Phocine distemper Virus : current knowledge and future directions
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp an...
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ftstandrewserep:oai:research-repository.st-andrews.ac.uk:10023/5995 2023-07-02T03:31:24+02:00 Phocine distemper Virus : current knowledge and future directions Duignan, P.J. Van Bressem, M.-F. Baker, J.D. Barbieri, M. Colegrove, K.M. de Guise, S. de Swart, R.L. di Guardo, G. Dobson, A. Duprex, W.P. Early, G. Fauquier, D. Goldstein, T. Goodman, S.J. Grenfell, B. Groch, K.R. Gulland, F. Hall, A. Jensen, B.A. Lamy, K. Matassa, K. Mazzariol, S. Morris, S.E. Nielsen, O. Rotstein, D. Rowles, T.K. Saliki, J.T. Siebert, U. Waltzek, T. Wellehan, J.F. NERC University of St Andrews. School of Biology University of St Andrews. Sea Mammal Research Unit University of St Andrews. Marine Alliance for Science & Technology Scotland University of St Andrews. Scottish Oceans Institute 2015-01-14T15:31:02Z 42 application/pdf http://hdl.handle.net/10023/5995 https://doi.org/10.3390/v6125093 eng eng Viruses Duignan , P J , Van Bressem , M-F , Baker , J D , Barbieri , M , Colegrove , K M , de Guise , S , de Swart , R L , di Guardo , G , Dobson , A , Duprex , W P , Early , G , Fauquier , D , Goldstein , T , Goodman , S J , Grenfell , B , Groch , K R , Gulland , F , Hall , A , Jensen , B A , Lamy , K , Matassa , K , Mazzariol , S , Morris , S E , Nielsen , O , Rotstein , D , Rowles , T K , Saliki , J T , Siebert , U , Waltzek , T & Wellehan , J F 2014 , ' Phocine distemper Virus : current knowledge and future directions ' , Viruses , vol. 6 , no. 12 , pp. 5093-5134 . https://doi.org/10.3390/v6125093 1999-4915 PURE: 161866991 PURE UUID: 09cb3e02-8bc9-48ce-aed5-65dc9e9f0bdc Scopus: 84919819797 WOS: 000346834500015 ORCID: /0000-0002-7562-1771/work/47136266 http://hdl.handle.net/10023/5995 https://doi.org/10.3390/v6125093 Agreement R8-H12-86 © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). Morbillivirus Pinnipeds Sea otter CD150/SLAM Phylogeny Pathology Epidemiology Immunity Vaccine QH301 Biology QR355 Virology SDG 3 - Good Health and Well-being QH301 QR355 Journal article 2015 ftstandrewserep https://doi.org/10.3390/v6125093 2023-06-13T18:27:45Z Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years. Publisher PDF Peer reviewed Article in Journal/Newspaper Arctic Elephant Seal harbor seal North Atlantic University of St Andrews: Digital Research Repository Arctic Pacific Viruses 6 12 5093 5134 |
institution |
Open Polar |
collection |
University of St Andrews: Digital Research Repository |
op_collection_id |
ftstandrewserep |
language |
English |
topic |
Morbillivirus Pinnipeds Sea otter CD150/SLAM Phylogeny Pathology Epidemiology Immunity Vaccine QH301 Biology QR355 Virology SDG 3 - Good Health and Well-being QH301 QR355 |
spellingShingle |
Morbillivirus Pinnipeds Sea otter CD150/SLAM Phylogeny Pathology Epidemiology Immunity Vaccine QH301 Biology QR355 Virology SDG 3 - Good Health and Well-being QH301 QR355 Duignan, P.J. Van Bressem, M.-F. Baker, J.D. Barbieri, M. Colegrove, K.M. de Guise, S. de Swart, R.L. di Guardo, G. Dobson, A. Duprex, W.P. Early, G. Fauquier, D. Goldstein, T. Goodman, S.J. Grenfell, B. Groch, K.R. Gulland, F. Hall, A. Jensen, B.A. Lamy, K. Matassa, K. Mazzariol, S. Morris, S.E. Nielsen, O. Rotstein, D. Rowles, T.K. Saliki, J.T. Siebert, U. Waltzek, T. Wellehan, J.F. Phocine distemper Virus : current knowledge and future directions |
