Decrease in vitamin d status in the greenlandic adult population from 1987-2010
BACKGROUND: Low vitamin D status may be pronounced in Arctic populations due to limited sun exposure and decreasing intake of traditional food. OBJECTIVE: To investigate serum 25(OH)D3 as a measure of vitamin D status among adult Inuit in Greenland, predictors of low serum 25(OH)D3 concentrations an...
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2014
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Online Access: | https://portal.findresearcher.sdu.dk/da/publications/30b06baf-19da-424a-a6a3-8c932a7293a6 https://doi.org/10.1371/journal.pone.0112949 |
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ftsydanskunivpub:oai:sdu.dk:publications/30b06baf-19da-424a-a6a3-8c932a7293a6 2024-09-15T18:09:40+00:00 Decrease in vitamin d status in the greenlandic adult population from 1987-2010 Nielsen, Nina O Jørgensen, Marit E Friis, Henrik Melbye, Mads Soborg, Bolette Jeppesen, Charlotte Lundqvist, Marika Cohen, Arieh Hougaard, David M Bjerregaard, Peter 2014-12-02 https://portal.findresearcher.sdu.dk/da/publications/30b06baf-19da-424a-a6a3-8c932a7293a6 https://doi.org/10.1371/journal.pone.0112949 eng eng https://portal.findresearcher.sdu.dk/da/publications/30b06baf-19da-424a-a6a3-8c932a7293a6 info:eu-repo/semantics/restrictedAccess Nielsen , N O , Jørgensen , M E , Friis , H , Melbye , M , Soborg , B , Jeppesen , C , Lundqvist , M , Cohen , A , Hougaard , D M & Bjerregaard , P 2014 , ' Decrease in vitamin d status in the greenlandic adult population from 1987-2010 ' , PLOS ONE , vol. 9 , no. 12 , e112949 . https://doi.org/10.1371/journal.pone.0112949 article 2014 ftsydanskunivpub https://doi.org/10.1371/journal.pone.0112949 2024-07-01T23:45:10Z BACKGROUND: Low vitamin D status may be pronounced in Arctic populations due to limited sun exposure and decreasing intake of traditional food. OBJECTIVE: To investigate serum 25(OH)D3 as a measure of vitamin D status among adult Inuit in Greenland, predictors of low serum 25(OH)D3 concentrations and the trend from 1987 to 2005-2010. DESIGN: A total of 2877 randomly selected Inuit (≥18 years) from the Inuit Health in Transition study were included. A sub-sample (n = 330) donated a blood sample in 1987 which allowed assessment of time trends in vitamin D status. RESULTS: The geometric mean serum 25(OH)D3 (25[OH]D2 concentrations were negligible and not reported) in 2005-2010 was lowest among the 18-29 year old individuals (30.7 nmol/L; 95% CI: 29.7; 31.7) and increased with age. In all age-groups it decreased from 1987 to 2005-2010 (32%-58%). Low 25(OH)D3 concentrations (<50 nmol/L) were present in 77% of the 18-29 year old and decreased with age. A characteristic seasonal variation in 25(OH)D3 concentrations was observed (range 33.2-57.1 nmol/L, p<0.001), with the highest concentrations in August to October. Age (2.0% per year increase; CI: 1.7, 2.2), female gender (7.1%; CI: 2.0; 12.5), alcohol intake (0.2% per increase in drinks/week; 0.0; 0.4), and traditional diet (10.0% per 100 g/d increase; CI: 7.9; 12.1) were associated with increased serum 25(OH)D3, whereas smoking (-11.6%; CI: -16.2; -6.9), BMI (-0.6%; CI: -1.1; -0.2) and latitude (-0.7% per degree increase; CI: -1.3; -0.2) were associated with decreased concentrations. CONCLUSION: We identified a remarkable decrease in vitamin D status from 1987 to 2005-2010 and a presently low vitamin D status among Inuit in Greenland. A change away from a traditional diet may well explain the observed decline. The study argues for the need of increased dietary intake of vitamin D and supplementation might be considered. Article in Journal/Newspaper Greenland greenlandic inuit University of Southern Denmark Research Portal PLoS ONE 9 12 e112949 |
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Open Polar |
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University of Southern Denmark Research Portal |
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ftsydanskunivpub |
language |
English |
description |
