inuit living in Greenland. Blood tests were supplemented by structured interviews, anthropometry, and measurements of blood pressure, and the participants received an oral glucose tolerance test. RESULTS: The prevalence of symptomatic CHD (AP, self-reported MI) was 7.3% among men and 6.9% among women, and 12.2% and 13.4% of men and women had ischaemic ECG changes. The overall prevalence of CHD (AP+self-reported MI+ECG defined MI) was 10.8% in men and 10.2% in women. The highest prevalence was observed in the least westernized areas in Greenland. Physical inactivity, low education, dyslipidemia, hypertension and diabetes were associated with CHD. CONCLUSION: The prevalence of markers of CHD was not different from that in Western populations. The Inuit is a population undergoing rapid social and health transitions, with the emergence of cardiovascular risk factors, and there is a need for critical rethinking of cardiovascular epidemiology in this population. Article in Journal/Newspaper Greenland inuit inuits University of Southern Denmark Research Portal Atherosclerosis 196 2 772 778 |
institution |
Open Polar |
collection |
University of Southern Denmark Research Portal |
op_collection_id |
ftsydanskunivpub |
language |
English |
topic |
Adolescent Adult Aged Angina Pectoris Biological Markers Coronary Disease Electrocardiography Female Greenland Humans Inuits Male Middle Aged Myocardial Infarction Prevalence |
spellingShingle |
Adolescent Adult Aged Angina Pectoris Biological Markers Coronary Disease Electrocardiography Female Greenland Humans Inuits Male Middle Aged Myocardial Infarction Prevalence Jørgensen, Marit Eika Bjerregaard, Peter Kjaergaard, Jens Jørgen Borch-Johnsen, Knut High prevalence of markers of coronary heart disease among Greenland Inuit |
topic_facet |
Adolescent Adult Aged Angina Pectoris Biological Markers Coronary Disease Electrocardiography Female Greenland Humans Inuits Male Middle Aged Myocardial Infarction Prevalence |
description |
Udgivelsesdato: 2008-Feb OBJECTIVE: It is a common notion that coronary heart disease (CHD) is rare among the Inuit, possibly due to a high intake of omega-3-fatty acids. The scientific evidence for this is weak and to some extent based on uncertain mortality statistic. The aim of this study was to assess the prevalence of markers of CHD among Greenland Inuit, and to study associations between markers of CHD and behavioral and biological variables. DESIGN: We studied prevalence of angina pectoris (AP), self-reported myocardial infarction (MI), and ECG defined MI and ischaemia in a population survey among 1316 Inuit living in Greenland. Blood tests were supplemented by structured interviews, anthropometry, and measurements of blood pressure, and the participants received an oral glucose tolerance test. RESULTS: The prevalence of symptomatic CHD (AP, self-reported MI) was 7.3% among men and 6.9% among women, and 12.2% and 13.4% of men and women had ischaemic ECG changes. The overall prevalence of CHD (AP+self-reported MI+ECG defined MI) was 10.8% in men and 10.2% in women. The highest prevalence was observed in the least westernized areas in Greenland. Physical inactivity, low education, dyslipidemia, hypertension and diabetes were associated with CHD. CONCLUSION: The prevalence of markers of CHD was not different from that in Western populations. The Inuit is a population undergoing rapid social and health transitions, with the emergence of cardiovascular risk factors, and there is a need for critical rethinking of cardiovascular epidemiology in this population. |
format |
Article in Journal/Newspaper |
author |
Jørgensen, Marit Eika Bjerregaard, Peter Kjaergaard, Jens Jørgen Borch-Johnsen, Knut |
author_facet |
Jørgensen, Marit Eika Bjerregaard, Peter Kjaergaard, Jens Jørgen Borch-Johnsen, Knut |
author_sort |
Jørgensen, Marit Eika |
title |
High prevalence of markers of coronary heart disease among Greenland Inuit |
title_short |
High prevalence of markers of coronary heart disease among Greenland Inuit |
title_full |
High prevalence of markers of coronary heart disease among Greenland Inuit |
title_fullStr |
High prevalence of markers of coronary heart disease among Greenland Inuit |
title_full_unstemmed |
High prevalence of markers of coronary heart disease among Greenland Inuit |
title_sort |
high prevalence of markers of coronary heart disease among greenland inuit |
publishDate |
2008 |
url |
https://portal.findresearcher.sdu.dk/da/publications/b66b8810-474c-11dd-9fbe-000ea68e967b https://doi.org/10.1016/j.atherosclerosis.2007.01.008 |
genre |
Greenland inuit inuits |
genre_facet |
Greenland inuit inuits |
op_source |
Jørgensen , M E , Bjerregaard , P , Kjaergaard , J J & Borch-Johnsen , K 2008 , ' High prevalence of markers of coronary heart disease among Greenland Inuit ' , Atherosclerosis , vol. 196 , no. 2 , pp. 772-778 . https://doi.org/10.1016/j.atherosclerosis.2007.01.008 |
op_relation |
https://portal.findresearcher.sdu.dk/da/publications/b66b8810-474c-11dd-9fbe-000ea68e967b |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/j.atherosclerosis.2007.01.008 |
container_title |
Atherosclerosis |
container_volume |
196 |
container_issue |
2 |
container_start_page |
772 |
op_container_end_page |
778 |
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