Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG
Spike (S) glycoprotein is an important virulent factor for coronaviruses (CoVs), and variants of CoVs have been characterized based on S gene analysis. We present phylogenetic relationship of an isolated infectious bronchitis virus (IBV) strain with reference to the available genome and protein sequ...
Main Authors: | , , , , , , , , |
---|---|
Format: | Still Image |
Language: | unknown |
Published: |
2021
|
Subjects: | |
Online Access: | https://doi.org/10.3389/fvets.2021.794228.s001 |
id |
ftsmithonian:oai:figshare.com:article/17210528 |
---|---|
record_format |
openpolar |
spelling |
ftsmithonian:oai:figshare.com:article/17210528 2023-05-15T15:41:57+02:00 Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG Ghulam Abbas (764241) Yue Zhang (30585) Xiaowei Sun (318880) Huijie Chen (235980) Yudong Ren (302564) Xiurong Wang (561272) Muhammad Zulfiqar Ahmad (9026207) Xiaodan Huang (1521430) Guangxing Li (338141) 2021-12-16T04:32:20Z https://doi.org/10.3389/fvets.2021.794228.s001 unknown https://figshare.com/articles/figure/Image_1_Molecular_Characterization_of_Infectious_Bronchitis_Virus_Strain_HH06_Isolated_in_a_Poultry_Farm_in_Northeastern_China_JPEG/17210528 doi:10.3389/fvets.2021.794228.s001 CC BY 4.0 CC-BY Animal Systematics and Taxonomy Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Animal Behaviour Animal Cell and Molecular Biology Animal Developmental and Reproductive Biology Animal Immunology Animal Neurobiology Animal Physiological Ecology Animal Structure and Function Veterinary Anaesthesiology and Intensive Care Veterinary Anatomy and Physiology Veterinary Diagnosis and Diagnostics Veterinary Epidemiology Veterinary Immunology Veterinary Medicine Veterinary Microbiology (excl. Virology) Veterinary Parasitology Veterinary Pathology Veterinary Pharmacology Veterinary Surgery Veterinary Virology Veterinary Sciences not elsewhere classified molecular epidemiology zoonosis coronaviruses infectious bronchitis virus evolution Image Figure 2021 ftsmithonian https://doi.org/10.3389/fvets.2021.794228.s001 2021-12-19T19:23:16Z Spike (S) glycoprotein is an important virulent factor for coronaviruses (CoVs), and variants of CoVs have been characterized based on S gene analysis. We present phylogenetic relationship of an isolated infectious bronchitis virus (IBV) strain with reference to the available genome and protein sequences based on network, multiple sequence, selection pressure, and evolutionary fingerprinting analysis in People's Republic of China. One hundred and elven strains of CoVs i.e., Alphacoronaviruses (Alpha-CoVs; n = 12), Betacoronaviruses (Beta-CoVs; n = 37), Gammacoronaviruses (Gamma-CoVs; n = 46), and Deltacoronaviruses (Delta-CoVs; n = 16) were selected for this purpose. Phylogenetically, SARS-CoV-2 and SARS-CoVs clustered together with Bat-CoVs and MERS-CoV of Beta-CoVs (C). The IBV HH06 of Avian-CoVs was closely related to Duck-CoV and partridge S14, LDT3 (teal and chicken host). Beluga whale-CoV (SW1) and Bottlenose dolphin-CoVs of mammalian origin branched distantly from other animal origin viruses, however, making group with Avian-CoVs altogether into Gamma-CoVs. The motif analysis indicated well-conserved domains on S protein, which were similar within the same phylogenetic class and but variable at different domains of different origins. Recombination network tree indicated SARS-CoV-2, SARS-CoV, and Bat-CoVs, although branched differently, shared common clades. The MERS-CoVs of camel and human origin spread branched into a different clade, however, was closely associated closely with SARS-CoV-2, SARS-CoV, and Bat-CoVs. Whereas, HCoV-OC43 has human origin and branched together with bovine CoVs with but significant distant from other CoVs like SARS CoV-2 and SARS-CoV of human origin. These findings explain that CoVs' constant genetic recombination and evolutionary process that might maintain them as a potential veterinary and human epidemic threat. Still Image Beluga Beluga whale Beluga* Unknown Elven ENVELOPE(13.942,13.942,66.979,66.979) |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftsmithonian |
language |
unknown |
topic |
Animal Systematics and Taxonomy Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Animal Behaviour Animal Cell and Molecular Biology Animal Developmental and Reproductive Biology Animal Immunology Animal Neurobiology Animal Physiological Ecology Animal Structure and Function Veterinary Anaesthesiology and Intensive Care Veterinary Anatomy and Physiology Veterinary Diagnosis and Diagnostics Veterinary Epidemiology Veterinary Immunology Veterinary Medicine Veterinary Microbiology (excl. Virology) Veterinary Parasitology Veterinary Pathology Veterinary Pharmacology Veterinary Surgery Veterinary Virology Veterinary Sciences not elsewhere classified molecular epidemiology zoonosis coronaviruses infectious bronchitis virus evolution |
spellingShingle |
