Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system
Immobilized Candida antarctica lipase B catalyzed the synthesis of triglycerides from glycerol and phenylalkanoic acids in a solvent-free system. 4-Phenylbutyric acid was the best acyl donor and displayed the highest synthetic rate of triphenylbutyrin (glyceryl triphenylbutyrate) at 65 °C among vari...
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ftsoutherntaiwan:oai:ir.lib.stust.edu.tw:987654321/5340 2023-05-15T13:35:24+02:00 Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system 張春生 Chun-Sheng Chang; Pei-Lin Wu 生物科技系所 2007 http://ir.lib.stust.edu.tw/handle/987654321/5340 en_US eng Elsevier Journal of Biotechnology, Volume 127, Issue 4, 20 January 2007, Pages 694-702 http://ir.lib.stust.edu.tw/handle/987654321/5340 Glyceride synthesis Lipase Phenylalkanoic acids Phenylbutyric acid Solvent-free Triphenylbutyrin 12 2007 ftsoutherntaiwan 2018-11-09T01:09:48Z Immobilized Candida antarctica lipase B catalyzed the synthesis of triglycerides from glycerol and phenylalkanoic acids in a solvent-free system. 4-Phenylbutyric acid was the best acyl donor and displayed the highest synthetic rate of triphenylbutyrin (glyceryl triphenylbutyrate) at 65 °C among various phenylalkanoic acids with straight alkyl chains. The external mass transfer between the immobilized lipase and the bulk reaction mixture was limited. Different methods of removing water during the lipase-catalyzed esterification including spontaneous evaporation, the use of saturated salts solutions, and the use of molecular sieves were studied. The highest yield of triphenylbutyrin at 65 °C was 98%, by the elimination of water using molecular sieves in a solvent-free system. The glycerol was almost completely esterified to triphenylbutyrin in excess phenylbutyric acid with various substrate molar ratios. Other/Unknown Material Antarc* Antarctica Southern Taiwan University Institutional Repository (STUTIR) |
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Southern Taiwan University Institutional Repository (STUTIR) |
op_collection_id |
ftsoutherntaiwan |
language |
English |
topic |
Glyceride synthesis Lipase Phenylalkanoic acids Phenylbutyric acid Solvent-free Triphenylbutyrin 12 |
spellingShingle |
Glyceride synthesis Lipase Phenylalkanoic acids Phenylbutyric acid Solvent-free Triphenylbutyrin 12 張春生 Chun-Sheng Chang; Pei-Lin Wu Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
topic_facet |
Glyceride synthesis Lipase Phenylalkanoic acids Phenylbutyric acid Solvent-free Triphenylbutyrin 12 |
description |
Immobilized Candida antarctica lipase B catalyzed the synthesis of triglycerides from glycerol and phenylalkanoic acids in a solvent-free system. 4-Phenylbutyric acid was the best acyl donor and displayed the highest synthetic rate of triphenylbutyrin (glyceryl triphenylbutyrate) at 65 °C among various phenylalkanoic acids with straight alkyl chains. The external mass transfer between the immobilized lipase and the bulk reaction mixture was limited. Different methods of removing water during the lipase-catalyzed esterification including spontaneous evaporation, the use of saturated salts solutions, and the use of molecular sieves were studied. The highest yield of triphenylbutyrin at 65 °C was 98%, by the elimination of water using molecular sieves in a solvent-free system. The glycerol was almost completely esterified to triphenylbutyrin in excess phenylbutyric acid with various substrate molar ratios. |
author2 |
生物科技系所 |
author |
張春生 Chun-Sheng Chang; Pei-Lin Wu |
author_facet |
張春生 Chun-Sheng Chang; Pei-Lin Wu |
author_sort |
張春生 |
title |
Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
title_short |
Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
title_full |
Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
title_fullStr |
Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
title_full_unstemmed |
Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
title_sort |
synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system |
publisher |
Elsevier |
publishDate |
2007 |
url |
http://ir.lib.stust.edu.tw/handle/987654321/5340 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
Journal of Biotechnology, Volume 127, Issue 4, 20 January 2007, Pages 694-702 http://ir.lib.stust.edu.tw/handle/987654321/5340 |
_version_ |
1766065172717240320 |