Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country
This work was initially designed to identify risk factors that may be associated with the HIV epidemic in Djibouti. The value of this research led to the establishment of an epidemiological surveillance system for HIV. But we cannot develop an alone surveillance system without addressing the epidemi...
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Language: | French |
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ftsorbonneuniv:oai:HAL:tel-00813143v1 2023-06-11T04:10:24+02:00 Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country Influence des comportements à risque sur l'épidémiologie du VIH à Djibouti et mise en place d'un système d'alerte précoce aux épidémies dans un contexte de ressources limitées Ahmed, Ammar Abdo Epidémiologie des maladies infectieuses et modélisation (ESIM) Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM) Department of Epidemiology and Health Information Ministry of Health- Djibouti Université Pierre et Marie Curie - Paris VI Antoine Flahault Department of Health Ministry of Health Djibouti 2009-07-17 https://theses.hal.science/tel-00813143 https://theses.hal.science/tel-00813143/document https://theses.hal.science/tel-00813143/file/These_V0.pdf fr fre HAL CCSD NNT: 2009PA066315 tel-00813143 https://theses.hal.science/tel-00813143 https://theses.hal.science/tel-00813143/document https://theses.hal.science/tel-00813143/file/These_V0.pdf info:eu-repo/semantics/OpenAccess https://theses.hal.science/tel-00813143 Santé publique et épidémiologie. Université Pierre et Marie Curie - Paris VI, 2009. Français. ⟨NNT : 2009PA066315⟩ Epidemiology of HIV Blood transfusion Risk behavior Early Warning System Entomological surveillance Khat-chewing Épidémiologie du VIH Transfusion sanguine Comportements à risque Système d'alerte précoce surveillance entomologique Choléra Khat Hygiène [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie info:eu-repo/semantics/doctoralThesis Theses 2009 ftsorbonneuniv 2023-05-29T16:14:40Z This work was initially designed to identify risk factors that may be associated with the HIV epidemic in Djibouti. The value of this research led to the establishment of an epidemiological surveillance system for HIV. But we cannot develop an alone surveillance system without addressing the epidemiological surveillance system in its entirety. Which system suffered from a lack of resources, low adherence of the healthcare system and lack of political will to make it a tool for decision support. In this context, we conducted our research and we received all the political and technical support to meet this challenge in a developing country. With support from WHO, we have implemented a sentinel surveillance system for HIV that does not rely only risk group or limited area but on the general population through annual anonymous surveys noncorrelated. Actually, we move to the second generation surveillance. We have also established an integrated surveillance system for vaccinepreventable diseases (diphtheria, pertussis, neonatal tetanus, Poliomyelitis, Measles, Meningitis, Mumps and Rubella) and epidemic-prone diseases such as Cholera, Malaria, avian flu and hemorrhagic fevers. The surveillance approach is primarily a clinical or syndromic secondarily confirmed by biology. Two objectives have been attended: 1. Risk factors for HIV in Djibouti: This study found specific risk factors to our context; Khat consumption by the unemployed and blood transfusion are specifically associated with HIV infection in Djibouti. 2. Dynamics of the epidemic of cholera in the Horn of Africa (HoA), this study is nourished by a rich field experience that led to the monitoring of stowaways migrants of the cholera epidemic in the HoA. We discovered the emergence of a new serotype unknown in previous waves of cholera outbreaks. 11 In addition, we are not limited ourself in the establishment of a disease surveillance system on human level. We had been interested on vectors level. At Djibouti, vector-borne diseases constitute a public health ... Doctoral or Postdoctoral Thesis Avian flu HAL Sorbonne Université |
institution |
Open Polar |
collection |
HAL Sorbonne Université |
op_collection_id |
ftsorbonneuniv |
language |
French |
topic |
Epidemiology of HIV Blood transfusion Risk behavior Early Warning System Entomological surveillance Khat-chewing Épidémiologie du VIH Transfusion sanguine Comportements à risque Système d'alerte précoce surveillance entomologique Choléra Khat Hygiène [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