BACKGROUND: Low vitamin D status may be pronounced in Arctic populations due to limited sun exposure and decreasing intake of traditional food. OBJECTIVE: To investigate serum 25(OH)D3 as a measure of vitamin D status among adult Inuit in Greenland, predictors of low serum 25(OH)D3 concentrations and the trend from 1987 to 2005-2010. DESIGN: A total of 2877 randomly selected Inuit (≥18 years) from the Inuit Health in Transition study were included. A sub-sample (n = 330) donated a blood sample in 1987 which allowed assessment of time trends in vitamin D status. RESULTS: The geometric mean serum 25(OH)D3 (25[OH]D2 concentrations were negligible and not reported) in 2005-2010 was lowest among the 18-29 year old individuals (30.7 nmol/L; 95% CI: 29.7; 31.7) and increased with age. In all age-groups it decreased from 1987 to 2005-2010 (32%-58%). Low 25(OH)D3 concentrations (<50 nmol/L) were present in 77% of the 18-29 year old and decreased with age. A characteristic seasonal variation in 25(OH)D3 concentrations was observed (range 33.2-57.1 nmol/L, p<0.001), with the highest concentrations in August to October. Age (2.0% per year increase; CI: 1.7, 2.2), female gender (7.1%; CI: 2.0; 12.5), alcohol intake (0.2% per increase in drinks/week; 0.0; 0.4), and traditional diet (10.0% per 100 g/d increase; CI: 7.9; 12.1) were associated with increased serum 25(OH)D3, whereas smoking (-11.6%; CI: -16.2; -6.9), BMI (-0.6%; CI: -1.1; -0.2) and latitude (-0.7% per degree increase; CI: -1.3; -0.2) were associated with decreased concentrations. CONCLUSION: We identified a remarkable decrease in vitamin D status from 1987 to 2005-2010 and a presently low vitamin D status among Inuit in Greenland. A change away from a traditional diet may well explain the observed decline. The study argues for the need of increased dietary intake of vitamin D and supplementation might be considered. |
format |
Article in Journal/Newspaper |
author |
Nielsen, Nina O Jørgensen, Marit E Friis, Henrik Melbye, Mads Soborg, Bolette Jeppesen, Charlotte Lundqvist, Marika Cohen, Arieh Hougaard, David M Bjerregaard, Peter |
spellingShingle |
Nielsen, Nina O Jørgensen, Marit E Friis, Henrik Melbye, Mads Soborg, Bolette Jeppesen, Charlotte Lundqvist, Marika Cohen, Arieh Hougaard, David M Bjerregaard, Peter Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
author_facet |
Nielsen, Nina O Jørgensen, Marit E Friis, Henrik Melbye, Mads Soborg, Bolette Jeppesen, Charlotte Lundqvist, Marika Cohen, Arieh Hougaard, David M Bjerregaard, Peter |
author_sort |
Nielsen, Nina O |
title |
Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
title_short |
Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
title_full |
Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
title_fullStr |
Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
title_full_unstemmed |
Decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
title_sort |
decrease in vitamin d status in the greenlandic adult population from 1987-2010 |
publishDate |
2014 |
url |
https://portal.findresearcher.sdu.dk/da/publications/30b06baf-19da-424a-a6a3-8c932a7293a6 https://doi.org/10.1371/journal.pone.0112949 |
genre |
Greenland greenlandic inuit |
genre_facet |
Greenland greenlandic inuit |
op_source |
Nielsen , N O , Jørgensen , M E , Friis , H , Melbye , M , Soborg , B , Jeppesen , C , Lundqvist , M , Cohen , A , Hougaard , D M & Bjerregaard , P 2014 , ' Decrease in vitamin d status in the greenlandic adult population from 1987-2010 ' , PLOS ONE , vol. 9 , no. 12 , e112949 . https://doi.org/10.1371/journal.pone.0112949 |
op_relation |
https://portal.findresearcher.sdu.dk/da/publications/30b06baf-19da-424a-a6a3-8c932a7293a6 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1371/journal.pone.0112949 |
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PLoS ONE |
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9 |
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12 |
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e112949 |
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1810447240308719616 |