topic_facet |
Morbillivirus Pinnipeds Sea otter CD150/SLAM Phylogeny Pathology Epidemiology Immunity Vaccine QH301 Biology QR355 Virology SDG 3 - Good Health and Well-being QH301 QR355 |
description |
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years. Publisher PDF Peer reviewed |
author2 |
NERC University of St Andrews. School of Biology University of St Andrews. Sea Mammal Research Unit University of St Andrews. Marine Alliance for Science & Technology Scotland University of St Andrews. Scottish Oceans Institute |
format |
Article in Journal/Newspaper |
author |
Duignan, P.J. Van Bressem, M.-F. Baker, J.D. Barbieri, M. Colegrove, K.M. de Guise, S. de Swart, R.L. di Guardo, G. Dobson, A. Duprex, W.P. Early, G. Fauquier, D. Goldstein, T. Goodman, S.J. Grenfell, B. Groch, K.R. Gulland, F. Hall, A. Jensen, B.A. Lamy, K. Matassa, K. Mazzariol, S. Morris, S.E. Nielsen, O. Rotstein, D. Rowles, T.K. Saliki, J.T. Siebert, U. Waltzek, T. Wellehan, J.F. |
author_facet |
Duignan, P.J. Van Bressem, M.-F. Baker, J.D. Barbieri, M. Colegrove, K.M. de Guise, S. de Swart, R.L. di Guardo, G. Dobson, A. Duprex, W.P. Early, G. Fauquier, D. Goldstein, T. Goodman, S.J. Grenfell, B. Groch, K.R. Gulland, F. Hall, A. Jensen, B.A. Lamy, K. Matassa, K. Mazzariol, S. Morris, S.E. Nielsen, O. Rotstein, D. Rowles, T.K. Saliki, J.T. Siebert, U. Waltzek, T. Wellehan, J.F. |
author_sort |
Duignan, P.J. |
title |
Phocine distemper Virus : current knowledge and future directions |
title_short |
Phocine distemper Virus : current knowledge and future directions |
title_full |
Phocine distemper Virus : current knowledge and future directions |
title_fullStr |
Phocine distemper Virus : current knowledge and future directions |
title_full_unstemmed |
Phocine distemper Virus : current knowledge and future directions |
title_sort |
phocine distemper virus : current knowledge and future directions |
publishDate |
2015 |
url |
http://hdl.handle.net/10023/5995 https://doi.org/10.3390/v6125093 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic Elephant Seal harbor seal North Atlantic |
genre_facet |
Arctic Elephant Seal harbor seal North Atlantic |
op_relation |
Viruses Duignan , P J , Van Bressem , M-F , Baker , J D , Barbieri , M , Colegrove , K M , de Guise , S , de Swart , R L , di Guardo , G , Dobson , A , Duprex , W P , Early , G , Fauquier , D , Goldstein , T , Goodman , S J , Grenfell , B , Groch , K R , Gulland , F , Hall , A , Jensen , B A , Lamy , K , Matassa , K , Mazzariol , S , Morris , S E , Nielsen , O , Rotstein , D , Rowles , T K , Saliki , J T , Siebert , U , Waltzek , T & Wellehan , J F 2014 , ' Phocine distemper Virus : current knowledge and future directions ' , Viruses , vol. 6 , no. 12 , pp. 5093-5134 . https://doi.org/10.3390/v6125093 1999-4915 PURE: 161866991 PURE UUID: 09cb3e02-8bc9-48ce-aed5-65dc9e9f0bdc Scopus: 84919819797 WOS: 000346834500015 ORCID: /0000-0002-7562-1771/work/47136266 http://hdl.handle.net/10023/5995 https://doi.org/10.3390/v6125093 Agreement R8-H12-86 |
op_rights |
© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
op_doi |
https://doi.org/10.3390/v6125093 |
container_title |
Viruses |
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6 |
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12 |
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5093 |
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1770270807903174656 |