MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes
In recent years working memory deficits have been reported in users of MDMA (3,4-methylenedioxymethamphetamine, ecstasy). The current study aimed to assess the impact of MDMA use on three separate central executive processes (set shifting, inhibition and memory updating) and also on 'prefrontal...
Published in: | Journal of Psychopharmacology |
---|---|
Main Authors: | , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
Sage
2006
|
Subjects: | |
Online Access: | http://hdl.handle.net/1959.3/45616 https://doi.org/10.1177/0269881106063269 |
id |
ftswinburne:tle:9e070cbd-f4da-486e-8342-8a2456e54e11:28f49f06-0da8-44be-9edc-ad1dd0a9c582:1 |
---|---|
record_format |
openpolar |
spelling |
ftswinburne:tle:9e070cbd-f4da-486e-8342-8a2456e54e11:28f49f06-0da8-44be-9edc-ad1dd0a9c582:1 2023-05-15T18:33:51+02:00 MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes Reay, Jonathon L. Hamilton, Colin J. Kennedy, David O. Scholey, A. B. Swinburne University of Technology 2006 http://hdl.handle.net/1959.3/45616 https://doi.org/10.1177/0269881106063269 unknown Sage http://hdl.handle.net/1959.3/45616 https://doi.org/10.1177/0269881106063269 Copyright © 2006 British Association for Psychopharmacology. Journal of Psychopharmacology, Vol. 20, no. 3 (May 2006), pp. 385-388 Journal article 2006 ftswinburne https://doi.org/10.1177/0269881106063269 2019-09-07T20:45:35Z In recent years working memory deficits have been reported in users of MDMA (3,4-methylenedioxymethamphetamine, ecstasy). The current study aimed to assess the impact of MDMA use on three separate central executive processes (set shifting, inhibition and memory updating) and also on 'prefrontal' mediated social and emotional judgement processes. Fifteen polydrug ecstasy users and 15 polydrug non-ecstasy user controls completed a general drug use questionnaire, the Brixton Spatial Anticipation task (set shifting), Backward Digit Span procedure (memory updating), Inhibition of Return (inhibition), an emotional intelligence scale, the Tromso Social Intelligence Scale and the Dysexecutive Questionnaire (DEX). Compared with MDMA-free polydrug controls, MDMA polydrug users showed impairments in set shifting and memory updating, and also in social and emotional judgement processes. The latter two deficits remained significant after controlling for other drug use. These data lend further support to the proposal that cognitive processes mediated by the prefrontal cortex may be impaired by recreational ecstasy use. Article in Journal/Newspaper Tromso Tromso Swinburne University of Technology: Swinburne Research Bank Tromso ENVELOPE(16.546,16.546,68.801,68.801) Journal of Psychopharmacology 20 3 385 388 |
institution |
Open Polar |
collection |
Swinburne University of Technology: Swinburne Research Bank |
op_collection_id |
ftswinburne |
language |
unknown |
description |
In recent years working memory deficits have been reported in users of MDMA (3,4-methylenedioxymethamphetamine, ecstasy). The current study aimed to assess the impact of MDMA use on three separate central executive processes (set shifting, inhibition and memory updating) and also on 'prefrontal' mediated social and emotional judgement processes. Fifteen polydrug ecstasy users and 15 polydrug non-ecstasy user controls completed a general drug use questionnaire, the Brixton Spatial Anticipation task (set shifting), Backward Digit Span procedure (memory updating), Inhibition of Return (inhibition), an emotional intelligence scale, the Tromso Social Intelligence Scale and the Dysexecutive Questionnaire (DEX). Compared with MDMA-free polydrug controls, MDMA polydrug users showed impairments in set shifting and memory updating, and also in social and emotional judgement processes. The latter two deficits remained significant after controlling for other drug use. These data lend further support to the proposal that cognitive processes mediated by the prefrontal cortex may be impaired by recreational ecstasy use. |
author2 |
Swinburne University of Technology |
format |
Article in Journal/Newspaper |
author |
Reay, Jonathon L. Hamilton, Colin J. Kennedy, David O. Scholey, A. B. |
spellingShingle |
Reay, Jonathon L. Hamilton, Colin J. Kennedy, David O. Scholey, A. B. MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
author_facet |
Reay, Jonathon L. Hamilton, Colin J. Kennedy, David O. Scholey, A. B. |
author_sort |
Reay, Jonathon L. |
title |
MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
title_short |
MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
title_full |
MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
title_fullStr |
MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
title_full_unstemmed |
MDMA polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
title_sort |
mdma polydrug users show process-specific central executive impairments coupled with impaired social and emotional judgement processes |
publisher |
Sage |
publishDate |
2006 |
url |
http://hdl.handle.net/1959.3/45616 https://doi.org/10.1177/0269881106063269 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
geographic |
Tromso |
geographic_facet |
Tromso |
genre |
Tromso Tromso |
genre_facet |
Tromso Tromso |
op_source |
Journal of Psychopharmacology, Vol. 20, no. 3 (May 2006), pp. 385-388 |
op_relation |
http://hdl.handle.net/1959.3/45616 https://doi.org/10.1177/0269881106063269 |
op_rights |
Copyright © 2006 British Association for Psychopharmacology. |
op_doi |
https://doi.org/10.1177/0269881106063269 |
container_title |
Journal of Psychopharmacology |
container_volume |
20 |
container_issue |
3 |
container_start_page |
385 |
op_container_end_page |
388 |
_version_ |
1766218483684605952 |