Nitro derivatives from the Arctic ice bacterium Salegenfibacter sp isolate T436

• Published in: The Journal of Antibiotics
• Main Authors: Schuhmann, Imelda, Yao, Clarisse B. Fotso-Fondja, Al-Zereini, Wael, Anke, Heidrun, Helmke, Elisabeth, Laatsch, Hartmut
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Japan Antibiotics Research Assoc 2009
• Subjects: Arctic
• Online Access: https://resolver.sub.uni-goettingen.de/purl?gro-2/16178; https://doi.org/10.1038/ja.2009.71

Twenty-five aromatic nitro, dinitro and trinitro compounds were isolated in low yields of less than 1 mgl(-1) from a Salegentibacter sp. strain T436 derived from Arctic pack ice. Their structures were elucidated by MS and NMR techniques. Seven of these compounds, namely, 2-hydroxy-3-(4'-hydroxy-3'-nitrophenyl)-propionic acid methyl ester (6), 2-chloro-3-(4'-hydroxy-3'-nitrophenyl)propionic acid methyl ester (7), 3-(4'-hydroxy-3',5'-dinitrophenyl)-propionic acid methyl ester (14), 4'-hydroxy-3',5'-dinitrophenylethylchloride (16), (4'-hydroxy-3',5'-dinitrophenyl)-2-chloropropionic acid methyl ester (17), N-acetyl-3',5'-dinitrotyramine (18) and 2,6-dinitro-4-(2'-nitroethenyl)phenol (19) are new, and five are reported in this study from a natural source for the first time. The Journal of Antibiotics (2009) 62, 453-460; doi:10.1038/ja.2009.71; published online 31 July 2009 Ministry of Education and Research [03FO348A]