Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent
In situ immobilization of enzyme into metal–organic frameworks (MOFs) is performed through a one-step and facile method. Candida antarctica lipase B (CalB) is directly embedded in zeolitic imidazolate framework (ZIF)-8 by simply mixing an aqueous solution of 2-methylimidazole and zinc nitrate hexahy...
Published in: | Frontiers in Bioengineering and Biotechnology |
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2020
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Online Access: | https://portal.findresearcher.sdu.dk/da/publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da https://doi.org/10.3389/fbioe.2020.00714 https://findresearcher.sdu.dk/ws/files/171914249/fbioe_08_00714.pdf |
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ftsydanskunivpub:oai:sdu.dk:publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da 2024-04-28T08:01:49+00:00 Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent Wang, Yangxin Zhang, Ningning Tan, Deming Qi, Zhenhui Wu, Changzhu 2020-07-07 application/pdf https://portal.findresearcher.sdu.dk/da/publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da https://doi.org/10.3389/fbioe.2020.00714 https://findresearcher.sdu.dk/ws/files/171914249/fbioe_08_00714.pdf eng eng https://portal.findresearcher.sdu.dk/da/publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da info:eu-repo/semantics/openAccess Wang , Y , Zhang , N , Tan , D , Qi , Z & Wu , C 2020 , ' Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent ' , Frontiers in Bioengineering and Biotechnology , vol. 8 , 714 . https://doi.org/10.3389/fbioe.2020.00714 biocatalysis enzymatic reactions heterogeneous catalysis metal–organic frameworks size-selective catalysis article 2020 ftsydanskunivpub https://doi.org/10.3389/fbioe.2020.00714 2024-04-03T15:30:27Z In situ immobilization of enzyme into metal–organic frameworks (MOFs) is performed through a one-step and facile method. Candida antarctica lipase B (CalB) is directly embedded in zeolitic imidazolate framework (ZIF)-8 by simply mixing an aqueous solution of 2-methylimidazole and zinc nitrate hexahydrate [Zn(NO 3 ) 2 ⋅6H 2 O] containing CalB at room temperature. Due to the intrinsic micropores of ZIF-8, the obtained CalB@ZIF composite is successfully applied in size-selective transesterification reaction in organic solvent. CalB@ZIF not only shows much higher catalytic activity but also exhibits higher thermal stability than free CalB. Besides, the robust ZIF-8 shell also offers the hybrid composites excellent reusability. Article in Journal/Newspaper Antarc* Antarctica University of Southern Denmark Research Portal Frontiers in Bioengineering and Biotechnology 8 |
institution |
Open Polar |
collection |
University of Southern Denmark Research Portal |
op_collection_id |
ftsydanskunivpub |
language |
English |
topic |
biocatalysis enzymatic reactions heterogeneous catalysis metal–organic frameworks size-selective catalysis |
spellingShingle |
biocatalysis enzymatic reactions heterogeneous catalysis metal–organic frameworks size-selective catalysis Wang, Yangxin Zhang, Ningning Tan, Deming Qi, Zhenhui Wu, Changzhu Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
topic_facet |
biocatalysis enzymatic reactions heterogeneous catalysis metal–organic frameworks size-selective catalysis |
description |
In situ immobilization of enzyme into metal–organic frameworks (MOFs) is performed through a one-step and facile method. Candida antarctica lipase B (CalB) is directly embedded in zeolitic imidazolate framework (ZIF)-8 by simply mixing an aqueous solution of 2-methylimidazole and zinc nitrate hexahydrate [Zn(NO 3 ) 2 ⋅6H 2 O] containing CalB at room temperature. Due to the intrinsic micropores of ZIF-8, the obtained CalB@ZIF composite is successfully applied in size-selective transesterification reaction in organic solvent. CalB@ZIF not only shows much higher catalytic activity but also exhibits higher thermal stability than free CalB. Besides, the robust ZIF-8 shell also offers the hybrid composites excellent reusability. |
format |
Article in Journal/Newspaper |
author |
Wang, Yangxin Zhang, Ningning Tan, Deming Qi, Zhenhui Wu, Changzhu |
author_facet |
Wang, Yangxin Zhang, Ningning Tan, Deming Qi, Zhenhui Wu, Changzhu |
author_sort |
Wang, Yangxin |
title |
Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
title_short |
Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
title_full |
Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
title_fullStr |
Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
title_full_unstemmed |
Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent |
title_sort |
facile synthesis of enzyme-embedded metal–organic frameworks for size-selective biocatalysis in organic solvent |
publishDate |
2020 |
url |
https://portal.findresearcher.sdu.dk/da/publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da https://doi.org/10.3389/fbioe.2020.00714 https://findresearcher.sdu.dk/ws/files/171914249/fbioe_08_00714.pdf |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Wang , Y , Zhang , N , Tan , D , Qi , Z & Wu , C 2020 , ' Facile Synthesis of Enzyme-Embedded Metal–Organic Frameworks for Size-Selective Biocatalysis in Organic Solvent ' , Frontiers in Bioengineering and Biotechnology , vol. 8 , 714 . https://doi.org/10.3389/fbioe.2020.00714 |
op_relation |
https://portal.findresearcher.sdu.dk/da/publications/2ab34d63-3391-47e5-9a7f-2eba1c5ef3da |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.3389/fbioe.2020.00714 |
container_title |
Frontiers in Bioengineering and Biotechnology |
container_volume |
8 |
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1797573399431610368 |