spellingShingle |
Epidemiology of HIV Blood transfusion Risk behavior Early Warning System Entomological surveillance Khat-chewing Épidémiologie du VIH Transfusion sanguine Comportements à risque Système d'alerte précoce surveillance entomologique Choléra Khat Hygiène [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Ahmed, Ammar Abdo Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
topic_facet |
Epidemiology of HIV Blood transfusion Risk behavior Early Warning System Entomological surveillance Khat-chewing Épidémiologie du VIH Transfusion sanguine Comportements à risque Système d'alerte précoce surveillance entomologique Choléra Khat Hygiène [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
description |
This work was initially designed to identify risk factors that may be associated with the HIV epidemic in Djibouti. The value of this research led to the establishment of an epidemiological surveillance system for HIV. But we cannot develop an alone surveillance system without addressing the epidemiological surveillance system in its entirety. Which system suffered from a lack of resources, low adherence of the healthcare system and lack of political will to make it a tool for decision support. In this context, we conducted our research and we received all the political and technical support to meet this challenge in a developing country. With support from WHO, we have implemented a sentinel surveillance system for HIV that does not rely only risk group or limited area but on the general population through annual anonymous surveys noncorrelated. Actually, we move to the second generation surveillance. We have also established an integrated surveillance system for vaccinepreventable diseases (diphtheria, pertussis, neonatal tetanus, Poliomyelitis, Measles, Meningitis, Mumps and Rubella) and epidemic-prone diseases such as Cholera, Malaria, avian flu and hemorrhagic fevers. The surveillance approach is primarily a clinical or syndromic secondarily confirmed by biology. Two objectives have been attended: 1. Risk factors for HIV in Djibouti: This study found specific risk factors to our context; Khat consumption by the unemployed and blood transfusion are specifically associated with HIV infection in Djibouti. 2. Dynamics of the epidemic of cholera in the Horn of Africa (HoA), this study is nourished by a rich field experience that led to the monitoring of stowaways migrants of the cholera epidemic in the HoA. We discovered the emergence of a new serotype unknown in previous waves of cholera outbreaks. 11 In addition, we are not limited ourself in the establishment of a disease surveillance system on human level. We had been interested on vectors level. At Djibouti, vector-borne diseases constitute a public health ... |
author2 |
Epidémiologie des maladies infectieuses et modélisation (ESIM) Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM) Department of Epidemiology and Health Information Ministry of Health- Djibouti Université Pierre et Marie Curie - Paris VI Antoine Flahault Department of Health Ministry of Health Djibouti |
format |
Doctoral or Postdoctoral Thesis |
author |
Ahmed, Ammar Abdo |
author_facet |
Ahmed, Ammar Abdo |
author_sort |
Ahmed, Ammar Abdo |
title |
Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
title_short |
Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
title_full |
Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
title_fullStr |
Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
title_full_unstemmed |
Risk factor of HIV in the Horn of Africa : a case control study in Djibouti and setting up an early warning system against outbreaks in limited ressources country |
title_sort |
risk factor of hiv in the horn of africa : a case control study in djibouti and setting up an early warning system against outbreaks in limited ressources country |
publisher |
HAL CCSD |
publishDate |
2009 |
url |
https://theses.hal.science/tel-00813143 https://theses.hal.science/tel-00813143/document https://theses.hal.science/tel-00813143/file/These_V0.pdf |
genre |
Avian flu |
genre_facet |
Avian flu |
op_source |
https://theses.hal.science/tel-00813143 Santé publique et épidémiologie. Université Pierre et Marie Curie - Paris VI, 2009. Français. ⟨NNT : 2009PA066315⟩ |
op_relation |
NNT: 2009PA066315 tel-00813143 https://theses.hal.science/tel-00813143 https://theses.hal.science/tel-00813143/document https://theses.hal.science/tel-00813143/file/These_V0.pdf |
op_rights |
info:eu-repo/semantics/OpenAccess |
_version_ |
1768384775253393408 |