First evidence of anticancer and antimicrobial activity in Mediterranean mesopelagic species.

• Published in: Scientific Reports
• Main Authors: Lauritano, Chiara, Martínez, Kevin A, Battaglia, Pietro, Granata, Antonia, de la Cruz, Mercedes, Cautain, Bastien, Martín, Jesús, Reyes, Fernando, Ianora, Adrianna, Guglielmo, Letterio
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2020
• Subjects: Anti-Infective Agents; Antineoplastic Agents; Aquatic Organisms; Biological Products; Chemical Fractionation; Chromatography; High Pressure Liquid; Liquid; Humans; Mass Spectrometry; Mediterranean Sea; Methicillin-Resistant Staphylococcus aureus; Mycobacterium tuberculosis; Eta; Meganyctiphanes norvegica
• Online Access: http://hdl.handle.net/10668/15263; https://doi.org/10.1038/s41598-020-61515-z; https://www.nature.com/articles/s41598-020-61515-z.pdf; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080843/pdf

Mesopelagic organisms form huge biomass aggregations, supporting important pelagic trophic webs and several top predators. Although some studies on the occurrence, biology and ecology of these organisms are available, to date there are no investigations on their potential use for anticancer and anti...