Animal Systematics and Taxonomy Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Animal Behaviour Animal Cell and Molecular Biology Animal Developmental and Reproductive Biology Animal Immunology Animal Neurobiology Animal Physiological Ecology Animal Structure and Function Veterinary Anaesthesiology and Intensive Care Veterinary Anatomy and Physiology Veterinary Diagnosis and Diagnostics Veterinary Epidemiology Veterinary Immunology Veterinary Medicine Veterinary Microbiology (excl. Virology) Veterinary Parasitology Veterinary Pathology Veterinary Pharmacology Veterinary Surgery Veterinary Virology Veterinary Sciences not elsewhere classified molecular epidemiology zoonosis coronaviruses infectious bronchitis virus evolution Ghulam Abbas (764241) Yue Zhang (30585) Xiaowei Sun (318880) Huijie Chen (235980) Yudong Ren (302564) Xiurong Wang (561272) Muhammad Zulfiqar Ahmad (9026207) Xiaodan Huang (1521430) Guangxing Li (338141) Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
topic_facet |
Animal Systematics and Taxonomy Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Animal Behaviour Animal Cell and Molecular Biology Animal Developmental and Reproductive Biology Animal Immunology Animal Neurobiology Animal Physiological Ecology Animal Structure and Function Veterinary Anaesthesiology and Intensive Care Veterinary Anatomy and Physiology Veterinary Diagnosis and Diagnostics Veterinary Epidemiology Veterinary Immunology Veterinary Medicine Veterinary Microbiology (excl. Virology) Veterinary Parasitology Veterinary Pathology Veterinary Pharmacology Veterinary Surgery Veterinary Virology Veterinary Sciences not elsewhere classified molecular epidemiology zoonosis coronaviruses infectious bronchitis virus evolution |
description |
Spike (S) glycoprotein is an important virulent factor for coronaviruses (CoVs), and variants of CoVs have been characterized based on S gene analysis. We present phylogenetic relationship of an isolated infectious bronchitis virus (IBV) strain with reference to the available genome and protein sequences based on network, multiple sequence, selection pressure, and evolutionary fingerprinting analysis in People's Republic of China. One hundred and elven strains of CoVs i.e., Alphacoronaviruses (Alpha-CoVs; n = 12), Betacoronaviruses (Beta-CoVs; n = 37), Gammacoronaviruses (Gamma-CoVs; n = 46), and Deltacoronaviruses (Delta-CoVs; n = 16) were selected for this purpose. Phylogenetically, SARS-CoV-2 and SARS-CoVs clustered together with Bat-CoVs and MERS-CoV of Beta-CoVs (C). The IBV HH06 of Avian-CoVs was closely related to Duck-CoV and partridge S14, LDT3 (teal and chicken host). Beluga whale-CoV (SW1) and Bottlenose dolphin-CoVs of mammalian origin branched distantly from other animal origin viruses, however, making group with Avian-CoVs altogether into Gamma-CoVs. The motif analysis indicated well-conserved domains on S protein, which were similar within the same phylogenetic class and but variable at different domains of different origins. Recombination network tree indicated SARS-CoV-2, SARS-CoV, and Bat-CoVs, although branched differently, shared common clades. The MERS-CoVs of camel and human origin spread branched into a different clade, however, was closely associated closely with SARS-CoV-2, SARS-CoV, and Bat-CoVs. Whereas, HCoV-OC43 has human origin and branched together with bovine CoVs with but significant distant from other CoVs like SARS CoV-2 and SARS-CoV of human origin. These findings explain that CoVs' constant genetic recombination and evolutionary process that might maintain them as a potential veterinary and human epidemic threat. |
format |
Still Image |
author |
Ghulam Abbas (764241) Yue Zhang (30585) Xiaowei Sun (318880) Huijie Chen (235980) Yudong Ren (302564) Xiurong Wang (561272) Muhammad Zulfiqar Ahmad (9026207) Xiaodan Huang (1521430) Guangxing Li (338141) |
author_facet |
Ghulam Abbas (764241) Yue Zhang (30585) Xiaowei Sun (318880) Huijie Chen (235980) Yudong Ren (302564) Xiurong Wang (561272) Muhammad Zulfiqar Ahmad (9026207) Xiaodan Huang (1521430) Guangxing Li (338141) |
author_sort |
Ghulam Abbas (764241) |
title |
Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
title_short |
Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
title_full |
Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
title_fullStr |
Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
title_full_unstemmed |
Image_1_Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern China.JPEG |
title_sort |
image_1_molecular characterization of infectious bronchitis virus strain hh06 isolated in a poultry farm in northeastern china.jpeg |
publishDate |
2021 |
url |
https://doi.org/10.3389/fvets.2021.794228.s001 |
long_lat |
ENVELOPE(13.942,13.942,66.979,66.979) |
geographic |
Elven |
geographic_facet |
Elven |
genre |
Beluga Beluga whale Beluga* |
genre_facet |
Beluga Beluga whale Beluga* |
op_relation |
https://figshare.com/articles/figure/Image_1_Molecular_Characterization_of_Infectious_Bronchitis_Virus_Strain_HH06_Isolated_in_a_Poultry_Farm_in_Northeastern_China_JPEG/17210528 doi:10.3389/fvets.2021.794228.s001 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fvets.2021.794228.s001 |
_version_ |
1766374827556339712 |