Undetected cancer in clinical prostate biopsies

• Main Authors: Eduard Chelebian, Carolina Wählby, Anders Bergh
• Other Authors: Christophe Avenel, Pernilla Andersson, Helena Järemo
• Format: Other/Unknown Material
• Language: English
• Published: Uppsala universitet 2024
• Subjects: VETENSKAP OCH TEKNOLOGI; SCIENCE AND TECHNOLOGY; https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=ScienceAndTechnology; Informationsteknik; Information technology; https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=ScienceAndTechnology.InformationTechnology; Datorseende och robotik (autonoma system); Computer Vision and Robotics (Autonomous Systems); Medicinsk bildbehandling; Medical Image Processing; Medicin och hälsovetenskap; Medical and Health Sciences; Cancer och onkologi; Cancer and Oncology; Urologi och njurmedicin; Urology and Nephrology; Data- och informationsvetenskap (Datateknik); Computer and Information Science; Medicinteknik; Medical Engineering; Klinisk medicin; Clinical Medicine; Teknik; Engineering and Technology; Naturvetenskap; Natural Sciences; Northern Sweden
• Online Access: https://doi.org/10.57804/ed55-4479

Datasetet består av digitiserade godartade prostata H&E-biopsier från män med förhöjda PSA-värden. För mer information, se beskrivning på engelska: This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up. The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis. Conversely, 88 case patients with 254 biopsies were diagnosed with PCa of various ISUP grades within the 30 months following the initial diagnosis. Each case patient is accompanied by one to three control patients, paired for similar age, PSA value and year of diagnosis. Patients were anonymized by assigning random case IDs and MRXS image files were anonymized by using the module in https://github.com/bgilbert/anonymize-slide. This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, ...