Environmental chemical exposures among Greenlandic children in relation to diet and residence
The objective of this study was to identify geographic, dietary, and other predictors for childhood exposure to perfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and methylmercury in Greenlandic children. The study includes cross-sectional data from 367 Greenlandic children aged 7...
Published in: | International Journal of Circumpolar Health |
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2019
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Online Access: | https://portal.findresearcher.sdu.dk/da/publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 https://doi.org/10.1080/22423982.2019.1642090 https://findresearcher.sdu.dk/ws/files/152574879/Environmental_chemical_exposures_among_Greenlandic_children_in_relation_to_diet_and_residence.pdf |
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ftsydanskunivpub:oai:sdu.dk:publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 2024-09-15T18:02:08+00:00 Environmental chemical exposures among Greenlandic children in relation to diet and residence Timmermann, Clara Amalie Gade Pedersen, Henning Sloth Budtz-Jørgensen, Esben Bjerregaard, Peter Oulhote, Youssef Weihe, Pál Nielsen, Flemming Grandjean, Philippe 2019-12 application/pdf https://portal.findresearcher.sdu.dk/da/publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 https://doi.org/10.1080/22423982.2019.1642090 https://findresearcher.sdu.dk/ws/files/152574879/Environmental_chemical_exposures_among_Greenlandic_children_in_relation_to_diet_and_residence.pdf eng eng https://portal.findresearcher.sdu.dk/da/publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 info:eu-repo/semantics/openAccess Timmermann , C A G , Pedersen , H S , Budtz-Jørgensen , E , Bjerregaard , P , Oulhote , Y , Weihe , P , Nielsen , F & Grandjean , P 2019 , ' Environmental chemical exposures among Greenlandic children in relation to diet and residence ' , International Journal of Circumpolar Health , vol. 78 , no. 1 , 1642090 . https://doi.org/10.1080/22423982.2019.1642090 article 2019 ftsydanskunivpub https://doi.org/10.1080/22423982.2019.1642090 2024-07-08T23:47:00Z The objective of this study was to identify geographic, dietary, and other predictors for childhood exposure to perfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and methylmercury in Greenlandic children. The study includes cross-sectional data from 367 Greenlandic children aged 7 to 12 years examined during 2012-2015. A parent or guardian participated in a structured interview, and a blood sample from the child was analysed for PFASs, PCBs and total mercury. Predictors for the environmental exposures were identified using linear regression. Area of residence was found to have the strongest explanatory power, accounting for 24% to 68% of the variance in the serum concentrations. Information about diet was available for two-thirds of the children, and among these, consumption of traditional Greenlandic food accounted for 2% to 10% of the variance in the biomarker concentrations. Models including all predictors associated with at least one of the environmental chemicals explained 19% to 54% of the total variance. In conclusion, area is a likely proxy for a traditional marine diet, and together area and diet constitute the most important predictors of exposure to methylmercury, PCBs and PFASs among Greenlandic children. Article in Journal/Newspaper Circumpolar Health greenlandic International Journal of Circumpolar Health University of Southern Denmark Research Portal International Journal of Circumpolar Health 78 1 1642090 |
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University of Southern Denmark Research Portal |
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ftsydanskunivpub |
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English |
description |
The objective of this study was to identify geographic, dietary, and other predictors for childhood exposure to perfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and methylmercury in Greenlandic children. The study includes cross-sectional data from 367 Greenlandic children aged 7 to 12 years examined during 2012-2015. A parent or guardian participated in a structured interview, and a blood sample from the child was analysed for PFASs, PCBs and total mercury. Predictors for the environmental exposures were identified using linear regression. Area of residence was found to have the strongest explanatory power, accounting for 24% to 68% of the variance in the serum concentrations. Information about diet was available for two-thirds of the children, and among these, consumption of traditional Greenlandic food accounted for 2% to 10% of the variance in the biomarker concentrations. Models including all predictors associated with at least one of the environmental chemicals explained 19% to 54% of the total variance. In conclusion, area is a likely proxy for a traditional marine diet, and together area and diet constitute the most important predictors of exposure to methylmercury, PCBs and PFASs among Greenlandic children. |
format |
Article in Journal/Newspaper |
author |
Timmermann, Clara Amalie Gade Pedersen, Henning Sloth Budtz-Jørgensen, Esben Bjerregaard, Peter Oulhote, Youssef Weihe, Pál Nielsen, Flemming Grandjean, Philippe |
spellingShingle |
Timmermann, Clara Amalie Gade Pedersen, Henning Sloth Budtz-Jørgensen, Esben Bjerregaard, Peter Oulhote, Youssef Weihe, Pál Nielsen, Flemming Grandjean, Philippe Environmental chemical exposures among Greenlandic children in relation to diet and residence |
author_facet |
Timmermann, Clara Amalie Gade Pedersen, Henning Sloth Budtz-Jørgensen, Esben Bjerregaard, Peter Oulhote, Youssef Weihe, Pál Nielsen, Flemming Grandjean, Philippe |
author_sort |
Timmermann, Clara Amalie Gade |
title |
Environmental chemical exposures among Greenlandic children in relation to diet and residence |
title_short |
Environmental chemical exposures among Greenlandic children in relation to diet and residence |
title_full |
Environmental chemical exposures among Greenlandic children in relation to diet and residence |
title_fullStr |
Environmental chemical exposures among Greenlandic children in relation to diet and residence |
title_full_unstemmed |
Environmental chemical exposures among Greenlandic children in relation to diet and residence |
title_sort |
environmental chemical exposures among greenlandic children in relation to diet and residence |
publishDate |
2019 |
url |
https://portal.findresearcher.sdu.dk/da/publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 https://doi.org/10.1080/22423982.2019.1642090 https://findresearcher.sdu.dk/ws/files/152574879/Environmental_chemical_exposures_among_Greenlandic_children_in_relation_to_diet_and_residence.pdf |
genre |
Circumpolar Health greenlandic International Journal of Circumpolar Health |
genre_facet |
Circumpolar Health greenlandic International Journal of Circumpolar Health |
op_source |
Timmermann , C A G , Pedersen , H S , Budtz-Jørgensen , E , Bjerregaard , P , Oulhote , Y , Weihe , P , Nielsen , F & Grandjean , P 2019 , ' Environmental chemical exposures among Greenlandic children in relation to diet and residence ' , International Journal of Circumpolar Health , vol. 78 , no. 1 , 1642090 . https://doi.org/10.1080/22423982.2019.1642090 |
op_relation |
https://portal.findresearcher.sdu.dk/da/publications/96763c99-b0b6-4576-b2ec-dc2c74de9177 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1080/22423982.2019.1642090 |
container_title |
International Journal of Circumpolar Health |
container_volume |
78 |
container_issue |
1 |
container_start_page |
1642090 |
_version_ |
1810439396665589760 |